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- W40469036 abstract "Communication between nerve cells involves far more than the direct excitation and inhibition of neuronal firing by chemical transmitters. Messengers liberated by neurons or glial cells, along with blood-born hormones, modulate the response properties of nerve cells. Such regulation involves changes in intracellular messengers and also, in some cases, modulation of genomic activity and expression of gene products implicated in nerve cell function. Chemically mediated regulations usually involve intracellular mechanisms but may also depend to a large degree on the responsiveness of membrane receptors. In this chapter we illustrate how monoamines, neuropeptides, and steroid hormones may interact in the central nervous system (CNS) both directly, and indirectly through receptor-receptor modulation. These studies were made possible by the recent development of receptor binding assay methodologies, which have provided us with new interpretations for the interactive mechanisms underlying neuronal communication." @default.
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- W40469036 date "1987-01-01" @default.
- W40469036 modified "2023-09-23" @default.
- W40469036 title "Radioautographic Approaches to the Study of Receptor-Receptor Interactions in the Central Nervous System" @default.
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- W40469036 doi "https://doi.org/10.1007/978-1-349-08949-9_20" @default.
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