Matches in SemOpenAlex for { <https://semopenalex.org/work/W40906348> ?p ?o ?g. }
Showing items 1 to 51 of
51
with 100 items per page.
- W40906348 endingPage "219" @default.
- W40906348 startingPage "216" @default.
- W40906348 abstract "A simple method was developed for the analysis of 6-hydroxy-1-methyl-1,2,3,4-tetrahydro-β-carboline (6-OH-MTHβC), 5-hydroxytryptamine (5-HT) and 5-hydroxyindole acetic acid (5-HIAA) in rat brain by high performance liquid chromatography with electrochemical detection (HPLC-ECD). The separation of the sample was performed on a Discovery HS F5 column (250 mm×4.6 mm,5 μm) with a mobile phase of the buffer (40 mmol/L citric acid+20 mmol/L Na2HPO4+0.3 mmol/L EDTA2Na, pH 4.0)-methanol( 78:22, v/v) at a flow rate of 1.0 mL/min. The electrochemical detector was Coularray Detector-4. This method showed good linearity (r＞0.9992) for the quantification of 6-OH-MTHβC, 5-HT and 5-HIAA in the concentration range of 1.0-500.0 μg/L. The limits of detection were 0.56, 0.26 and 0.53 μg/L, respectively. The recoveries of 6-OH-MTHβC, 5-HT and 5-HIAA spiked in rat brain samples were 87.1%-98.2%, 87.0%-95.3%, 90.1%-97.7%, respectively, and the relative standard deviations of intra-day and inter-day determinations were both less than 6.1%. In comparison with the control, the analysis of alcohol-exposed neonatal rat brain samples revealed a significant difference in the level of 6-OH-MTHβC (P＜0.05). The method was proved to be simple, highly sensitive, and could be applied in the analysis of 6-OH-MTHβC, 5-HT and 5-HIAA in the rat brain." @default.
- W40906348 created "2016-06-24" @default.
- W40906348 creator A5018608686 @default.
- W40906348 creator A5031288832 @default.
- W40906348 creator A5040260303 @default.
- W40906348 creator A5064556747 @default.
- W40906348 creator A5071780556 @default.
- W40906348 date "2009-03-30" @default.
- W40906348 modified "2023-09-23" @default.
- W40906348 title "鼠脑组织中6-羟基－1-甲基－1,2,3,4-四氢－β-咔啉及其相关生物胺的高效液相色谱－电化学检测" @default.
- W40906348 hasPublicationYear "2009" @default.
- W40906348 type Work @default.
- W40906348 sameAs 40906348 @default.
- W40906348 citedByCount "0" @default.
- W40906348 crossrefType "journal-article" @default.
- W40906348 hasAuthorship W40906348A5018608686 @default.
- W40906348 hasAuthorship W40906348A5031288832 @default.
- W40906348 hasAuthorship W40906348A5040260303 @default.
- W40906348 hasAuthorship W40906348A5064556747 @default.
- W40906348 hasAuthorship W40906348A5071780556 @default.
- W40906348 hasConcept C119128265 @default.
- W40906348 hasConcept C178790620 @default.
- W40906348 hasConcept C179998833 @default.
- W40906348 hasConcept C185592680 @default.
- W40906348 hasConcept C2776673659 @default.
- W40906348 hasConcept C2779032678 @default.
- W40906348 hasConcept C2779607525 @default.
- W40906348 hasConcept C2781066024 @default.
- W40906348 hasConcept C43617362 @default.
- W40906348 hasConcept C55493867 @default.
- W40906348 hasConceptScore W40906348C119128265 @default.
- W40906348 hasConceptScore W40906348C178790620 @default.
- W40906348 hasConceptScore W40906348C179998833 @default.
- W40906348 hasConceptScore W40906348C185592680 @default.
- W40906348 hasConceptScore W40906348C2776673659 @default.
- W40906348 hasConceptScore W40906348C2779032678 @default.
- W40906348 hasConceptScore W40906348C2779607525 @default.
- W40906348 hasConceptScore W40906348C2781066024 @default.
- W40906348 hasConceptScore W40906348C43617362 @default.
- W40906348 hasConceptScore W40906348C55493867 @default.
- W40906348 hasIssue "2" @default.
- W40906348 hasLocation W409063481 @default.
- W40906348 hasOpenAccess W40906348 @default.
- W40906348 hasPrimaryLocation W409063481 @default.
- W40906348 hasVolume "27" @default.
- W40906348 isParatext "false" @default.
- W40906348 isRetracted "false" @default.
- W40906348 magId "40906348" @default.
- W40906348 workType "article" @default.