FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W39168122> ?p ?o ?g. }

• W39168122 abstract "In the past differentiation of human neutrophils has been defined by morphology, cytochemistry, or surface markers. In our experiments we have sequenced the various events that occur during the functional differentiation of the normal human neutrophil and have also examined some of the functional properties in relationship to surface markers and biochemical events. Granulocytes were obtained from the bone marrow and blood of hematologically normal individuals. Cells were separated into different stages of maturation by their physical properties using counterflow centrifugal elutriation and density gradient separation. Three cell fractions were obtained that were enriched for either immature myeloid cells, band neutrophils, or segmented neutrophils. Since the enriched fractions were not entirely pure, methodologies for functional assays were chosen that allowed cytologic evaluation of the functional capacity of each cell type. The criteria used to classify the stages of differentiation included both morphology by light microscopy and DNA labeling with tritiated thymidine. Various neutrophilic properties were studied: Fc receptors, complement receptors (CR1, CR3), phagocytosis of both live and dead opsonized Staphylococcus aureus, microbial killing of S aureus, NBT dye reduction after cellular stimulation with endotoxin, and chemotaxis. Our results indicate that the functional properties of the neutrophil appear in a distinct order. The sequence for the functional differentiation of the human neutrophil appears to be the following: Fc receptors----immune phagocytosis----complement receptors----oxygen-independent microbial killing----oxygen-dependent microbial killing----chemotaxis." @default.
• W39168122 created "2016-06-24" @default.
• W39168122 creator A5056085906 @default.
• W39168122 creator A5057100256 @default.
• W39168122 date "1987-03-01" @default.
• W39168122 modified "2023-09-26" @default.
• W39168122 title "Functional differentiation of normal human neutrophils" @default.
• W39168122 cites W106743832 @default.
• W39168122 cites W1493755175 @default.
• W39168122 cites W1497379843 @default.
• W39168122 cites W1526204886 @default.
• W39168122 cites W1609249008 @default.
• W39168122 cites W1637081772 @default.
• W39168122 cites W1819732475 @default.
• W39168122 cites W2001814527 @default.
• W39168122 cites W2012982812 @default.
• W39168122 cites W2062208099 @default.
• W39168122 cites W2062464235 @default.
• W39168122 cites W2073757021 @default.
• W39168122 cites W2084456057 @default.
• W39168122 cites W2087934471 @default.
• W39168122 cites W2118205899 @default.
• W39168122 cites W2119062616 @default.
• W39168122 cites W2139122389 @default.
• W39168122 cites W2163794178 @default.
• W39168122 cites W2169942948 @default.
• W39168122 cites W2253146081 @default.
• W39168122 cites W2312853837 @default.
• W39168122 cites W2317465896 @default.
• W39168122 cites W2319491530 @default.
• W39168122 cites W2323441341 @default.
• W39168122 cites W2416135392 @default.
• W39168122 cites W2416449692 @default.
• W39168122 cites W2442049207 @default.
• W39168122 cites W25441393 @default.
• W39168122 cites W69826027 @default.
• W39168122 cites W87350884 @default.
• W39168122 doi "https://doi.org/10.1182/blood.v69.3.937.bloodjournal693937" @default.
• W39168122 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3814822" @default.
• W39168122 hasPublicationYear "1987" @default.
• W39168122 type Work @default.
• W39168122 sameAs 39168122 @default.
• W39168122 citedByCount "55" @default.
• W39168122 countsByYear W391681222012 @default.
• W39168122 countsByYear W391681222013 @default.
• W39168122 countsByYear W391681222015 @default.
• W39168122 countsByYear W391681222017 @default.
• W39168122 countsByYear W391681222018 @default.
• W39168122 countsByYear W391681222019 @default.
• W39168122 countsByYear W391681222021 @default.
• W39168122 countsByYear W391681222022 @default.
• W39168122 crossrefType "journal-article" @default.
• W39168122 hasAuthorship W39168122A5056085906 @default.
• W39168122 hasAuthorship W39168122A5057100256 @default.
• W39168122 hasBestOaLocation W391681221 @default.
• W39168122 hasConcept C104317684 @default.
• W39168122 hasConcept C109159458 @default.
• W39168122 hasConcept C111684460 @default.
• W39168122 hasConcept C148738053 @default.
• W39168122 hasConcept C160448771 @default.
• W39168122 hasConcept C170493617 @default.
• W39168122 hasConcept C175773311 @default.
• W39168122 hasConcept C203014093 @default.
• W39168122 hasConcept C2779282312 @default.
• W39168122 hasConcept C28328180 @default.
• W39168122 hasConcept C54166955 @default.
• W39168122 hasConcept C55493867 @default.
• W39168122 hasConcept C86803240 @default.
• W39168122 hasConcept C8891405 @default.
• W39168122 hasConcept C89372155 @default.
• W39168122 hasConcept C95444343 @default.
• W39168122 hasConceptScore W39168122C104317684 @default.
• W39168122 hasConceptScore W39168122C109159458 @default.
• W39168122 hasConceptScore W39168122C111684460 @default.
• W39168122 hasConceptScore W39168122C148738053 @default.
• W39168122 hasConceptScore W39168122C160448771 @default.
• W39168122 hasConceptScore W39168122C170493617 @default.
• W39168122 hasConceptScore W39168122C175773311 @default.
• W39168122 hasConceptScore W39168122C203014093 @default.
• W39168122 hasConceptScore W39168122C2779282312 @default.
• W39168122 hasConceptScore W39168122C28328180 @default.
• W39168122 hasConceptScore W39168122C54166955 @default.
• W39168122 hasConceptScore W39168122C55493867 @default.
• W39168122 hasConceptScore W39168122C86803240 @default.
• W39168122 hasConceptScore W39168122C8891405 @default.
• W39168122 hasConceptScore W39168122C89372155 @default.
• W39168122 hasConceptScore W39168122C95444343 @default.
• W39168122 hasLocation W391681221 @default.
• W39168122 hasOpenAccess W39168122 @default.
• W39168122 hasPrimaryLocation W391681221 @default.
• W39168122 hasRelatedWork W146301169 @default.
• W39168122 hasRelatedWork W1497379843 @default.
• W39168122 hasRelatedWork W15642971 @default.
• W39168122 hasRelatedWork W15859992 @default.
• W39168122 hasRelatedWork W1934775191 @default.
• W39168122 hasRelatedWork W1966889578 @default.
• W39168122 hasRelatedWork W1974650703 @default.
• W39168122 hasRelatedWork W2000696348 @default.
• W39168122 hasRelatedWork W2001600351 @default.
• W39168122 hasRelatedWork W2001814527 @default.

• next