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- W4200114547 abstract "Dry root rot (Rhizoctonia bataticola) is an important disease of lentils (Lens culinaris Medik.).To gain an insight into the molecular aspects of host-pathogen interactions, the RNA-seq approach was used in lentils following inoculation with R.bataticola. The RNA-Seq has generated >450 million high-quality reads (HQRs) and nearly 96.97% were properly aligned to the reference genome. Very high similarity in FPKM (fragments per kilobase of exon per million mapped fragments) values (R > 0.9) among biological replicates showed the consistency of the RNA-Seq results. The study revealed various DEGs (differentially expressed genes) that were associated with changes in phenolic compounds, transcription factors (TFs), antioxidants, receptor kinases, hormone signals which corresponded to the cell wall modification enzymes, defense-related metabolites, and jasmonic acid (JA)/ethylene (ET) pathways. Gene ontology (GO) categorization also showed similar kinds of significantly enriched similar GO terms. Interestingly, of the total unigenes (42,606), 12,648 got assembled and showed significant hit with Rhizoctonia species. String analysis also revealed the role of various disease responsive proteins viz., LRR family proteins, LRR-RLKs, protein kinases, etc. in the host-pathogen interaction. Insilico validation analysis was performed using Genevestigator® and DEGs belonging to six major defense-response groups viz., defense-related enzymes, disease responsive genes, hormones, kinases, PR (pathogenesis related) proteins, and TFs were validated. For the first time some key miRNA targets viz. miR156, miR159, miR167, miR169, and miR482 were identified from the studied transcriptome, which may have some vital role in Rhizoctonia-based responses in lentils. The study has revealed the molecular mechanisms of the lentil/R.bataticola interactions and also provided a theoretical approach for the development of lentil genotypes resistant to R.bataticola." @default.
- W4200114547 created "2021-12-31" @default.
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- W4200114547 date "2021-12-29" @default.
- W4200114547 modified "2023-10-16" @default.
- W4200114547 title "Insights into the Host-Pathogen Interaction Pathways through RNA-Seq Analysis of Lens culinaris Medik. in Response to Rhizoctonia bataticola Infection" @default.
- W4200114547 cites W1515629842 @default.
- W4200114547 cites W1543632701 @default.
- W4200114547 cites W1967535552 @default.
- W4200114547 cites W1968008181 @default.
- W4200114547 cites W1968912677 @default.
- W4200114547 cites W1969353942 @default.
- W4200114547 cites W1991307739 @default.
- W4200114547 cites W2001561276 @default.
- W4200114547 cites W2005889437 @default.
- W4200114547 cites W2007497503 @default.
- W4200114547 cites W2012774455 @default.
- W4200114547 cites W2024948763 @default.
- W4200114547 cites W2027240142 @default.
- W4200114547 cites W2029516086 @default.
- W4200114547 cites W2034819034 @default.
- W4200114547 cites W2036426468 @default.
- W4200114547 cites W2047667092 @default.
- W4200114547 cites W2050754685 @default.
- W4200114547 cites W2050942929 @default.
- W4200114547 cites W2051615088 @default.
- W4200114547 cites W2052001330 @default.
- W4200114547 cites W2059502315 @default.
- W4200114547 cites W2064066222 @default.
- W4200114547 cites W2065589216 @default.
- W4200114547 cites W2074596398 @default.
- W4200114547 cites W2077200333 @default.
- W4200114547 cites W2090658825 @default.
- W4200114547 cites W2096173332 @default.
- W4200114547 cites W2096451658 @default.
- W4200114547 cites W2098965315 @default.
- W4200114547 cites W2106596862 @default.
- W4200114547 cites W2107496520 @default.
- W4200114547 cites W2112907855 @default.
- W4200114547 cites W2114104545 @default.
- W4200114547 cites W2126419817 @default.
- W4200114547 cites W2132059918 @default.
- W4200114547 cites W2143613475 @default.
- W4200114547 cites W2147321004 @default.
- W4200114547 cites W2147799946 @default.
- W4200114547 cites W2150116770 @default.
- W4200114547 cites W2154645267 @default.
- W4200114547 cites W2155737125 @default.
- W4200114547 cites W2159482845 @default.
- W4200114547 cites W2159675211 @default.
- W4200114547 cites W2160910949 @default.
- W4200114547 cites W2164154943 @default.
- W4200114547 cites W2166318579 @default.
- W4200114547 cites W2171192872 @default.
- W4200114547 cites W2178183339 @default.
- W4200114547 cites W2471462018 @default.
- W4200114547 cites W2560844000 @default.
- W4200114547 cites W2577490495 @default.
- W4200114547 cites W2580710364 @default.
- W4200114547 cites W2610763352 @default.
- W4200114547 cites W2788318073 @default.
- W4200114547 cites W2799336468 @default.
- W4200114547 cites W2800206218 @default.
- W4200114547 cites W2888223117 @default.
- W4200114547 cites W2900759676 @default.
- W4200114547 cites W2919115771 @default.
- W4200114547 cites W2923899675 @default.
- W4200114547 cites W2946123493 @default.
- W4200114547 cites W2948794891 @default.
- W4200114547 cites W2985884608 @default.
- W4200114547 cites W2992367661 @default.
- W4200114547 cites W3000721983 @default.
- W4200114547 cites W3014184260 @default.
- W4200114547 cites W3021097494 @default.
- W4200114547 cites W3037248378 @default.
- W4200114547 cites W3047607456 @default.
- W4200114547 cites W3119642100 @default.
- W4200114547 cites W3124452739 @default.
- W4200114547 cites W3156869840 @default.
- W4200114547 cites W3187176150 @default.
- W4200114547 cites W3205361976 @default.
- W4200114547 cites W4294216483 @default.
- W4200114547 cites W4366445871 @default.
- W4200114547 doi "https://doi.org/10.3390/genes13010090" @default.