Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200175892> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W4200175892 abstract "Acute generalized exanthematous pustulosis is a severe, usually drug-related reaction, characterized by an acute onset of mainly small non-follicular pustules on an erythematous base. Most cases of acute generalized exanthematous pustulosis (AGEP) clear quickly with a systemic corticosteroid, but severe or recalcitrant cases may need other systemic therapies. In this case, a man in his 40 s with a history of psoriasis consulted a physician about widespread erythema, pustules, target lesions, and fever after the administration of a quadruple antituberculosis drug. Routine laboratory testing revealed elevated white blood cell count and C-reactive protein. The histopathology showed subcorneal pustules, spongiosis as well as lymphocyte and eosinophils infiltration in the dermis. The patient was diagnosed with definitive AGEP according to the diagnostic score from the EuroSCAR study. Cutaneous lesions especially pustules and erythema multiforme-like lesions on the upper arms and palms are crucial for distinguishing AGEP from Generalized pustular psoriasis. The patient was treated with secukinumab as a result of his failure to respond to topical corticosteroids and constrain of systemic steroids. Remission with secukinumab therapy was safe without increased risks of infections. This case indicates that secukinumab is a potential therapy that can rapidly improve the clinical symptoms of AGEP." @default.
- W4200175892 created "2021-12-31" @default.
- W4200175892 creator A5014258731 @default.
- W4200175892 creator A5017947172 @default.
- W4200175892 creator A5018732161 @default.
- W4200175892 creator A5026061299 @default.
- W4200175892 creator A5029571869 @default.
- W4200175892 creator A5038253545 @default.
- W4200175892 creator A5067882671 @default.
- W4200175892 creator A5076597358 @default.
- W4200175892 creator A5083424520 @default.
- W4200175892 creator A5085555760 @default.
- W4200175892 date "2021-12-16" @default.
- W4200175892 modified "2023-09-28" @default.
- W4200175892 title "Case Report: Successful Treatment of Acute Generalized Exanthematous Pustulosis With Secukinumab" @default.
- W4200175892 cites W1605299698 @default.
- W4200175892 cites W2021384711 @default.
- W4200175892 cites W2048073038 @default.
- W4200175892 cites W2091918038 @default.
- W4200175892 cites W2115293219 @default.
- W4200175892 cites W3085427351 @default.
- W4200175892 cites W3102962023 @default.
- W4200175892 doi "https://doi.org/10.3389/fmed.2021.758354" @default.
- W4200175892 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34993208" @default.
- W4200175892 hasPublicationYear "2021" @default.
- W4200175892 type Work @default.
- W4200175892 citedByCount "3" @default.
- W4200175892 countsByYear W42001758922022 @default.
- W4200175892 countsByYear W42001758922023 @default.
- W4200175892 crossrefType "journal-article" @default.
- W4200175892 hasAuthorship W4200175892A5014258731 @default.
- W4200175892 hasAuthorship W4200175892A5017947172 @default.
- W4200175892 hasAuthorship W4200175892A5018732161 @default.
- W4200175892 hasAuthorship W4200175892A5026061299 @default.
- W4200175892 hasAuthorship W4200175892A5029571869 @default.
- W4200175892 hasAuthorship W4200175892A5038253545 @default.
- W4200175892 hasAuthorship W4200175892A5067882671 @default.
- W4200175892 hasAuthorship W4200175892A5076597358 @default.
- W4200175892 hasAuthorship W4200175892A5083424520 @default.
- W4200175892 hasAuthorship W4200175892A5085555760 @default.
- W4200175892 hasBestOaLocation W42001758921 @default.
- W4200175892 hasConcept C16005928 @default.
- W4200175892 hasConcept C203014093 @default.
- W4200175892 hasConcept C2776260265 @default.
- W4200175892 hasConcept C2776907424 @default.
- W4200175892 hasConcept C2777077863 @default.
- W4200175892 hasConcept C2779121184 @default.
- W4200175892 hasConcept C2779234776 @default.
- W4200175892 hasConcept C2779244835 @default.
- W4200175892 hasConcept C2779786854 @default.
- W4200175892 hasConcept C2780425889 @default.
- W4200175892 hasConcept C2780564577 @default.
- W4200175892 hasConcept C2780664588 @default.
- W4200175892 hasConcept C2781320243 @default.
- W4200175892 hasConcept C71924100 @default.
- W4200175892 hasConceptScore W4200175892C16005928 @default.
- W4200175892 hasConceptScore W4200175892C203014093 @default.
- W4200175892 hasConceptScore W4200175892C2776260265 @default.
- W4200175892 hasConceptScore W4200175892C2776907424 @default.
- W4200175892 hasConceptScore W4200175892C2777077863 @default.
- W4200175892 hasConceptScore W4200175892C2779121184 @default.
- W4200175892 hasConceptScore W4200175892C2779234776 @default.
- W4200175892 hasConceptScore W4200175892C2779244835 @default.
- W4200175892 hasConceptScore W4200175892C2779786854 @default.
- W4200175892 hasConceptScore W4200175892C2780425889 @default.
- W4200175892 hasConceptScore W4200175892C2780564577 @default.
- W4200175892 hasConceptScore W4200175892C2780664588 @default.
- W4200175892 hasConceptScore W4200175892C2781320243 @default.
- W4200175892 hasConceptScore W4200175892C71924100 @default.
- W4200175892 hasLocation W42001758921 @default.
- W4200175892 hasLocation W42001758922 @default.
- W4200175892 hasLocation W42001758923 @default.
- W4200175892 hasLocation W42001758924 @default.
- W4200175892 hasOpenAccess W4200175892 @default.
- W4200175892 hasPrimaryLocation W42001758921 @default.
- W4200175892 hasRelatedWork W1965091379 @default.
- W4200175892 hasRelatedWork W1986597285 @default.
- W4200175892 hasRelatedWork W2036871717 @default.
- W4200175892 hasRelatedWork W2289529284 @default.
- W4200175892 hasRelatedWork W2386568283 @default.
- W4200175892 hasRelatedWork W2548334338 @default.
- W4200175892 hasRelatedWork W2795298057 @default.
- W4200175892 hasRelatedWork W2980716025 @default.
- W4200175892 hasRelatedWork W3128780318 @default.
- W4200175892 hasRelatedWork W4200175892 @default.
- W4200175892 hasVolume "8" @default.
- W4200175892 isParatext "false" @default.
- W4200175892 isRetracted "false" @default.
- W4200175892 workType "article" @default.