Matches in SemOpenAlex for { <https://semopenalex.org/work/W41017304> ?p ?o ?g. }
- W41017304 endingPage "30" @default.
- W41017304 startingPage "1317" @default.
- W41017304 abstract "Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are well-studied neurotrophins involved in neurogenesis, differentiation, growth, and maintenance of selected peripheral and central populations of neuronal cells during development and adulthood. Neurotrophins, in concert with the hypothalamic-pituitary-adrenal (HPA) axis, play key roles in modulating brain plasticity and behavioral coping, especially during ontogenetic critical periods, when the developing brain is particularly sensitive to external stimuli. Early life events, such as psychophysical stress, affect NGF and BDNF levels and induce dysregulation of the HPA axis, thereby affecting brain development and contributing to inter-individual differences in vulnerability to stress or psychiatric disorders. Immobilization stress modifies BDNF mRNA expression in some organs. We studied the effect of immobilization stress on BDNF and its receptor tyrosine receptor kinase B (TrkB) in rat submandibular glands, and found increased BDNF expression in duct cells under immobilization stress. Upon further investigation on the influence of salivary glands on plasma BDNF using an acute immobilization stress model, we found that acute immobilization stress lasting 60 min significantly increases the plasma BDNF level. However, plasma BDNF elevation is markedly suppressed in bilaterally sialoadenectomized rats. This suggests that salivary glands may be the primary source of plasma BDNF under acute immobilization stress. This report reviews the structure of salivary glands, the role of neurotrophins in salivary glands, and the significance of BDNF in saliva and salivary glands, followed by a summary of the evidence that indicates the relationship between immobilization stress and BDNF expression within salivary glands." @default.
- W41017304 created "2016-06-24" @default.
- W41017304 creator A5003624135 @default.
- W41017304 creator A5049282731 @default.
- W41017304 creator A5068253707 @default.
- W41017304 date "2010-10-01" @default.
- W41017304 modified "2023-09-23" @default.
- W41017304 title "The role of neurotrophins related to stress in saliva and salivary glands." @default.
- W41017304 cites W1251956675 @default.
- W41017304 cites W1501383613 @default.
- W41017304 cites W1526101614 @default.
- W41017304 cites W1527035699 @default.
- W41017304 cites W1540815256 @default.
- W41017304 cites W1625740378 @default.
- W41017304 cites W1894943419 @default.
- W41017304 cites W1964334773 @default.
- W41017304 cites W1966514705 @default.
- W41017304 cites W1967451740 @default.
- W41017304 cites W1968213313 @default.
- W41017304 cites W1969634414 @default.
- W41017304 cites W1970378578 @default.
- W41017304 cites W1972280500 @default.
- W41017304 cites W1973392525 @default.
- W41017304 cites W1974204788 @default.
- W41017304 cites W1978080363 @default.
- W41017304 cites W1980166225 @default.
- W41017304 cites W1980229159 @default.
- W41017304 cites W1981870344 @default.
- W41017304 cites W1992014747 @default.
- W41017304 cites W1992026473 @default.
- W41017304 cites W1992424513 @default.
- W41017304 cites W1997637503 @default.
- W41017304 cites W1998197647 @default.
- W41017304 cites W1999128166 @default.
- W41017304 cites W1999871144 @default.
- W41017304 cites W2000540402 @default.
- W41017304 cites W2002512748 @default.
- W41017304 cites W2003651391 @default.
- W41017304 cites W2004107819 @default.
- W41017304 cites W2004509498 @default.
- W41017304 cites W2006227380 @default.
- W41017304 cites W2006630143 @default.
- W41017304 cites W2006923280 @default.
- W41017304 cites W2007507642 @default.
- W41017304 cites W2009918823 @default.
- W41017304 cites W2010050518 @default.
- W41017304 cites W2010067104 @default.
- W41017304 cites W2010087296 @default.
- W41017304 cites W2010269783 @default.
- W41017304 cites W2011936466 @default.
- W41017304 cites W2016617827 @default.
- W41017304 cites W2022388170 @default.
- W41017304 cites W2023620805 @default.
- W41017304 cites W2024917768 @default.
- W41017304 cites W2026004048 @default.
- W41017304 cites W2027842829 @default.
- W41017304 cites W2027872382 @default.
- W41017304 cites W2030952413 @default.
- W41017304 cites W2031358273 @default.
- W41017304 cites W2033367566 @default.
- W41017304 cites W2034637320 @default.
- W41017304 cites W2038471328 @default.
- W41017304 cites W2038650940 @default.
- W41017304 cites W2039412763 @default.
- W41017304 cites W2040170605 @default.
- W41017304 cites W2041702995 @default.
- W41017304 cites W2044047843 @default.
- W41017304 cites W2044183295 @default.
- W41017304 cites W2045355179 @default.
- W41017304 cites W2049920605 @default.
- W41017304 cites W2050096256 @default.
- W41017304 cites W2050887398 @default.
- W41017304 cites W2051197860 @default.
- W41017304 cites W2053484819 @default.
- W41017304 cites W2055381771 @default.
- W41017304 cites W2056518522 @default.
- W41017304 cites W2061081311 @default.
- W41017304 cites W2063695629 @default.
- W41017304 cites W2063898145 @default.
- W41017304 cites W2064010258 @default.
- W41017304 cites W2065594917 @default.
- W41017304 cites W2069527370 @default.
- W41017304 cites W2072438363 @default.
- W41017304 cites W2073495772 @default.
- W41017304 cites W2073722064 @default.
- W41017304 cites W2076717018 @default.
- W41017304 cites W2078880078 @default.
- W41017304 cites W2083253299 @default.
- W41017304 cites W2083334137 @default.
- W41017304 cites W2085567491 @default.
- W41017304 cites W2085931944 @default.
- W41017304 cites W2087753402 @default.
- W41017304 cites W2092165212 @default.
- W41017304 cites W2094170571 @default.
- W41017304 cites W2104426891 @default.
- W41017304 cites W2106855106 @default.
- W41017304 cites W2108805072 @default.
- W41017304 cites W2110132051 @default.