Matches in SemOpenAlex for { <https://semopenalex.org/work/W39828664> ?p ?o ?g. }
Showing items 1 to 92 of
92
with 100 items per page.
- W39828664 endingPage "15" @default.
- W39828664 startingPage "1" @default.
- W39828664 abstract "The principal role of the immune system is to confer protection on the organism against foreign invading pathogens, which can gain access to the body by different routes. The targeted (specific) immune response is generated by the combined interaction of the cellular (T lymphocytes) and humoral responses (B lymphocytes), both coordinated by the production of active substances—the cytokines. Autoimmunity is an organism's immune response against its own cells and tissues, on failure to recognize self-cells. The appearance of tolerance is a key concept in autoimmunity. The immunologic tolerance is preserved by the selection of lymphocytes in the thymus, programmed cell death (apoptosis), and cytokines. The avoidance of immunologic tolerance can lead to autoimmune disease. Autoimmune disease is any disease that results from an aberrant immune response, i.e, autoimmunity. Autoimmune diseases can result from autoantigens, polyclonal activation, aberrant expression of HLA, idiotypes and idiotypic connectivities, hormonal factors, environmental factors, and immunologic factors. There exists an association between autoimmune diseases and neoplasms. Autoimmune phenotype and various autoantibodies have been found in patients with diverse malignancies. The increased tendencies to malignancies are because of genetic factors and environmental determinants (i.e. chemotherapy). Examples of common neoplasms in autoimmune diseases include: lymphoproliferative malignancies in patients with rheumatoid arthritis, lymphomas in patients with SLE and Sjo-gren's syndrome, epithelial malignancies in patients with dermatomyositis and polymyositis, lung cancer in scleroderma and lymphomas, and thyroid papillary carcinomas in patients with autoimmune thyroid diseases." @default.
- W39828664 created "2016-06-24" @default.
- W39828664 creator A5074738902 @default.
- W39828664 creator A5075106701 @default.
- W39828664 date "2000-01-01" @default.
- W39828664 modified "2023-09-25" @default.
- W39828664 title "Introduction: The Immune System, the Autoimmune State and Autoimmune Disease" @default.
- W39828664 cites W122693986 @default.
- W39828664 cites W1967423017 @default.
- W39828664 cites W1971424303 @default.
- W39828664 cites W1984927734 @default.
- W39828664 cites W1989400464 @default.
- W39828664 cites W1990073224 @default.
- W39828664 cites W1992707199 @default.
- W39828664 cites W2001863306 @default.
- W39828664 cites W2010565211 @default.
- W39828664 cites W2040535574 @default.
- W39828664 cites W2041466047 @default.
- W39828664 cites W2051808553 @default.
- W39828664 cites W2053278781 @default.
- W39828664 cites W2055367684 @default.
- W39828664 cites W2061921780 @default.
- W39828664 cites W2063669781 @default.
- W39828664 cites W2068684485 @default.
- W39828664 cites W2109656144 @default.
- W39828664 cites W2116690382 @default.
- W39828664 cites W2117689741 @default.
- W39828664 cites W2123892270 @default.
- W39828664 cites W2159180361 @default.
- W39828664 cites W2160329368 @default.
- W39828664 cites W2169256057 @default.
- W39828664 cites W2180410355 @default.
- W39828664 cites W2227157639 @default.
- W39828664 cites W2319802323 @default.
- W39828664 cites W4376849554 @default.
- W39828664 doi "https://doi.org/10.1016/b978-044450331-2/50002-3" @default.
- W39828664 hasPublicationYear "2000" @default.
- W39828664 type Work @default.
- W39828664 sameAs 39828664 @default.
- W39828664 citedByCount "2" @default.
- W39828664 crossrefType "book-chapter" @default.
- W39828664 hasAuthorship W39828664A5074738902 @default.
- W39828664 hasAuthorship W39828664A5075106701 @default.
- W39828664 hasConcept C159654299 @default.
- W39828664 hasConcept C163764329 @default.
- W39828664 hasConcept C190283241 @default.
- W39828664 hasConcept C203014093 @default.
- W39828664 hasConcept C2777702733 @default.
- W39828664 hasConcept C2778105408 @default.
- W39828664 hasConcept C2778959938 @default.
- W39828664 hasConcept C2779075594 @default.
- W39828664 hasConcept C2780130043 @default.
- W39828664 hasConcept C3031857 @default.
- W39828664 hasConcept C31573885 @default.
- W39828664 hasConcept C55493867 @default.
- W39828664 hasConcept C71924100 @default.
- W39828664 hasConcept C86803240 @default.
- W39828664 hasConcept C8891405 @default.
- W39828664 hasConceptScore W39828664C159654299 @default.
- W39828664 hasConceptScore W39828664C163764329 @default.
- W39828664 hasConceptScore W39828664C190283241 @default.
- W39828664 hasConceptScore W39828664C203014093 @default.
- W39828664 hasConceptScore W39828664C2777702733 @default.
- W39828664 hasConceptScore W39828664C2778105408 @default.
- W39828664 hasConceptScore W39828664C2778959938 @default.
- W39828664 hasConceptScore W39828664C2779075594 @default.
- W39828664 hasConceptScore W39828664C2780130043 @default.
- W39828664 hasConceptScore W39828664C3031857 @default.
- W39828664 hasConceptScore W39828664C31573885 @default.
- W39828664 hasConceptScore W39828664C55493867 @default.
- W39828664 hasConceptScore W39828664C71924100 @default.
- W39828664 hasConceptScore W39828664C86803240 @default.
- W39828664 hasConceptScore W39828664C8891405 @default.
- W39828664 hasLocation W398286641 @default.
- W39828664 hasOpenAccess W39828664 @default.
- W39828664 hasPrimaryLocation W398286641 @default.
- W39828664 hasRelatedWork W107904986 @default.
- W39828664 hasRelatedWork W1981014481 @default.
- W39828664 hasRelatedWork W203897561 @default.
- W39828664 hasRelatedWork W2049181366 @default.
- W39828664 hasRelatedWork W2057968126 @default.
- W39828664 hasRelatedWork W2141301927 @default.
- W39828664 hasRelatedWork W2490460516 @default.
- W39828664 hasRelatedWork W2593968410 @default.
- W39828664 hasRelatedWork W2907025905 @default.
- W39828664 hasRelatedWork W4311075666 @default.
- W39828664 isParatext "false" @default.
- W39828664 isRetracted "false" @default.
- W39828664 magId "39828664" @default.
- W39828664 workType "book-chapter" @default.