FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200015923> ?p ?o ?g. }

• W4200015923 endingPage "89" @default.
• W4200015923 startingPage "89" @default.
• W4200015923 abstract "Skin is a hierarchical and multi-cellular organ exposed to the external environment with a key protective and regulatory role. Wounds caused by disease and trauma can lead to a loss of function, which can be debilitating and even cause death. Accelerating the natural skin healing process and minimizing the risk of infection is a clinical challenge. Electrospinning is a key technology in the development of wound dressings and skin substitutes as it enables extracellular matrix-mimicking fibrous structures and delivery of bioactive materials. Honey is a promising biomaterial for use in skin tissue engineering applications and has antimicrobial properties and potential tissue regenerative properties. This preliminary study investigates a solution electrospun composite nanofibrous mesh based on polycaprolactone and a medical grade honey, SurgihoneyRO. The processing conditions were optimized and assessed by scanning electron microscopy to fabricate meshes with uniform fiber diameters and minimal presence of beads. The chemistry of the composite meshes was examined using Fourier transform infrared spectroscopy and X-ray photon spectroscopy showing incorporation of honey into the polymer matrix. Meshes incorporating honey had lower mechanical properties due to lower polymer content but were more hydrophilic, resulting in an increase in swelling and an accelerated degradation profile. The biocompatibility of the meshes was assessed using human dermal fibroblasts and adipose-derived stem cells, which showed comparable or higher cell metabolic activity and viability for SurgihoneyRO-containing meshes compared to polycaprolactone only meshes. The meshes showed no antibacterial properties in a disk diffusion test due to a lack of hydrogen peroxide production and release. The developed polycaprolactone-honey nanofibrous meshes have potential for use in skin applications." @default.
• W4200015923 created "2021-12-31" @default.
• W4200015923 creator A5004971904 @default.
• W4200015923 creator A5010577932 @default.
• W4200015923 creator A5011324823 @default.
• W4200015923 creator A5036297123 @default.
• W4200015923 creator A5060084029 @default.
• W4200015923 creator A5067434985 @default.
• W4200015923 date "2021-12-23" @default.
• W4200015923 modified "2023-10-18" @default.
• W4200015923 title "Preliminary Characterization of a Polycaprolactone-SurgihoneyRO Electrospun Mesh for Skin Tissue Engineering" @default.
• W4200015923 cites W1773947028 @default.
• W4200015923 cites W1897094843 @default.
• W4200015923 cites W1914616719 @default.
• W4200015923 cites W1949972382 @default.
• W4200015923 cites W1965501936 @default.
• W4200015923 cites W1970487243 @default.
• W4200015923 cites W1974603116 @default.
• W4200015923 cites W1990951242 @default.
• W4200015923 cites W1992740290 @default.
• W4200015923 cites W2000971499 @default.
• W4200015923 cites W2013746332 @default.
• W4200015923 cites W2025763370 @default.
• W4200015923 cites W2038551196 @default.
• W4200015923 cites W2045701919 @default.
• W4200015923 cites W2053471505 @default.
• W4200015923 cites W2062376074 @default.
• W4200015923 cites W2066225568 @default.
• W4200015923 cites W2074001489 @default.
• W4200015923 cites W2084495529 @default.
• W4200015923 cites W2086699454 @default.
• W4200015923 cites W2126109067 @default.
• W4200015923 cites W213050918 @default.
• W4200015923 cites W2137542731 @default.
• W4200015923 cites W2143816949 @default.
• W4200015923 cites W2187985754 @default.
• W4200015923 cites W2220643393 @default.
• W4200015923 cites W2288155788 @default.
• W4200015923 cites W2293652843 @default.
• W4200015923 cites W2301563261 @default.
• W4200015923 cites W2402202411 @default.
• W4200015923 cites W2511626655 @default.
• W4200015923 cites W2522390427 @default.
• W4200015923 cites W2523456976 @default.
• W4200015923 cites W2574904481 @default.
• W4200015923 cites W2579920203 @default.
• W4200015923 cites W2605720641 @default.
• W4200015923 cites W2614933640 @default.
• W4200015923 cites W2630111394 @default.
• W4200015923 cites W2742680589 @default.
• W4200015923 cites W2742907807 @default.
• W4200015923 cites W2748410302 @default.
• W4200015923 cites W2785784089 @default.
• W4200015923 cites W2800518462 @default.
• W4200015923 cites W2804120535 @default.
• W4200015923 cites W2885626252 @default.
• W4200015923 cites W2901561861 @default.
• W4200015923 cites W2908848894 @default.
• W4200015923 cites W2909564201 @default.
• W4200015923 cites W2910655557 @default.
• W4200015923 cites W2911261679 @default.
• W4200015923 cites W2932477481 @default.
• W4200015923 cites W2943128521 @default.
• W4200015923 cites W2944741063 @default.
• W4200015923 cites W2947094299 @default.
• W4200015923 cites W2952244481 @default.
• W4200015923 cites W2993724364 @default.
• W4200015923 cites W2995748319 @default.
• W4200015923 cites W3002295158 @default.
• W4200015923 cites W3011197841 @default.
• W4200015923 cites W3014663127 @default.
• W4200015923 cites W3015862870 @default.
• W4200015923 cites W3016723112 @default.
• W4200015923 cites W3048447146 @default.
• W4200015923 cites W3115493586 @default.
• W4200015923 cites W3119893738 @default.
• W4200015923 cites W3129175874 @default.
• W4200015923 cites W3141186455 @default.
• W4200015923 cites W3141775240 @default.
• W4200015923 cites W3153776300 @default.
• W4200015923 cites W3183063876 @default.
• W4200015923 cites W3194701635 @default.
• W4200015923 doi "https://doi.org/10.3390/ma15010089" @default.
• W4200015923 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35009233" @default.
• W4200015923 hasPublicationYear "2021" @default.
• W4200015923 type Work @default.
• W4200015923 citedByCount "1" @default.
• W4200015923 countsByYear W42000159232022 @default.
• W4200015923 crossrefType "journal-article" @default.
• W4200015923 hasAuthorship W4200015923A5004971904 @default.
• W4200015923 hasAuthorship W4200015923A5010577932 @default.
• W4200015923 hasAuthorship W4200015923A5011324823 @default.
• W4200015923 hasAuthorship W4200015923A5036297123 @default.
• W4200015923 hasAuthorship W4200015923A5060084029 @default.
• W4200015923 hasAuthorship W4200015923A5067434985 @default.
• W4200015923 hasBestOaLocation W42000159231 @default.
• W4200015923 hasConcept C104779481 @default.
• W4200015923 hasConcept C121684516 @default.

• next