FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200207776> ?p ?o ?g. }

• W4200207776 abstract "The gut microbiome has been linked to breast cancer via immune, inflammatory, and hormonal mechanisms. We examined the relation between adolescent breast density and gut microbial composition and function in a cohort of Chilean girls. This cross-sectional study included 218 female participants in the Growth and Obesity Cohort Study who were 2 years post-menarche. We measured absolute breast fibroglandular volume (aFGV) and derived percent FGV (%FGV) using dual energy X-ray absorptiometry. All participants provided a fecal sample. The gut microbiome was characterized using 16S ribosomal RNA sequencing of the V3-V4 hypervariable region. We examined alpha diversity and beta diversity across terciles of %FGV and aFGV. We used MaAsLin2 for multivariable general linear modeling to assess differential taxa and predicted metabolic pathway abundance (MetaCyc) between %FGV and aFGV terciles. All models were adjusted for potential confounding variables and corrected for multiple comparisons. The mean %FGV and aFGV was 49.5% and 217.0 cm3, respectively, among study participants. Similar median alpha diversity levels were found across %FGV and aFGV terciles when measured by the Shannon diversity index (%FGV T1: 4.0, T2: 3.9, T3: 4.1; aFGV T1: 4.0, T2: 4.0, T3: 4.1). %FGV was associated with differences in beta diversity (R2 = 0.012, p=0.02). No genera were differentially abundant when comparing %FGV nor aFGV terciles after adjusting for potential confounders (q > 0.56 for all genera). We found no associations between predicted MetaCyc pathway abundance and %FGV and aFGV. Overall, breast density measured at 2 years post-menarche was not associated with composition and predicted function of the gut microbiome among adolescent Chilean girls." @default.
• W4200207776 created "2021-12-31" @default.
• W4200207776 creator A5004309176 @default.
• W4200207776 creator A5013286348 @default.
• W4200207776 creator A5026514859 @default.
• W4200207776 creator A5033603757 @default.
• W4200207776 creator A5043468657 @default.
• W4200207776 creator A5054676390 @default.
• W4200207776 creator A5076837123 @default.
• W4200207776 date "2021-12-17" @default.
• W4200207776 modified "2023-09-26" @default.
• W4200207776 title "The Association Between Breast Density and Gut Microbiota Composition at 2 Years Post-Menarche: A Cross-Sectional Study of Adolescents in Santiago, Chile" @default.
• W4200207776 cites W1574620960 @default.
• W4200207776 cites W1829841328 @default.
• W4200207776 cites W1970668319 @default.
• W4200207776 cites W1995865969 @default.
• W4200207776 cites W1995875735 @default.
• W4200207776 cites W1999245280 @default.
• W4200207776 cites W2032037035 @default.
• W4200207776 cites W2034285706 @default.
• W4200207776 cites W2041457600 @default.
• W4200207776 cites W2043812249 @default.
• W4200207776 cites W2046194218 @default.
• W4200207776 cites W2056036448 @default.
• W4200207776 cites W2056279562 @default.
• W4200207776 cites W2073332363 @default.
• W4200207776 cites W2077553363 @default.
• W4200207776 cites W2078978161 @default.
• W4200207776 cites W2090058679 @default.
• W4200207776 cites W2110065044 @default.
• W4200207776 cites W2115098571 @default.
• W4200207776 cites W2116846792 @default.
• W4200207776 cites W2123438666 @default.
• W4200207776 cites W2134111015 @default.
• W4200207776 cites W2145664556 @default.
• W4200207776 cites W2149421543 @default.
• W4200207776 cites W2161949501 @default.
• W4200207776 cites W2162279588 @default.
• W4200207776 cites W2163060364 @default.
• W4200207776 cites W2164536401 @default.
• W4200207776 cites W2165112637 @default.
• W4200207776 cites W2166060130 @default.
• W4200207776 cites W2167062509 @default.
• W4200207776 cites W2171437158 @default.
• W4200207776 cites W2401404581 @default.
• W4200207776 cites W2462303459 @default.
• W4200207776 cites W2532087401 @default.
• W4200207776 cites W2574425289 @default.
• W4200207776 cites W2592367925 @default.
• W4200207776 cites W2640475594 @default.
• W4200207776 cites W2786335128 @default.
• W4200207776 cites W2885273732 @default.
• W4200207776 cites W2898942477 @default.
• W4200207776 cites W2937419365 @default.
• W4200207776 cites W2944217428 @default.
• W4200207776 cites W2963276645 @default.
• W4200207776 cites W2970913246 @default.
• W4200207776 cites W3003869653 @default.
• W4200207776 cites W3019168548 @default.
• W4200207776 cites W3031163505 @default.
• W4200207776 cites W3082901035 @default.
• W4200207776 cites W3105231146 @default.
• W4200207776 cites W3106817752 @default.
• W4200207776 cites W3113000218 @default.
• W4200207776 cites W3121497940 @default.
• W4200207776 cites W3138215020 @default.
• W4200207776 cites W3146884365 @default.
• W4200207776 cites W3202462308 @default.
• W4200207776 cites W3211779138 @default.
• W4200207776 cites W4206296122 @default.
• W4200207776 cites W4235237096 @default.
• W4200207776 cites W906064262 @default.
• W4200207776 doi "https://doi.org/10.3389/fcimb.2021.794610" @default.
• W4200207776 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34976871" @default.
• W4200207776 hasPublicationYear "2021" @default.
• W4200207776 type Work @default.
• W4200207776 citedByCount "3" @default.
• W4200207776 countsByYear W42002077762022 @default.
• W4200207776 countsByYear W42002077762023 @default.
• W4200207776 crossrefType "journal-article" @default.
• W4200207776 hasAuthorship W4200207776A5004309176 @default.
• W4200207776 hasAuthorship W4200207776A5013286348 @default.
• W4200207776 hasAuthorship W4200207776A5026514859 @default.
• W4200207776 hasAuthorship W4200207776A5033603757 @default.
• W4200207776 hasAuthorship W4200207776A5043468657 @default.
• W4200207776 hasAuthorship W4200207776A5054676390 @default.
• W4200207776 hasAuthorship W4200207776A5076837123 @default.
• W4200207776 hasBestOaLocation W42002077761 @default.
• W4200207776 hasConcept C126322002 @default.
• W4200207776 hasConcept C143121216 @default.
• W4200207776 hasConcept C144024400 @default.
• W4200207776 hasConcept C149923435 @default.
• W4200207776 hasConcept C18903297 @default.
• W4200207776 hasConcept C23913935 @default.
• W4200207776 hasConcept C25147867 @default.
• W4200207776 hasConcept C42407357 @default.
• W4200207776 hasConcept C53565203 @default.
• W4200207776 hasConcept C60644358 @default.
• W4200207776 hasConcept C71924100 @default.
• W4200207776 hasConcept C72563966 @default.

• next