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- W41644586 abstract "This chapter reviews the gross and microscopic alterations occurring in the pancreases of diabetic patients. The chapter discusses the historical development of recognition of these changes and describes their place within the framework of the modern concept of the pathophysiology of human diabetes. The etiology of diabetes is heterogeneous. Its manifestations are produced by a number of factors of which only some are known. The disease has its roots in extrapancreatic alterations such as hyperthyroidism, cortical or medullary adrenal diseases or hyperplasia or tumors of the anterior pituitary gland. In most diabetic patients, the etiology of the disease remains obscure, and it is to this large group of cases that the term idiopathic diabetes has been applied. Depending upon the age of onset and on the clinical manifestations, two types of diabetes are distinguished: (1) the juvenile, or growth-onset, and (2) the adult, or maturity-onset. The metabolic disturbances of diabetes mellitus may not only be the result of relative or absolute insulin deficiency but may also require the presence of glucagon." @default.
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- W41644586 date "1978-01-01" @default.
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- W41644586 title "The Pancreas in Idiopathic Diabetes§ §The subject of this article is discussed more extensively in Volk and Wellmann (1977)." @default.
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- W41644586 doi "https://doi.org/10.1016/b978-0-12-027309-6.50022-7" @default.
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