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- W4200207294 abstract "The downregulation of reactive oxygen species (ROS) facilitates precancerous tumor development, even though increasing the level of ROS can promote metastasis. The transforming growth factor-beta (TGF-β) signaling pathway plays an anti-tumorigenic role in the initial stages of cancer development but a pro-tumorigenic role in later stages that fosters cancer metastasis. TGF-β can regulate the production of ROS unambiguously or downregulate antioxidant systems. ROS can influence TGF-β signaling by enhancing its expression and activation. Thus, TGF-β signaling and ROS might significantly coordinate cellular processes that cancer cells employ to expedite their malignancy. In cancer cells, interplay between oxidative stress and TGF-β is critical for tumorigenesis and cancer progression. Thus, both TGF-β and ROS can develop a robust relationship in cancer cells to augment their malignancy. This review focuses on the appropriate interpretation of this crosstalk between TGF-β and oxidative stress in cancer, exposing new potential approaches in cancer biology." @default.
- W4200207294 created "2021-12-31" @default.
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- W4200207294 date "2021-12-07" @default.
- W4200207294 modified "2023-10-16" @default.
- W4200207294 title "Correlation between Oxidative Stress and Transforming Growth Factor-Beta in Cancers" @default.
- W4200207294 cites W133186721 @default.
- W4200207294 cites W1575754639 @default.
- W4200207294 cites W1599970242 @default.
- W4200207294 cites W1965546606 @default.
- W4200207294 cites W1967173409 @default.
- W4200207294 cites W1980780168 @default.
- W4200207294 cites W1984205437 @default.
- W4200207294 cites W1984434134 @default.
- W4200207294 cites W1985130041 @default.
- W4200207294 cites W1985374023 @default.
- W4200207294 cites W1989987141 @default.
- W4200207294 cites W1994738588 @default.
- W4200207294 cites W1996211554 @default.
- W4200207294 cites W1996311090 @default.
- W4200207294 cites W1998869909 @default.
- W4200207294 cites W1999132074 @default.
- W4200207294 cites W2005627263 @default.
- W4200207294 cites W2014475655 @default.
- W4200207294 cites W2018457531 @default.
- W4200207294 cites W2020348993 @default.
- W4200207294 cites W2021675524 @default.
- W4200207294 cites W2022352851 @default.
- W4200207294 cites W2023144855 @default.
- W4200207294 cites W2027860197 @default.
- W4200207294 cites W2028897202 @default.
- W4200207294 cites W2031718974 @default.
- W4200207294 cites W2033147946 @default.
- W4200207294 cites W2036659255 @default.
- W4200207294 cites W2040074251 @default.
- W4200207294 cites W2041154504 @default.
- W4200207294 cites W2042637324 @default.
- W4200207294 cites W2046751492 @default.
- W4200207294 cites W2056307667 @default.
- W4200207294 cites W2059174198 @default.
- W4200207294 cites W2060315334 @default.
- W4200207294 cites W2060638322 @default.
- W4200207294 cites W2061234580 @default.
- W4200207294 cites W2062845561 @default.
- W4200207294 cites W2064662817 @default.
- W4200207294 cites W2068982039 @default.
- W4200207294 cites W2069524101 @default.
- W4200207294 cites W2070011813 @default.
- W4200207294 cites W2070280275 @default.
- W4200207294 cites W2073575123 @default.
- W4200207294 cites W2076496958 @default.
- W4200207294 cites W2076583198 @default.
- W4200207294 cites W2077168519 @default.
- W4200207294 cites W2082619639 @default.
- W4200207294 cites W2084414513 @default.
- W4200207294 cites W2085128107 @default.
- W4200207294 cites W2085719701 @default.
- W4200207294 cites W2086378628 @default.
- W4200207294 cites W2086692663 @default.
- W4200207294 cites W2087467372 @default.
- W4200207294 cites W2087727029 @default.
- W4200207294 cites W2089805984 @default.
- W4200207294 cites W2089959661 @default.
- W4200207294 cites W2090676036 @default.
- W4200207294 cites W2090741482 @default.
- W4200207294 cites W2090900051 @default.
- W4200207294 cites W2094280155 @default.
- W4200207294 cites W2100259806 @default.
- W4200207294 cites W2101466169 @default.
- W4200207294 cites W2104105936 @default.
- W4200207294 cites W2110167662 @default.
- W4200207294 cites W2110966376 @default.
- W4200207294 cites W2111916686 @default.
- W4200207294 cites W2115530800 @default.
- W4200207294 cites W2118655588 @default.
- W4200207294 cites W2124413979 @default.
- W4200207294 cites W2128077493 @default.
- W4200207294 cites W2132008353 @default.
- W4200207294 cites W2133598334 @default.
- W4200207294 cites W2136280424 @default.
- W4200207294 cites W2138412447 @default.
- W4200207294 cites W2140525205 @default.
- W4200207294 cites W2141603634 @default.
- W4200207294 cites W2141860100 @default.
- W4200207294 cites W2146738245 @default.
- W4200207294 cites W2148937254 @default.
- W4200207294 cites W2154589460 @default.
- W4200207294 cites W2156277739 @default.
- W4200207294 cites W2161186807 @default.