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- W41812079 abstract "Clinical studies have demonstrated consistently that diets high in monounsaturated (MUFA) and low in saturated fatty acids (SFA) lower total cholesterol and low density lipoprotein cholesterol (LDL-C) as effectively as lower-fat, low SFA diets. Avocados are a good source of MUFA and also are rich in vitamins, minerals and phytosterols which could beneficially affect CVD risk. A randomized, 3-period cross-over, controlled feeding study was designed to evaluate the effects of avocados on established and emerging risk factors for CVD. Overweight and obese (BMI 25–35 kg/m2) men and women with moderately elevated LDL-C (25 – 90th) will consume 3 treatment diets with a 2 week run-in Western diet. Treatment diets are matched for SFA (<7% energy) and include a low-fat diet (LF: 24% fat, 12% MUFA), a moderate fat diet (MF: 34% fat, 18% MUFA), and a moderate fat diet providing 1 avocado per day (AV: 34% fat, 18% MUFA) with the equivalent fatty acid profile of the MF diet. We hypothesize that the inclusion of 1 avocado per day in a cholesterol-lowering moderate fat diet will improve CVD risk factors including lipids, lipoproteins, markers of oxidative stress and inflammation, and improve reverse cholesterol transport compared to a heart-healthy low fat diet and a moderate fat diet without avocado. This study is supported by the Hass Avocado Board of California. ClincalTrials.gov identifier: NCT0123582" @default.
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- W41812079 date "2011-04-01" @default.
- W41812079 modified "2023-09-22" @default.
- W41812079 title "The effect of one avocado per day on established and emerging cardiovascular disease (CVD) risk factors: study design" @default.
- W41812079 doi "https://doi.org/10.1096/fasebj.25.1_supplement.971.5" @default.
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