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- W4200212028 abstract "More than 40% of adults in the United States suffer from obesity. Obesity is inextricably linked to many chronic illnesses like type-2 diabetes mellitus, hypertension, hyperlipidemia, heart disease, sleep apnea, stroke, and cancers. When used in combination with lifestyle modifications, pharmacotherapy has a vital role in treating obesity and improves short-term and long-term outcomes. A growing number of physicians are now interested in obesity medicine, and many of them are seeking guidance on how to treat complex patients with co-morbidities. This review provides a practical guide to the use of anti-obesity medications across various obesity-related comorbidities. It provides a general review of the currently approved anti-obesity medications and effective combinations. It discusses the highlights of the major trials and recent studies assessing the benefits of anti-obesity medications in comorbid conditions such as type-2 diabetes mellitus, psychiatric disorders, cardiovascular diseases, hypertension, renal diseases, and liver diseases. This review briefly examines the aspects of recognizing and addressing iatrogenic weight gain; discusses the precautions and prescribing considerations of anti-obesity medications, including side effects and possible dose adjustments in various comorbid conditions; and provides an expert opinion on an individualized choice of the best anti-obesity medication." @default.
- W4200212028 created "2021-12-31" @default.
- W4200212028 creator A5028635435 @default.
- W4200212028 creator A5063565461 @default.
- W4200212028 date "2021-12-09" @default.
- W4200212028 modified "2023-09-30" @default.
- W4200212028 title "Pharmacotherapy of obesity in complex diseases" @default.
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- W4200212028 doi "https://doi.org/10.1111/cob.12497" @default.
- W4200212028 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34889046" @default.
- W4200212028 hasPublicationYear "2021" @default.
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