Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200001063> ?p ?o ?g. }
- W4200001063 endingPage "588" @default.
- W4200001063 startingPage "566" @default.
- W4200001063 abstract "The effect of sensory deprivation on anatomical and physiological properties in two genetically defined types of layer 6 corticothalamic pyramidal cells in mouse somatosensory barrel cortex was investigated using in vitro electrophysiology. The two types analysed were the L6-Ntsr1 subtype, found preferentially in the upper region of layer 6 and projecting to both ventral posterior medial nucleus of the thalamus and posterior medial nucleus of the thalamus, and the L6-Drd1a subtype, located mostly in the lower regions of layer 6 and projecting to posterior medial nucleus. We found that the apical dendrite in L6-Ntsr1 cells is longer and more branched, compared with L6-Drd1a cells, and that the increase in firing frequency with increasing current stimulation is steeper in L6-Drd1a cells. Sensory deprivation was achieved clipping one row of whiskers from birth until the day of experiment (16 ± 2 days). Mice of this age are actively exploring. In L6-Ntsr1, but not in L6-Drd1a cells, sensory deprivation decreased apical and basal dendrite outgrowth, and calcium influx evoked by backpropagating action potentials. These results contribute to the ongoing functional characterisation of corticothalamic layer 6 cells and indicate differences in the postnatal cortical refinement of two distinct corticothalamic circuits." @default.
- W4200001063 created "2021-12-31" @default.
- W4200001063 creator A5024360840 @default.
- W4200001063 creator A5049280311 @default.
- W4200001063 date "2022-01-01" @default.
- W4200001063 modified "2023-10-06" @default.
- W4200001063 title "Sensory deprivation leads to subpopulation‐specific changes in layer 6 corticothalamic cells" @default.
- W4200001063 cites W1434539459 @default.
- W4200001063 cites W1580480836 @default.
- W4200001063 cites W1880079596 @default.
- W4200001063 cites W1974138775 @default.
- W4200001063 cites W1975341445 @default.
- W4200001063 cites W1977258830 @default.
- W4200001063 cites W1979258934 @default.
- W4200001063 cites W1987261355 @default.
- W4200001063 cites W1987332330 @default.
- W4200001063 cites W1993936506 @default.
- W4200001063 cites W1999576398 @default.
- W4200001063 cites W2003474735 @default.
- W4200001063 cites W2010244379 @default.
- W4200001063 cites W2014300374 @default.
- W4200001063 cites W2021712643 @default.
- W4200001063 cites W2026904474 @default.
- W4200001063 cites W2029513180 @default.
- W4200001063 cites W2037022173 @default.
- W4200001063 cites W2045933100 @default.
- W4200001063 cites W2046696258 @default.
- W4200001063 cites W2057426891 @default.
- W4200001063 cites W2058962245 @default.
- W4200001063 cites W2065416066 @default.
- W4200001063 cites W2073110077 @default.
- W4200001063 cites W2080865416 @default.
- W4200001063 cites W2082333529 @default.
- W4200001063 cites W2084155385 @default.
- W4200001063 cites W2091111430 @default.
- W4200001063 cites W2101586252 @default.
- W4200001063 cites W2106235427 @default.
- W4200001063 cites W2108809409 @default.
- W4200001063 cites W2109471230 @default.
- W4200001063 cites W2109827560 @default.
- W4200001063 cites W2109839589 @default.
- W4200001063 cites W2113827256 @default.
- W4200001063 cites W2114120698 @default.
- W4200001063 cites W2134115602 @default.
- W4200001063 cites W2135137274 @default.
- W4200001063 cites W2136446423 @default.
- W4200001063 cites W2149171047 @default.
- W4200001063 cites W2151103686 @default.
- W4200001063 cites W2156379733 @default.
- W4200001063 cites W2157616236 @default.
- W4200001063 cites W2161064560 @default.
- W4200001063 cites W2165526058 @default.
- W4200001063 cites W2258993652 @default.
- W4200001063 cites W2292633064 @default.
- W4200001063 cites W2335883707 @default.
- W4200001063 cites W2405754533 @default.
- W4200001063 cites W2490300743 @default.
- W4200001063 cites W2520155421 @default.
- W4200001063 cites W2528796502 @default.
- W4200001063 cites W2767609314 @default.
- W4200001063 cites W2771661168 @default.
- W4200001063 cites W2782122695 @default.
- W4200001063 cites W2782751937 @default.
- W4200001063 cites W2785260965 @default.
- W4200001063 cites W2789981464 @default.
- W4200001063 cites W2800617744 @default.
- W4200001063 cites W2801704011 @default.
- W4200001063 cites W3011904776 @default.
- W4200001063 cites W3040667808 @default.
- W4200001063 cites W3120243742 @default.
- W4200001063 doi "https://doi.org/10.1111/ejn.15572" @default.
- W4200001063 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34927292" @default.
- W4200001063 hasPublicationYear "2022" @default.
- W4200001063 type Work @default.
- W4200001063 citedByCount "2" @default.
- W4200001063 countsByYear W42000010632023 @default.
- W4200001063 crossrefType "journal-article" @default.
- W4200001063 hasAuthorship W4200001063A5024360840 @default.
- W4200001063 hasAuthorship W4200001063A5049280311 @default.
- W4200001063 hasBestOaLocation W42000010631 @default.
- W4200001063 hasConcept C105702510 @default.
- W4200001063 hasConcept C169760540 @default.
- W4200001063 hasConcept C172497186 @default.
- W4200001063 hasConcept C185263204 @default.
- W4200001063 hasConcept C2777348757 @default.
- W4200001063 hasConcept C2779083617 @default.
- W4200001063 hasConcept C2779246727 @default.
- W4200001063 hasConcept C2780723820 @default.
- W4200001063 hasConcept C86803240 @default.
- W4200001063 hasConcept C94487597 @default.
- W4200001063 hasConceptScore W4200001063C105702510 @default.
- W4200001063 hasConceptScore W4200001063C169760540 @default.
- W4200001063 hasConceptScore W4200001063C172497186 @default.
- W4200001063 hasConceptScore W4200001063C185263204 @default.
- W4200001063 hasConceptScore W4200001063C2777348757 @default.
- W4200001063 hasConceptScore W4200001063C2779083617 @default.
- W4200001063 hasConceptScore W4200001063C2779246727 @default.
- W4200001063 hasConceptScore W4200001063C2780723820 @default.