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- W41298516 abstract "The present overview is charactzerized by the detailed description of two systems between which the bridge is still swaying and not well defined: tight junction molecules of brain microvessel endothelial cells representing the barrier proper and nonendothelial and extracellular molecules, which are responsible for the regulation of angiogenesis, cell migration, and maintenance of the endothelial barrier. Both systems are extremely complicated sui generis and increase their complexity by a cross talk, which, however, is poorly understood at present. Nobody knows the differential impact leading to barrier commitment, and nothing is known about the links between extracellular matrix and barrier regulation, the pathway from integrins to the claudins, or the precise role of astrocytes or astrocytoma cells in barrier formation or dysregulation, respectively. There is no doubt that the molecular analysis of the blood–brain barrier is of outstanding clinical relevance, as insight into regulatory mechanisms of the paracellular barrier in the brain is of primary significance for the development of new therapeutic strategies. Treatment of brain tumors has to consider both tumor angiogenesis and the permeability of tumor vessels. Both are intimately dependent on the brain microenvironment, and in future research the analysis of this microenvironment will be the greatest challenge in understanding the blood–brain barrier in health and disease." @default.
- W41298516 created "2016-06-24" @default.
- W41298516 creator A5012957761 @default.
- W41298516 creator A5028953672 @default.
- W41298516 creator A5051007456 @default.
- W41298516 date "2004-01-01" @default.
- W41298516 modified "2023-09-24" @default.
- W41298516 title "The Blood–Brain Barrier in the Human Glioma" @default.
- W41298516 cites W1495656315 @default.
- W41298516 cites W1505791606 @default.
- W41298516 cites W1513774612 @default.
- W41298516 cites W1522674317 @default.
- W41298516 cites W1557303431 @default.
- W41298516 cites W1573055043 @default.
- W41298516 cites W1576290062 @default.
- W41298516 cites W1606934029 @default.
- W41298516 cites W1790932677 @default.
- W41298516 cites W1796054280 @default.
- W41298516 cites W1831896296 @default.
- W41298516 cites W1877348036 @default.
- W41298516 cites W1886431664 @default.
- W41298516 cites W1897118574 @default.
- W41298516 cites W1924595537 @default.
- W41298516 cites W1926301789 @default.
- W41298516 cites W1936651842 @default.
- W41298516 cites W1964062608 @default.
- W41298516 cites W1967001670 @default.
- W41298516 cites W1969321129 @default.
- W41298516 cites W1969434689 @default.
- W41298516 cites W1969986988 @default.
- W41298516 cites W1973893754 @default.
- W41298516 cites W1975939265 @default.
- W41298516 cites W1976936511 @default.
- W41298516 cites W1977183609 @default.
- W41298516 cites W1977940746 @default.
- W41298516 cites W1981850472 @default.
- W41298516 cites W1982974412 @default.
- W41298516 cites W1984284981 @default.
- W41298516 cites W1984587620 @default.
- W41298516 cites W1985083844 @default.
- W41298516 cites W1986085718 @default.
- W41298516 cites W1986758971 @default.
- W41298516 cites W1988780041 @default.
- W41298516 cites W1990415925 @default.
- W41298516 cites W1991458538 @default.
- W41298516 cites W1991680358 @default.
- W41298516 cites W1992557354 @default.
- W41298516 cites W1993827474 @default.
- W41298516 cites W1997449859 @default.
- W41298516 cites W1997481445 @default.
- W41298516 cites W1997817173 @default.
- W41298516 cites W1999360913 @default.
- W41298516 cites W1999465006 @default.
- W41298516 cites W2000334999 @default.
- W41298516 cites W2000441131 @default.
- W41298516 cites W2000771735 @default.
- W41298516 cites W2003390216 @default.
- W41298516 cites W2007489238 @default.
- W41298516 cites W2007675851 @default.
- W41298516 cites W2008031109 @default.
- W41298516 cites W2009267287 @default.
- W41298516 cites W2010641543 @default.
- W41298516 cites W2011583083 @default.
- W41298516 cites W2013458878 @default.
- W41298516 cites W2016753320 @default.
- W41298516 cites W2022219701 @default.
- W41298516 cites W2023118456 @default.
- W41298516 cites W2023353150 @default.
- W41298516 cites W2024872254 @default.
- W41298516 cites W2025658823 @default.
- W41298516 cites W2026108180 @default.
- W41298516 cites W2026695355 @default.
- W41298516 cites W2026851415 @default.
- W41298516 cites W2027216690 @default.
- W41298516 cites W2029790299 @default.
- W41298516 cites W2030715083 @default.
- W41298516 cites W2031096207 @default.
- W41298516 cites W2031759209 @default.
- W41298516 cites W2031814288 @default.
- W41298516 cites W2032294682 @default.
- W41298516 cites W2034626424 @default.
- W41298516 cites W2039579271 @default.
- W41298516 cites W2040509610 @default.
- W41298516 cites W2041630140 @default.
- W41298516 cites W2041708400 @default.
- W41298516 cites W2042094805 @default.
- W41298516 cites W2042652697 @default.
- W41298516 cites W2043247007 @default.
- W41298516 cites W2043249951 @default.
- W41298516 cites W2044800165 @default.
- W41298516 cites W2046678465 @default.
- W41298516 cites W2047746754 @default.
- W41298516 cites W2048185125 @default.
- W41298516 cites W2049327035 @default.
- W41298516 cites W2051425293 @default.
- W41298516 cites W2052804176 @default.
- W41298516 cites W2052824223 @default.
- W41298516 cites W2053135410 @default.