FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W41329518> ?p ?o ?g. }

• W41329518 endingPage "225" @default.
• W41329518 startingPage "219" @default.
• W41329518 abstract "The transfer of free cholesterol from [3H]cholesterol-labelled plasma lipoproteins to cultured human lung fibroblasts was studied in a serum-free medium. The uptake of [3H]cholesterol depended upon time of incubation, concentration of lipoprotein in the medium, and temperature. Modified (reduced and methylated) low-density lipoprotein (LDL), which did not enter the cells by the receptor pathway, gave a somewhat lower transfer rate than unmodified LDL, but if the transfer values for native LDL were corrected for the receptor-mediated uptake of cholesterol the difference was eliminated. The initial rates of transfer of [3H]cholesterol from LDL and high-density lipoprotein (HDL) were of the same order of magnitude (0.67 +/- 0.05 and 0.75 +/- 0.06 nmol of cholesterol/h per mg of cell protein, respectively) while that from very-low-density lipoprotein (VLDL) was much lower (0.23 +/- 0.02 nmol of cholesterol/h per mg) (means +/- S.D., n = 5). The activation energy for transfer of cholesterol from reduced, methylated LDL to fibroblasts was determined to be 57.5 kJ/mol. If albumin was added to the incubation medium the transfer of [3H]cholesterol was enhanced, while that of [14C]dipalmitoyl phosphatidylcholine was decreased compared with the protein-free system. The results demonstrate that, in spite of its low water solubility, free cholesterol can move from lipoproteins to cellular membranes, probably by aqueous diffusion. We propose that physicochemical transfer of free cholesterol may be a significant mechanism for net uptake of the sterol into the artery during atherogenesis." @default.
• W41329518 created "2016-06-24" @default.
• W41329518 creator A5016194789 @default.
• W41329518 creator A5084790244 @default.
• W41329518 date "1985-05-15" @default.
• W41329518 modified "2023-10-18" @default.
• W41329518 title "Physicochemical transfer of [3H]cholesterol from plasma lipoproteins to cultured human fibroblasts" @default.
• W41329518 cites W1484316354 @default.
• W41329518 cites W1513897103 @default.
• W41329518 cites W1558567754 @default.
• W41329518 cites W1593616284 @default.
• W41329518 cites W1893943578 @default.
• W41329518 cites W1969068329 @default.
• W41329518 cites W1970013164 @default.
• W41329518 cites W1974761435 @default.
• W41329518 cites W1976967663 @default.
• W41329518 cites W1985711398 @default.
• W41329518 cites W1986234679 @default.
• W41329518 cites W1989476508 @default.
• W41329518 cites W2000225343 @default.
• W41329518 cites W2008382496 @default.
• W41329518 cites W2009763688 @default.
• W41329518 cites W2019716227 @default.
• W41329518 cites W2024423766 @default.
• W41329518 cites W2029812497 @default.
• W41329518 cites W2031423487 @default.
• W41329518 cites W2032731208 @default.
• W41329518 cites W2041242656 @default.
• W41329518 cites W2043483779 @default.
• W41329518 cites W2056027724 @default.
• W41329518 cites W2058471523 @default.
• W41329518 cites W2065031942 @default.
• W41329518 cites W2072983541 @default.
• W41329518 cites W2074880885 @default.
• W41329518 cites W2080644290 @default.
• W41329518 cites W2091015159 @default.
• W41329518 cites W2097174011 @default.
• W41329518 cites W2113504642 @default.
• W41329518 cites W2125914065 @default.
• W41329518 cites W2167890969 @default.
• W41329518 cites W2187146142 @default.
• W41329518 cites W2347061855 @default.
• W41329518 cites W2409024158 @default.
• W41329518 cites W2410705738 @default.
• W41329518 cites W2413788987 @default.
• W41329518 cites W2418434937 @default.
• W41329518 cites W2593134712 @default.
• W41329518 doi "https://doi.org/10.1042/bj2280219" @default.
• W41329518 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/1144972" @default.
• W41329518 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2988515" @default.
• W41329518 hasPublicationYear "1985" @default.
• W41329518 type Work @default.
• W41329518 sameAs 41329518 @default.
• W41329518 citedByCount "16" @default.
• W41329518 crossrefType "journal-article" @default.
• W41329518 hasAuthorship W41329518A5016194789 @default.
• W41329518 hasAuthorship W41329518A5084790244 @default.
• W41329518 hasBestOaLocation W413295182 @default.
• W41329518 hasConcept C110459506 @default.
• W41329518 hasConcept C126322002 @default.
• W41329518 hasConcept C134018914 @default.
• W41329518 hasConcept C185592680 @default.
• W41329518 hasConcept C25642318 @default.
• W41329518 hasConcept C2776330855 @default.
• W41329518 hasConcept C2778163477 @default.
• W41329518 hasConcept C2778718757 @default.
• W41329518 hasConcept C2778918659 @default.
• W41329518 hasConcept C2779620165 @default.
• W41329518 hasConcept C2780072125 @default.
• W41329518 hasConcept C41625074 @default.
• W41329518 hasConcept C55493867 @default.
• W41329518 hasConcept C71924100 @default.
• W41329518 hasConcept C8004288 @default.
• W41329518 hasConcept C8243546 @default.
• W41329518 hasConcept C86803240 @default.
• W41329518 hasConceptScore W41329518C110459506 @default.
• W41329518 hasConceptScore W41329518C126322002 @default.
• W41329518 hasConceptScore W41329518C134018914 @default.
• W41329518 hasConceptScore W41329518C185592680 @default.
• W41329518 hasConceptScore W41329518C25642318 @default.
• W41329518 hasConceptScore W41329518C2776330855 @default.
• W41329518 hasConceptScore W41329518C2778163477 @default.
• W41329518 hasConceptScore W41329518C2778718757 @default.
• W41329518 hasConceptScore W41329518C2778918659 @default.
• W41329518 hasConceptScore W41329518C2779620165 @default.
• W41329518 hasConceptScore W41329518C2780072125 @default.
• W41329518 hasConceptScore W41329518C41625074 @default.
• W41329518 hasConceptScore W41329518C55493867 @default.
• W41329518 hasConceptScore W41329518C71924100 @default.
• W41329518 hasConceptScore W41329518C8004288 @default.
• W41329518 hasConceptScore W41329518C8243546 @default.
• W41329518 hasConceptScore W41329518C86803240 @default.
• W41329518 hasIssue "1" @default.
• W41329518 hasLocation W413295181 @default.
• W41329518 hasLocation W413295182 @default.
• W41329518 hasLocation W413295183 @default.
• W41329518 hasLocation W413295184 @default.
• W41329518 hasOpenAccess W41329518 @default.

• next