Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200207730> ?p ?o ?g. }
Showing items 1 to 61 of
61
with 100 items per page.
- W4200207730 abstract "Background: Transjugular intrahepatic portosystemic shunt (TIPS) is an established intervention for symptomatic portal hypertension. Following TIPS creation, 22-50% of patients experience hepatic encephalopathy (HE), with symptoms ranging from mild confusion to coma. While HE can be medically managed, refractory cases may require downsizing of the TIPS which can be accomplished by deploying a smaller caliber stent within the original shunt. Decreasing shunt diameter redirects blood flow back through liver parenchyma. The purpose of this study was to evaluate the efficacy of TIPS downsizing for the treatment of medically refractory post-TIPS HE.
 Methods: An IRB-approved, HIPAA compliant retrospective review was performed. A search of an institutional radiology database yielded 45 patients who underwent TIPS downsizing between 2011-2021. Four patients were excluded due to lack of post-TIPS HE, and a total 41 patients were included in the study. Clinical and serologic data were obtained for all 41 patients. The primary objective was to determine the efficacy of TIPS downsizing for reduction of HE as measured by the West Haven criteria. Secondary endpoints included post-downsize recurrence of ascites or gastrointestinal bleeding, procedural complications, and thirty-day mortality.
 Results: TIPS downsizing was performed in all 41 patients with a 9.8% thirty-day mortality rate. No deaths were attributable to the procedure itself. Of the remaining patients, twenty-seven patients (65.9%) had improvement in HE and 10 patients (24.4%) proceeded to TIPS occlusion due to refractory HE. The average pre-downsize and post-downsize West Haven grades were 2.9 ± 0.5 and 1.9 ± 1.2, respectively. One patient (2.4%) had spontaneous TIPS thrombosis after downsizing and developed gastrointestinal bleeding requiring embolization; 15 patients (36.6%) experienced recurrent ascites.
 Conclusion: In this population, TIPS downsizing improved medically refractory HE in 65.9% of patients with a 2.4% risk of recurrent gastrointestinal bleeding, 36.6% risk of recurrent ascites, and 9.8% thirty-day mortality." @default.
- W4200207730 created "2021-12-31" @default.
- W4200207730 creator A5038347812 @default.
- W4200207730 creator A5079895951 @default.
- W4200207730 creator A5087353724 @default.
- W4200207730 date "2021-12-10" @default.
- W4200207730 modified "2023-09-23" @default.
- W4200207730 title "Transjugular Intrahepatic Portosystemic Shunt Reduction for Medically Refractory Hepatic Encephalopathy" @default.
- W4200207730 doi "https://doi.org/10.18060/25741" @default.
- W4200207730 hasPublicationYear "2021" @default.
- W4200207730 type Work @default.
- W4200207730 citedByCount "0" @default.
- W4200207730 crossrefType "journal-article" @default.
- W4200207730 hasAuthorship W4200207730A5038347812 @default.
- W4200207730 hasAuthorship W4200207730A5079895951 @default.
- W4200207730 hasAuthorship W4200207730A5087353724 @default.
- W4200207730 hasBestOaLocation W42002077301 @default.
- W4200207730 hasConcept C121332964 @default.
- W4200207730 hasConcept C126322002 @default.
- W4200207730 hasConcept C126838900 @default.
- W4200207730 hasConcept C141071460 @default.
- W4200207730 hasConcept C142424586 @default.
- W4200207730 hasConcept C2776988256 @default.
- W4200207730 hasConcept C2777214474 @default.
- W4200207730 hasConcept C2778808290 @default.
- W4200207730 hasConcept C2780325230 @default.
- W4200207730 hasConcept C2780496750 @default.
- W4200207730 hasConcept C2781033279 @default.
- W4200207730 hasConcept C71924100 @default.
- W4200207730 hasConcept C87355193 @default.
- W4200207730 hasConceptScore W4200207730C121332964 @default.
- W4200207730 hasConceptScore W4200207730C126322002 @default.
- W4200207730 hasConceptScore W4200207730C126838900 @default.
- W4200207730 hasConceptScore W4200207730C141071460 @default.
- W4200207730 hasConceptScore W4200207730C142424586 @default.
- W4200207730 hasConceptScore W4200207730C2776988256 @default.
- W4200207730 hasConceptScore W4200207730C2777214474 @default.
- W4200207730 hasConceptScore W4200207730C2778808290 @default.
- W4200207730 hasConceptScore W4200207730C2780325230 @default.
- W4200207730 hasConceptScore W4200207730C2780496750 @default.
- W4200207730 hasConceptScore W4200207730C2781033279 @default.
- W4200207730 hasConceptScore W4200207730C71924100 @default.
- W4200207730 hasConceptScore W4200207730C87355193 @default.
- W4200207730 hasIssue "1" @default.
- W4200207730 hasLocation W42002077301 @default.
- W4200207730 hasOpenAccess W4200207730 @default.
- W4200207730 hasPrimaryLocation W42002077301 @default.
- W4200207730 hasRelatedWork W157618018 @default.
- W4200207730 hasRelatedWork W2029697393 @default.
- W4200207730 hasRelatedWork W2336270053 @default.
- W4200207730 hasRelatedWork W2392081489 @default.
- W4200207730 hasRelatedWork W2479927420 @default.
- W4200207730 hasRelatedWork W2485856008 @default.
- W4200207730 hasRelatedWork W2504122359 @default.
- W4200207730 hasRelatedWork W3197710337 @default.
- W4200207730 hasRelatedWork W3202461180 @default.
- W4200207730 hasRelatedWork W4321368282 @default.
- W4200207730 hasVolume "4" @default.
- W4200207730 isParatext "false" @default.
- W4200207730 isRetracted "false" @default.
- W4200207730 workType "article" @default.