FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W41076960> ?p ?o ?g. }

• W41076960 abstract "textabstractAt present, Parkinson's disease (PO), after Alzheimer's disease, is generallyconsidered to be the most frequent progressive neurodegenerative disease in theelderly. Due to the growing proportion of elderly in many populations, more and morepersons will be affected by this disabling disease which constitutes a large burden toman and society. Since the publication of James Parkinson's essay, almost twocenturies have elapsed and, in spite of numerous efforts to unravel the nature of thedisease, the etiology of PO is still unknown. Yet, the neuropathologic and biochemicalchanges that cause the signs of the disease seem to be settled, based on knowledge that was mainly accumulated in only the past three decades. Neuropathologically, POis defined by selective degeneration of pigmented neurons of the pars compacta ofthe substantia nigra and other brainstem ganglia, with cytoplasmic inclusions, calledLewy bodies, in the surviving neurons as the hallmark. These lesions lead to adeficiency of striatal dopamine. It is now considered that parkinsonian signs onlybecome clinically overt after dopaminergic cell loss of approximately 50% and thatat that moment the endogeneous dopamine content is depleted by 80%." @default.
• W41076960 created "2016-06-24" @default.
• W41076960 creator A5081277061 @default.
• W41076960 date "1997-09-10" @default.
• W41076960 modified "2023-09-22" @default.
• W41076960 title "Epidemiology of Parkinson's Disease: The Rotterdam Study" @default.
• W41076960 cites W113466445 @default.
• W41076960 cites W119618776 @default.
• W41076960 cites W1238680464 @default.
• W41076960 cites W1506736245 @default.
• W41076960 cites W1556008598 @default.
• W41076960 cites W1562359367 @default.
• W41076960 cites W1599621040 @default.
• W41076960 cites W1820596764 @default.
• W41076960 cites W1892055067 @default.
• W41076960 cites W1963756656 @default.
• W41076960 cites W1965236557 @default.
• W41076960 cites W1965776676 @default.
• W41076960 cites W1965927800 @default.
• W41076960 cites W1966243341 @default.
• W41076960 cites W1966798983 @default.
• W41076960 cites W1969045963 @default.
• W41076960 cites W1969611978 @default.
• W41076960 cites W1970534639 @default.
• W41076960 cites W1971947310 @default.
• W41076960 cites W1975040518 @default.
• W41076960 cites W1977314903 @default.
• W41076960 cites W1977817124 @default.
• W41076960 cites W1977917379 @default.
• W41076960 cites W1979881519 @default.
• W41076960 cites W1982060705 @default.
• W41076960 cites W1982164956 @default.
• W41076960 cites W1982173583 @default.
• W41076960 cites W1983178060 @default.
• W41076960 cites W1983366580 @default.
• W41076960 cites W1985613988 @default.
• W41076960 cites W1986776141 @default.
• W41076960 cites W1987446689 @default.
• W41076960 cites W1988987018 @default.
• W41076960 cites W1993071155 @default.
• W41076960 cites W1993253047 @default.
• W41076960 cites W1994172268 @default.
• W41076960 cites W1994291413 @default.
• W41076960 cites W1995972594 @default.
• W41076960 cites W1996001974 @default.
• W41076960 cites W1997022625 @default.
• W41076960 cites W1998100748 @default.
• W41076960 cites W2000628620 @default.
• W41076960 cites W2000768299 @default.
• W41076960 cites W2000790818 @default.
• W41076960 cites W2001253835 @default.
• W41076960 cites W2001789751 @default.
• W41076960 cites W2003861040 @default.
• W41076960 cites W2004818860 @default.
• W41076960 cites W2006409771 @default.
• W41076960 cites W2007316513 @default.
• W41076960 cites W2007465823 @default.
• W41076960 cites W2007891209 @default.
• W41076960 cites W2008309472 @default.
• W41076960 cites W2008560062 @default.
• W41076960 cites W2009804051 @default.
• W41076960 cites W2011991078 @default.
• W41076960 cites W2013240203 @default.
• W41076960 cites W2013407711 @default.
• W41076960 cites W2013826930 @default.
• W41076960 cites W2014119534 @default.
• W41076960 cites W2015200601 @default.
• W41076960 cites W201588874 @default.
• W41076960 cites W2017453645 @default.
• W41076960 cites W2017540053 @default.
• W41076960 cites W2017923539 @default.
• W41076960 cites W2020232311 @default.
• W41076960 cites W2020753791 @default.
• W41076960 cites W2021069712 @default.
• W41076960 cites W2021181758 @default.
• W41076960 cites W2022617930 @default.
• W41076960 cites W2024377399 @default.
• W41076960 cites W2025931289 @default.
• W41076960 cites W2026362532 @default.
• W41076960 cites W2027309632 @default.
• W41076960 cites W2027943861 @default.
• W41076960 cites W2028064682 @default.
• W41076960 cites W2028499340 @default.
• W41076960 cites W2029239144 @default.
• W41076960 cites W2030227417 @default.
• W41076960 cites W2030802264 @default.
• W41076960 cites W2031651686 @default.
• W41076960 cites W2032484012 @default.
• W41076960 cites W2033118794 @default.
• W41076960 cites W2033624890 @default.
• W41076960 cites W2034067256 @default.
• W41076960 cites W2035257443 @default.
• W41076960 cites W2038483650 @default.
• W41076960 cites W2038573022 @default.
• W41076960 cites W2039041773 @default.
• W41076960 cites W2039727503 @default.
• W41076960 cites W204017299 @default.
• W41076960 cites W2041550755 @default.
• W41076960 cites W2041694263 @default.
• W41076960 cites W2043625003 @default.

• next