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• W418406896 abstract "Ca(2+)-dependent synaptic vesicle recycling is essential for structural homeostasis of synapses and maintenance of neurotransmission. Although, the executive role of intrasynaptic Ca(2+) transients in synaptic vesicle exocytosis is well established, identifying the exact role of Ca(2+) in endocytosis has been difficult. In some studies, Ca(2+) has been suggested as an essential trigger required to initiate synaptic vesicle retrieval, whereas others manipulating synaptic Ca(2+) concentrations reported a modulatory role for Ca(2+) leading to inhibition or acceleration of endocytosis. Molecular studies of synaptic vesicle endocytosis, on the other hand, have consistently focused on the roles of Ca(2+)-calmodulin dependent phosphatase calcineurin and synaptic vesicle protein synaptotagmin as potential Ca(2+) sensors for endocytosis. Most studies probing the role of Ca(2+) in endocytosis have relied on measurements of synaptic vesicle retrieval after strong stimulation. Strong stimulation paradigms elicit fusion and retrieval of multiple synaptic vesicles and therefore can be affected by several factors besides the kinetics and duration of Ca(2+) signals that include the number of exocytosed vesicles and accumulation of released neurotransmitters thus altering fusion and retrieval processes indirectly via retrograde signaling. Studies monitoring single synaptic vesicle endocytosis may help resolve this conundrum as in these settings the impact of Ca(2+) on synaptic fusion probability can be uncoupled from its putative role on synaptic vesicle retrieval. Future experiments using these single vesicle approaches will help dissect the specific role(s) of Ca(2+) and its sensors in synaptic vesicle endocytosis." @default.
• W418406896 created "2016-06-24" @default.
• W418406896 creator A5023569910 @default.
• W418406896 creator A5059395438 @default.
• W418406896 date "2016-07-09" @default.
• W418406896 modified "2023-09-30" @default.
• W418406896 title "Ca²⁺ Dependence of Synaptic Vesicle Endocytosis" @default.
• W418406896 cites W139148589 @default.
• W418406896 cites W1498241934 @default.
• W418406896 cites W1562455864 @default.
• W418406896 cites W1564650596 @default.
• W418406896 cites W1573332568 @default.
• W418406896 cites W1574776511 @default.
• W418406896 cites W1595601862 @default.
• W418406896 cites W1720280203 @default.
• W418406896 cites W1857966900 @default.
• W418406896 cites W1964008139 @default.
• W418406896 cites W1967302106 @default.
• W418406896 cites W1970249565 @default.
• W418406896 cites W1972322271 @default.
• W418406896 cites W1981344194 @default.
• W418406896 cites W1982822685 @default.
• W418406896 cites W1989364196 @default.
• W418406896 cites W1995408976 @default.
• W418406896 cites W1997116271 @default.
• W418406896 cites W2001011427 @default.
• W418406896 cites W2001759117 @default.
• W418406896 cites W2002418745 @default.
• W418406896 cites W2006999571 @default.
• W418406896 cites W2007461061 @default.
• W418406896 cites W2008643711 @default.
• W418406896 cites W2013738253 @default.
• W418406896 cites W2013902743 @default.
• W418406896 cites W2015011519 @default.
• W418406896 cites W2016166286 @default.
• W418406896 cites W2018264391 @default.
• W418406896 cites W2027028077 @default.
• W418406896 cites W2028316115 @default.
• W418406896 cites W2035149692 @default.
• W418406896 cites W2035336615 @default.
• W418406896 cites W2036379080 @default.
• W418406896 cites W2036402923 @default.
• W418406896 cites W2038153199 @default.
• W418406896 cites W2045202254 @default.
• W418406896 cites W2047338538 @default.
• W418406896 cites W2047562589 @default.
• W418406896 cites W2050827241 @default.
• W418406896 cites W2060384627 @default.
• W418406896 cites W2063618791 @default.
• W418406896 cites W2063912923 @default.
• W418406896 cites W2065967745 @default.
• W418406896 cites W2068493233 @default.
• W418406896 cites W2069536209 @default.
• W418406896 cites W2073125666 @default.
• W418406896 cites W2073357387 @default.
• W418406896 cites W2081079441 @default.
• W418406896 cites W2093450191 @default.
• W418406896 cites W2096681544 @default.
• W418406896 cites W2098703603 @default.
• W418406896 cites W2103463163 @default.
• W418406896 cites W2118332945 @default.
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• W418406896 cites W2122247317 @default.
• W418406896 cites W2123355036 @default.
• W418406896 cites W2132653427 @default.
• W418406896 cites W2133521893 @default.
• W418406896 cites W2135719485 @default.
• W418406896 cites W2141022591 @default.
• W418406896 cites W2144107809 @default.
• W418406896 cites W2146529473 @default.
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• W418406896 cites W2153309256 @default.
• W418406896 cites W2153492531 @default.
• W418406896 cites W2159090966 @default.
• W418406896 cites W2160179934 @default.
• W418406896 cites W2162063615 @default.
• W418406896 cites W2163139372 @default.
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• W418406896 doi "https://doi.org/10.1177/1073858415588265" @default.
• W418406896 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25998187" @default.
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