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- W4200165491 abstract "β-Hydroxybutyl acid (βOHB), the most prevalent type of ketone in the human body, is involved in the pathogenesis of cognitive disorders, especially Alzheimer's dementia (AD), through a variety of mechanisms, such as enhancing mitochondrial metabolism, regulating signaling molecule, increasing histone acetylation, affecting the metabolism of Aβ and Tau proteins, inhibiting inflammation and lipid metabolism, and regulating intestinal microbes. Based on the above findings, clinical drug development in AD has begun to focus on βOHB." @default.
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- W4200165491 date "2022-02-01" @default.
- W4200165491 modified "2023-10-12" @default.
- W4200165491 title "The potential pharmacological mechanisms of β-hydroxybutyrate for improving cognitive functions" @default.
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- W4200165491 doi "https://doi.org/10.1016/j.coph.2021.10.005" @default.
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