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• W39634557 abstract "Event Abstract Back to Event Demonstration of MMN in human subjects after stimulation with two complex deviant sounds Georgia Psiouri1*, Maria L. Stavrinou1, Andrew Koupparis1, Vassileios Kokkinos1 and George K. Kostopoulos1 1 University of Patras, Department of Physiology, Medical School, Greece Mismatch negativity (MMN) is a negative EEG potential evoked when a deviant stimulus interferes in a sequence of standard stimuli. It can be observed in many modalities: visual, olfactory, as well as auditory. We used auditory stimulation to evoke the MMN, in the form of a modified oddball paradigm, where at least 3 standard sound stimuli always preceded a deviant. Our deviant stimuli were of two kinds: one (D1) comprised of two simultaneous frequencies [800+700] Hz (of 100ms duration), and a second one (D2) of two consecutive frequencies [800 and 700] Hz lasting 50ms each. The standard tone (S) was a sound of 800 Hz lasting 100 ms. Seven healthy volunteers (4 females) participated (age range 22-34 years). We conducted two kinds of experiments (of 880 number trials each), one with passive listening to the stimuli (no-attention condition) and one where subjects tried to distinguish the deviant stimuli (attention condition). We demonstrated MMN waveforms as a negative peak for each condition and deviant, approx. 200ms after onset of the stimulus. Statistical analysis (1-way ANOVA) was performed for the peak latency and amplitude of the MMN for the electrode Fz, for the following four groups: (1) attention, stimulus D2-S (subtraction of averaged curves), (2) no-attention D2-S, (3) attention D1-S, (4) no-attention D1-S. No statistically significant differences were found for the MMN peak latency. The mean MMN peak amplitude was significantly higher for the D1 stimulus in the no-attention D2-S compared to the no-attention D1-S condition (p=0.03). This result can be regarded as an indication that the MMN response is relevant to the complexity and the power of the sound stimulus. Moreover, no statistically different peak MMN value was found between the attention and the no-attention conditions for each sound stimulus. This indicates that the MMN might be related to unconscious mechanisms. Conference: 41st European Brain and Behaviour Society Meeting, Rhodes Island, Greece, 13 Sep - 18 Sep, 2009. Presentation Type: Poster Presentation Topic: Poster presentations Citation: Psiouri G, Stavrinou ML, Koupparis A, Kokkinos V and Kostopoulos GK (2009). Demonstration of MMN in human subjects after stimulation with two complex deviant sounds. Conference Abstract: 41st European Brain and Behaviour Society Meeting. doi: 10.3389/conf.neuro.08.2009.09.264 Copyright: The abstracts in this collection have not been subject to any Frontiers peer review or checks, and are not endorsed by Frontiers. They are made available through the Frontiers publishing platform as a service to conference organizers and presenters. The copyright in the individual abstracts is owned by the author of each abstract or his/her employer unless otherwise stated. Each abstract, as well as the collection of abstracts, are published under a Creative Commons CC-BY 4.0 (attribution) licence (https://creativecommons.org/licenses/by/4.0/) and may thus be reproduced, translated, adapted and be the subject of derivative works provided the authors and Frontiers are attributed. For Frontiers’ terms and conditions please see https://www.frontiersin.org/legal/terms-and-conditions. Received: 12 Jun 2009; Published Online: 12 Jun 2009. * Correspondence: Georgia Psiouri, University of Patras, Department of Physiology, Medical School, Patras, Greece, gpsiouri@yahoo.gr Login Required This action requires you to be registered with Frontiers and logged in. To register or login click here. Abstract Info Abstract The Authors in Frontiers Georgia Psiouri Maria L Stavrinou Andrew Koupparis Vassileios Kokkinos George K Kostopoulos Google Georgia Psiouri Maria L Stavrinou Andrew Koupparis Vassileios Kokkinos George K Kostopoulos Google Scholar Georgia Psiouri Maria L Stavrinou Andrew Koupparis Vassileios Kokkinos George K Kostopoulos PubMed Georgia Psiouri Maria L Stavrinou Andrew Koupparis Vassileios Kokkinos George K Kostopoulos Related Article in Frontiers Google Scholar PubMed Abstract Close Back to top Javascript is disabled. Please enable Javascript in your browser settings in order to see all the content on this page." @default.
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• W39634557 date "2009-01-01" @default.
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• W39634557 title "Demonstration of MMN in human subjects after stimulation with two complex deviant sounds" @default.
• W39634557 doi "https://doi.org/10.3389/conf.neuro.08.2009.09.264" @default.
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