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- W4200202014 abstract "Eurothiocins C-H (1-6), six unusual thioester-containing benzoate derivatives, were isolated from the deep-sea-derived fungus Talaromyces indigoticus FS688 together with a known analogue eurothiocin A (7). Their structures were elucidated through spectroscopic analysis and the absolute configurations were determined by X-ray diffraction and ECD calculations. In addition, compound 1 exhibited significant inhibitory activity against α-glucosidase with an IC50 value of 5.4 μM, while compounds 4 and 5 showed moderate effects with IC50 values of 33.6 and 72.1 μM, respectively. A preliminary structure-activity relationship is discussed and a docking analysis was performed." @default.
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- W4200202014 date "2021-12-29" @default.
- W4200202014 modified "2023-10-06" @default.
- W4200202014 title "Thioester-Containing Benzoate Derivatives with α-Glucosidase Inhibitory Activity from the Deep-Sea-Derived Fungus Talaromyces indigoticus FS688" @default.
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- W4200202014 doi "https://doi.org/10.3390/md20010033" @default.
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