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- W41441050 endingPage "327" @default.
- W41441050 startingPage "279" @default.
- W41441050 abstract "This chapter discusses the effect of chemical and physical agents on brain cholesterol. The brain represents the largest repository of body cholesterol however relatively little is known about its metabolism and even less about its function and role within the central nervous system. It has been suggested that cholesterol turnover may be more rapid in some areas than in others. In view of new evidence that indicates both biosynthetic capacity and turnover ability of cholesterol in adult brain, studies dealing with the effect of chemical and physical agents on the constituent have become more rational. That the stability of brain cholesterol was so readily accepted in view of early experiments showing drug effect is difficult to comprehend. Drug stimulants and drug depressants may have their mechanism of action directly or indirectly on brain cholesterol. It is clear from the diversity of chemical structures which affect cholesterol metabolism in general and brain cholesterol in particular that further work will be necessary to relate the mechanisms of drug action on brain cholesterol and brain function." @default.
- W41441050 created "2016-06-24" @default.
- W41441050 creator A5007347950 @default.
- W41441050 date "1967-01-01" @default.
- W41441050 modified "2023-10-04" @default.
- W41441050 title "Brain Cholesterol: The Effect of Chemical and Physical Agents" @default.
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