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- W4200071888 abstract "To the Editor—We thank Drs Chang and Liaw for their interest in our article [1]. Our study was focused on socioeconomic, biologic, and clinical factors and their relationships with maternal to fetal transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–specific serum immunoglobulin G (IgG) and with development of a mucosal (breast milk) SARS-CoV-2–specific IgA response. The points raised by Chang and Liaw pertain to whether infection of infants was a result of maternal-fetal transmission of virus or via a fecal-oral route during natural childbirth. While we agree that the issues they raise are important for analysis of viral transmission, our study was not designed to measure this. Maternal IgG responses persist for several months after infection [2] and the 23-day half-life of IgG in the circulation ensures that maternal-derived fetal IgG (as measured in cord blood) is detectable long after infection has resolved. Whether the..." @default.
- W4200071888 created "2021-12-31" @default.
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- W4200071888 date "2021-12-20" @default.
- W4200071888 modified "2023-09-24" @default.
- W4200071888 title "Reply to Chang and Liaw" @default.
- W4200071888 doi "https://doi.org/10.1093/infdis/jiab618" @default.
- W4200071888 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34929040" @default.
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