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- W41323986 abstract "The activation of the immune system by oxidized phospholipids plays an important role in the process of developing atherosclerosis. The measurement of oxidized low density lipoproteins (oxLDL)-Ab could be used to investigate immune responses in vivo. It is known that spontaneous oxidation of LDL, as well as use of different batches of LDL possessing different susceptibilities to oxidation, leads to variations in the estimation of autoantibody concentrations. Synthesized oxPAPC might be a novel antigen to use for measurement of oxidized 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine (oxPAPC) autoantibodies. Detection of oxPAPC-Ab could serve as an autoimmune marker for diagnosis of atherosclerosis, and could suggest patients for whom anti-oxidant therapy might be appropriate. The pathophysiologic significance and natural mechanism of action of oxPAPC autoantibodies requires further investigation." @default.
- W41323986 created "2016-06-24" @default.
- W41323986 creator A5072790142 @default.
- W41323986 date "2001-01-01" @default.
- W41323986 modified "2023-09-27" @default.
- W41323986 title "Autoantibodies Against Oxidized Palmitoyl Arachidonoyl Phosphocholine in Atherosclerosis" @default.
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- W41323986 doi "https://doi.org/10.1016/b978-044450669-6/50016-5" @default.
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