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• W4200109050 endingPage "981" @default.
• W4200109050 startingPage "965" @default.
• W4200109050 abstract "Association mapping using crop cultivars allows identification of genetic loci of direct relevance to breeding. Here, 150 U.K. wheat (Triticum aestivum L.) cultivars genotyped with 23,288 single nucleotide polymorphisms (SNPs) were used for genome-wide association studies (GWAS) using historical phenotypic data for grain protein content, Hagberg falling number (HFN), test weight, and grain yield. Power calculations indicated experimental design would enable detection of quantitative trait loci (QTL) explaining ≥20% of the variation (PVE) at a relatively high power of >80%, falling to 40% for detection of a SNP with an R2 ≥ .5 with the same QTL. Genome-wide association studies identified marker-trait associations for all four traits. For HFN (h2 = .89), six QTL were identified, including a major locus on chromosome 7B explaining 49% PVE and reducing HFN by 44 s. For protein content (h2 = 0.86), 10 QTL were found on chromosomes 1A, 2A, 2B, 3A, 3B, and 6B, together explaining 48.9% PVE. For test weight, five QTL were identified (one on 1B and four on 3B; 26.3% PVE). Finally, 14 loci were identified for grain yield (h2 = 0.95) on eight chromosomes (1A, 2A, 2B, 2D, 3A, 5B, 6A, 6B; 68.1% PVE), of which five were located within 16 Mbp of genetic regions previously identified as under breeder selection in European wheat. Our study demonstrates the utility of exploiting historical crop datasets, identifying genomic targets for independent validation, and ultimately for wheat genetic improvement." @default.
• W4200109050 created "2021-12-31" @default.
• W4200109050 creator A5054375489 @default.
• W4200109050 creator A5063022035 @default.
• W4200109050 creator A5067607107 @default.
• W4200109050 creator A5071898738 @default.
• W4200109050 creator A5077954390 @default.
• W4200109050 date "2022-03-04" @default.
• W4200109050 modified "2023-10-13" @default.
• W4200109050 title "Genome‐wide association mapping of Hagberg falling number, protein content, test weight, and grain yield in U.K. wheat" @default.
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• W4200109050 doi "https://doi.org/10.1002/csc2.20692" @default.
• W4200109050 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35915786" @default.
• W4200109050 hasPublicationYear "2022" @default.

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