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- W4200207813 abstract "Autism spectrum disorder (ASD) and schizophrenia (SCZ) are separate disorders, with distinct clinical profiles and natural histories. ASD, typically diagnosed in childhood, is characterized by restricted or repetitive interests or behaviors and impaired social communication, and it tends to have a stable course. SCZ, typically diagnosed in adolescence or adulthood, is characterized by hallucinations and delusions, and tends to be associated with declining function. However, youth with ASD are three to six times more likely to develop SCZ than their neurotypical counterparts, and increasingly, research has shown that ASD and SCZ converge at several levels. We conducted a systematic review of studies since 2013 relevant to understanding this convergence, and present here a narrative synthesis of key findings, which we have organized into four broad categories: symptoms and behavior, perception and cognition, biomarkers, and genetic and environmental risk. We then discuss opportunities for future research into the phenomenology and neurobiology of overlap between ASD and SCZ. Understanding this overlap will allow for researchers, and eventually clinicians, to understand the factors that may make a child with ASD vulnerable to developing SCZ. Lay Summary Autism spectrum disorder and schizophrenia are distinct diagnoses, but people with autism and people with schizophrena share several characteristics. We review recent studies that have examined these areas of overlap, and discuss the kinds of studies we will need to better understand how these disorders are related. Understanding this will be important to help us identify which autistic children are at risk of developing schizophrenia." @default.
- W4200207813 created "2021-12-31" @default.
- W4200207813 creator A5050099223 @default.
- W4200207813 creator A5053558359 @default.
- W4200207813 creator A5061617553 @default.
- W4200207813 date "2021-12-29" @default.
- W4200207813 modified "2023-10-15" @default.
- W4200207813 title "Autism spectrum disorder and schizophrenia: An updated conceptual review" @default.
- W4200207813 cites W1090113287 @default.
- W4200207813 cites W157351644 @default.
- W4200207813 cites W1600233337 @default.
- W4200207813 cites W1851854755 @default.
- W4200207813 cites W1913218857 @default.
- W4200207813 cites W1927796084 @default.
- W4200207813 cites W1943343986 @default.
- W4200207813 cites W1963673462 @default.
- W4200207813 cites W1965263998 @default.
- W4200207813 cites W1968696473 @default.
- W4200207813 cites W1969833165 @default.
- W4200207813 cites W1970151545 @default.
- W4200207813 cites W1973140577 @default.
- W4200207813 cites W1982282485 @default.
- W4200207813 cites W1989101466 @default.
- W4200207813 cites W1990007146 @default.
- W4200207813 cites W1993890839 @default.
- W4200207813 cites W2001225869 @default.
- W4200207813 cites W2001251954 @default.
- W4200207813 cites W2003301148 @default.
- W4200207813 cites W2003969343 @default.
- W4200207813 cites W2005933475 @default.
- W4200207813 cites W2007544773 @default.
- W4200207813 cites W2012203722 @default.
- W4200207813 cites W2013655480 @default.
- W4200207813 cites W2015378973 @default.
- W4200207813 cites W2020926765 @default.
- W4200207813 cites W2024341316 @default.
- W4200207813 cites W2031788316 @default.
- W4200207813 cites W2034197594 @default.
- W4200207813 cites W2034471184 @default.
- W4200207813 cites W2038648070 @default.
- W4200207813 cites W2040451230 @default.
- W4200207813 cites W2042981671 @default.
- W4200207813 cites W2045227722 @default.
- W4200207813 cites W2047184993 @default.
- W4200207813 cites W2055926664 @default.
- W4200207813 cites W2057024402 @default.
- W4200207813 cites W2057932313 @default.
- W4200207813 cites W2067541402 @default.
- W4200207813 cites W2076224650 @default.
- W4200207813 cites W2077888736 @default.
- W4200207813 cites W2079869305 @default.
- W4200207813 cites W2084009541 @default.
- W4200207813 cites W2090495936 @default.
- W4200207813 cites W2090877723 @default.
- W4200207813 cites W2092522680 @default.
- W4200207813 cites W2093410327 @default.
- W4200207813 cites W2099388920 @default.
- W4200207813 cites W2101357408 @default.
- W4200207813 cites W2103627440 @default.
- W4200207813 cites W2103792319 @default.
- W4200207813 cites W2105857082 @default.
- W4200207813 cites W2106095152 @default.
- W4200207813 cites W2108450591 @default.
- W4200207813 cites W2110833962 @default.
- W4200207813 cites W2113435725 @default.
- W4200207813 cites W2113758182 @default.
- W4200207813 cites W2116470766 @default.
- W4200207813 cites W2116753165 @default.
- W4200207813 cites W2128639372 @default.
- W4200207813 cites W2128662472 @default.
- W4200207813 cites W2132567347 @default.
- W4200207813 cites W2132915420 @default.
- W4200207813 cites W2134418158 @default.
- W4200207813 cites W2134549690 @default.
- W4200207813 cites W2136981862 @default.
- W4200207813 cites W2137554955 @default.
- W4200207813 cites W2139738525 @default.
- W4200207813 cites W2141822795 @default.
- W4200207813 cites W2144535302 @default.
- W4200207813 cites W2145215768 @default.
- W4200207813 cites W2147546041 @default.
- W4200207813 cites W2148855381 @default.
- W4200207813 cites W2152079029 @default.
- W4200207813 cites W2153123253 @default.
- W4200207813 cites W2153240993 @default.
- W4200207813 cites W2156691676 @default.
- W4200207813 cites W2158411733 @default.
- W4200207813 cites W2161253 @default.
- W4200207813 cites W2162460585 @default.
- W4200207813 cites W2164138343 @default.
- W4200207813 cites W2165083041 @default.
- W4200207813 cites W2170703764 @default.
- W4200207813 cites W2176255924 @default.
- W4200207813 cites W2177407472 @default.
- W4200207813 cites W2202453598 @default.
- W4200207813 cites W2207583083 @default.
- W4200207813 cites W2250864655 @default.
- W4200207813 cites W2289275140 @default.