FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200199049> ?p ?o ?g. }

• W4200199049 endingPage "100176" @default.
• W4200199049 startingPage "100176" @default.
• W4200199049 abstract "Phytochemistry of Centella asiatica (CA) gained momentum after the discovery of asiaticoside in the early 1940s. Though there is lot of literature on this precious herb, its chemistry has not been comprehensively reviewed. Moreover, several duplicate names, synonyms and contradictory findings were observed in CA literature. The traditional, food and vegetable, pharmaceutical and cosmetic uses of CA are steadily on the rise, resulting in its ever increasing biomass requirements. This article is an inclusive review of the last eight decades of chemistry of CA. Its biological activities, food and beverage, cosmetic applications and natural and alternate biomass sources are also assessed. CA literature for this review was gathered from web-based resources such as PubMed, Scopus and Google Scholar, and chemical structures were drawn using ChemDraw software. So far 139 secondary metabolites were isolated from CA, viz., ursane-type triterpenes (11), oleanane-type triterpenes (5), ursane-type triterpene glycosides (30), oleanane-type triterpene glycosides (14), dammarane-type triterpene glycosides (15), steroids (4), steroid glycosides (2), flavonoids (18), polyacetylenes (9), phenolic acids (13) and other miscellaneous compounds (18). Of these 139 compounds, 70 are new entities described for the first time. Most prominent CA metabolites are the four ursane type triterpenes, viz., asiatic acid, madecassic acid, asiaticoside and madecassoside. Naming issues and contradictory findings are resolved in this article. Biological activities of CA and its secondary metabolites are also reviewed. The wide use of CA as a vegetable and food ingredient is justified by the antioxidant activities of its phenolics, flavonoids and other constituents. The traditional uses, geographical sources, conservation status, industrial demand, elite clones, alternative sources, chemical variability, ecological and other allied parameters and quality control requirements of CA are also discussed in the context of its chemistry and secondary metabolites. This review emphasizes the need to study the biology of the least investigated CA metabolites, viz., oleanane-type triterpenoids, caffeoyl quinic acids, polyacetylenes, phenolics, miscellaneous compounds. Moreover, a comprehensive description of the secondary metabolites in CA will aid its future chemistry, biosynthesis, chemical transformation and biological activity studies." @default.
• W4200199049 created "2021-12-31" @default.
• W4200199049 creator A5015578188 @default.
• W4200199049 creator A5057824187 @default.
• W4200199049 creator A5067197168 @default.
• W4200199049 date "2022-02-01" @default.
• W4200199049 modified "2023-10-01" @default.
• W4200199049 title "Centella asiatica: Secondary metabolites, biological activities and biomass sources" @default.
• W4200199049 cites W141595154 @default.
• W4200199049 cites W1559579620 @default.
• W4200199049 cites W1593144664 @default.
• W4200199049 cites W1800896977 @default.
• W4200199049 cites W1952455177 @default.
• W4200199049 cites W1963590320 @default.
• W4200199049 cites W1964236848 @default.
• W4200199049 cites W1964694445 @default.
• W4200199049 cites W1965199203 @default.
• W4200199049 cites W1967537536 @default.
• W4200199049 cites W1968141753 @default.
• W4200199049 cites W1968705390 @default.
• W4200199049 cites W1970310642 @default.
• W4200199049 cites W1970472997 @default.
• W4200199049 cites W1974376656 @default.
• W4200199049 cites W1976505302 @default.
• W4200199049 cites W1977646857 @default.
• W4200199049 cites W1978939330 @default.
• W4200199049 cites W1981721889 @default.
• W4200199049 cites W1981874160 @default.
• W4200199049 cites W1985597690 @default.
• W4200199049 cites W1989354404 @default.
• W4200199049 cites W1994296310 @default.
• W4200199049 cites W1994453373 @default.
• W4200199049 cites W1994792408 @default.
• W4200199049 cites W1996036468 @default.
• W4200199049 cites W1998901934 @default.
• W4200199049 cites W2004431551 @default.
• W4200199049 cites W2009591797 @default.
• W4200199049 cites W2014301035 @default.
• W4200199049 cites W2019666039 @default.
• W4200199049 cites W2021784041 @default.
• W4200199049 cites W2031561250 @default.
• W4200199049 cites W2032630856 @default.
• W4200199049 cites W2033129896 @default.
• W4200199049 cites W2033327918 @default.
• W4200199049 cites W2037248352 @default.
• W4200199049 cites W2039820123 @default.
• W4200199049 cites W2045803793 @default.
• W4200199049 cites W2046847011 @default.
• W4200199049 cites W2046876555 @default.
• W4200199049 cites W2049587028 @default.
• W4200199049 cites W2050652120 @default.
• W4200199049 cites W2051827697 @default.
• W4200199049 cites W2053837068 @default.
• W4200199049 cites W2058208502 @default.
• W4200199049 cites W2060465907 @default.
• W4200199049 cites W2061895855 @default.
• W4200199049 cites W2063760395 @default.
• W4200199049 cites W2066281601 @default.
• W4200199049 cites W2066886841 @default.
• W4200199049 cites W2067242082 @default.
• W4200199049 cites W2067362040 @default.
• W4200199049 cites W2070854535 @default.
• W4200199049 cites W2071066258 @default.
• W4200199049 cites W2073312265 @default.
• W4200199049 cites W2074570728 @default.
• W4200199049 cites W2075598806 @default.
• W4200199049 cites W2081168487 @default.
• W4200199049 cites W2081206066 @default.
• W4200199049 cites W2082301603 @default.
• W4200199049 cites W2086744270 @default.
• W4200199049 cites W2086959952 @default.
• W4200199049 cites W2088349262 @default.
• W4200199049 cites W2089114299 @default.
• W4200199049 cites W2089539033 @default.
• W4200199049 cites W2098708517 @default.
• W4200199049 cites W2099556643 @default.
• W4200199049 cites W2106828037 @default.
• W4200199049 cites W2110694864 @default.
• W4200199049 cites W2118555435 @default.
• W4200199049 cites W2120050118 @default.
• W4200199049 cites W2124211842 @default.
• W4200199049 cites W2125933976 @default.
• W4200199049 cites W2126054228 @default.
• W4200199049 cites W2127013358 @default.
• W4200199049 cites W2129942927 @default.
• W4200199049 cites W2134523237 @default.
• W4200199049 cites W2138998035 @default.
• W4200199049 cites W2141070063 @default.
• W4200199049 cites W2143088276 @default.
• W4200199049 cites W2145883044 @default.
• W4200199049 cites W2163811480 @default.
• W4200199049 cites W2164090829 @default.
• W4200199049 cites W2166658797 @default.
• W4200199049 cites W2168556140 @default.
• W4200199049 cites W2237719304 @default.
• W4200199049 cites W2339528123 @default.
• W4200199049 cites W2412913996 @default.
• W4200199049 cites W2415722237 @default.

• next