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• W4200208034 abstract "The pathogenesis and clinical manifestations of the multisystem inflammatory syndrome in children (MIS-C) has not yet been fully elucidated and there is no clear consensus on its treatment yet.To evaluate our patients diagnosed with MIS-C and present them to the literature in order to contribute to the better understanding of this new disease, which entered paediatric practice with the SARS-CoV-2 peak.In this study, 17 MIS-C cases diagnosed according to the Centers for Disease Control and Prevention criteria were included.Of the patients, 7 (41.2%) had a comorbidity. Gastrointestinal system involvement was the most prominent in the patients (70.6%). Laparotomy was performed in 3 patients due to acute abdomen. Two patients had neurological involvement. Of the patients, 15 (88.2%) received intravenous immunoglobulin and 13 (76.5%) received both intravenous immunoglobulin and methylprednisolone. Two patients received invasive mechanical ventilation and 4 patients received high flow rate nasal cannula oxygen therapy. One of our patients who needed invasive mechanical ventilation and high vasoactive-inotrope support died despite all supportive treatments including plasmapheresis and extracorporeal membrane oxygenation.MIS-C picture can have a fatal course and may present with severe gastrointestinal and neurological signs. Unnecessary laparotomy should be avoided." @default.
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• W4200208034 date "2021-09-06" @default.
• W4200208034 modified "2023-10-17" @default.
• W4200208034 title "COVID-19-associated multisystem inflammatory syndrome in children: Experiences of three centres in Turkey" @default.
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• W4200208034 doi "https://doi.org/10.1093/mr/roab042" @default.
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