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- W4200225503 abstract "Herein, we report a cobalt-catalyzed α-hydroxymethylation of amides with methanol under mild conditions. Using CoCl2·6H2O as an inexpensive and efficient catalyst, some important bioactive β-hydroxyamides were obtained in moderate to excellent yields. The developed method features a wide substrate scope and good functional group tolerance. In addition, anticholinergic tropicamide was easily synthesized in this way." @default.
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- W4200225503 date "2022-01-01" @default.
- W4200225503 modified "2023-10-13" @default.
- W4200225503 title "Cobalt-catalyzed direct α-hydroxymethylation of amides with methanol as a C1 source" @default.
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- W4200225503 doi "https://doi.org/10.1039/d1cc06501g" @default.
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