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- W4200208087 abstract "In the past decade, a great effort has been devoted to develop new biosensor platforms for the detection of a wide range of analytes. Among the various approaches, magneto-DNA assay platforms have received extended interest for high sensitive and specific detection of targets with a simultaneous manipulation capacity. Here, using nitrogen-vacancy quantum centers in diamond as transducers for magnetic nanotags (MNTs), a hydrogel-based, multiplexed magneto-DNA assay is presented. Near-background-free sensing with diamond-based imaging combined with noninvasive control of chemically robust nanotags renders it a promising platform for applications in medical diagnostics, life science, and pharmaceutical drug research. To demonstrate its potential for practical applications, we employed the sensor platform in the sandwich DNA hybridization process and achieved a limit of detection in the attomolar range with single-base mismatch differentiation." @default.
- W4200208087 created "2021-12-31" @default.
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- W4200208087 date "2021-12-13" @default.
- W4200208087 modified "2023-10-18" @default.
- W4200208087 title "Multiplexed sensing of biomolecules with optically detected magnetic resonance of nitrogen-vacancy centers in diamond" @default.
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- W4200208087 doi "https://doi.org/10.1073/pnas.2112664118" @default.
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