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- W41916706 abstract "Objective To investigate the effects of oxymatrine on cell proliferation and syntheses of TGF-β1 and α-SMA in human mesangial cells. Methods On the human mesangial cells cultured in vitro, MTT assay was used to assess cell proliferation, immunohistochemical staining was conducted to determine the syntheses of TGF-β1 and α-SMA under the effect of oxymatrine. Results Certain concentration of oxymatrine was found to have marked enhancing effect on cell proliferation (P＜0.05), inhibitng effect on the synthesis of TGF-β1 (P＜0.05), but no effect on the synthesis of α-SMA (P＞0.05). Conclusion Certain concentration of oxymatrine can inhibit kidney fibrosis and protect mesangial cells, but have no effect on the phenotype of mesangial cells." @default.
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- W41916706 date "2007-03-25" @default.
- W41916706 modified "2023-09-28" @default.
- W41916706 title "苦参素对肾小球系膜细胞增殖及TGF-β1、α-SMA合成的影响" @default.
- W41916706 hasPublicationYear "2007" @default.
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