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- W4200109968 abstract "We report here about the development of a fiber optic biosensor for the detection of vitamin D. The sensing platform is based on a long period grating (LPG) inscribed into a specialty double cladding fiber, whose sensitivity is enhanced through the mode transition phenomenon by chemical etching of the fiber outer cladding. The LPG is further covered with a nanosized layer of graphene oxide, providing carboxylic functional groups for the covalent immobilization of a vitamin D specific antibody. The testing was conducted using the major circulating form of vitamin D3, i.e., 25-OH-D3 (molecular weight ~400 Da), for which concentrations within 10-1000 ng/mL in buffer solution were measured. A limit of detection of medical interest lower than 10 ng/mL was attained." @default.
- W4200109968 created "2021-12-31" @default.
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- W4200109968 date "2021-10-31" @default.
- W4200109968 modified "2023-10-16" @default.
- W4200109968 title "Fiber optic biosensor based on long period grating for the detection of vitamin D" @default.
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- W4200109968 doi "https://doi.org/10.1109/sensors47087.2021.9639624" @default.
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