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• W4200092306 abstract "Abstract Purpose To demonstrate, through numerical simulations, novel designs of spatially selective radiofrequency (RF) excitations of the fetal brain by both a restricted 2D slice and 3D inner‐volume selection. These designs exploit a single‐channel RF pulse, conventional gradient fields, and the spatially non‐linear Δ B 0 fields of a multi‐coil shim array, using an auto‐differentiation optimization algorithm. Methods The design algorithm jointly optimizes the RF pulse and the time‐varying Δ B 0 fields, which is produced by a 64‐channel multi‐coil Δ B 0 body array to augment the RF and the linear gradient fields, using an auto‐differentiation approach. Two design targets were specified, one a 4‐mm thick slice with a limited in‐slice extent in one dimension (“restricted slice”), and the other a 3D inner‐volume selection encompassing the fetal brain (“inner volume”). The RF duration was limited to 2 ms for the restricted slice excitation and 6 ms for the inner‐volume excitation. Results Excitation profiles were achieved for both the restricted slice excitation task (one‐minus‐minimum magnitude, 8%) within the region of interest (ROI) and (maximum‐minus‐zero magnitude, 8%) in the suppressed regions and the fetal brain volume excitation task (13% and 9%, respectively). Conclusions The proposed joint design of RF and time‐varying, spatially non‐linear Δ B 0 fields achieves the target excitation profiles with short RF pulse durations and demonstrates the potential to enhance fetal MRI with multi‐channel body shim arrays." @default.
• W4200092306 created "2021-12-31" @default.
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• W4200092306 date "2021-12-21" @default.
• W4200092306 modified "2023-10-01" @default.
• W4200092306 title "Selective RF excitation designs enabled by time‐varying spatially non‐linear Δ<i>B</i>₀ fields with applications in fetal MRI" @default.
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• W4200092306 doi "https://doi.org/10.1002/mrm.29114" @default.
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