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- W4200242296 endingPage "107036" @default.
- W4200242296 startingPage "107036" @default.
- W4200242296 abstract "• The present study explains how electric and magnetic fields affect canalicular fluid motion in bone. • Electromagnetic fields modulates osteogenic stimulus. • Canalicular fluid is considered as a mechanobiological stimulus for new bone formation. • Electric field enhances fluid motion in porous bone with pathological conditions as well. Osteoporosis, bone-muscle disuse, and long-term exposure to space microgravity cause bone loss and promote bone fractures. Therapeutic devices and interventions for the prevention of bone loss and regulation of fracture healing are serious challenges for orthopaedic clinicians and researchers. Electromagnetic field exposure in combination with mechanical loading has the potential to prevent disuse bone loss as it promotes osteogenesis i.e., new bone formation. Loading-induced fluid motion in lacunar space acts as a stimulus for osteo-activities. Nevertheless, how the electromagnetic field regulates biomechanical stimulus such as fluid motion required for osteogenesis within bone tissue is not well understood. Accordingly, this paper attempts to establish a mathematical model to investigate the role of electromagnetic fields to alter the cantilever bending-induced lacunar fluid flow behaviour. A more realistic curvy canalicular channel subjected to electrohydrodynamics (EHD) mechanism is modelled to study poromechanical and canalicular fluid flow parameters such as pore-pressure gradient, fluid velocity, wall shear, and streamline patterns. Computational results indicate that electromagnetic fields modulate the fluid motion required for osteogenic activities even in bone tissues with higher porosity and permeability. The present study explains how electromagnetic fields possibly modulate mechanobiological stimulus in bone tissue. Based on the outcomes, an optimal loading regimen along with the electromagnetic field can be selected to enhance osteogenic response to prevent and mitigate irreversible bone loss that occurred due to microgravity and disuse." @default.
- W4200242296 created "2021-12-31" @default.
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- W4200242296 date "2022-03-01" @default.
- W4200242296 modified "2023-10-16" @default.
- W4200242296 title "Electromagnetic field induced alterations in fluid flow through lacuno-canalicular system of bone" @default.
- W4200242296 cites W1236525511 @default.
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- W4200242296 cites W1954002341 @default.
- W4200242296 cites W1970071418 @default.
- W4200242296 cites W1984088518 @default.
- W4200242296 cites W1989629699 @default.
- W4200242296 cites W1991570657 @default.
- W4200242296 cites W1992567157 @default.
- W4200242296 cites W2007487852 @default.
- W4200242296 cites W2010542271 @default.
- W4200242296 cites W2012599742 @default.
- W4200242296 cites W2013792523 @default.
- W4200242296 cites W2015254160 @default.
- W4200242296 cites W2017988945 @default.
- W4200242296 cites W2020349769 @default.
- W4200242296 cites W2026480149 @default.
- W4200242296 cites W2033499704 @default.
- W4200242296 cites W2034387495 @default.
- W4200242296 cites W2036338634 @default.
- W4200242296 cites W2037642431 @default.
- W4200242296 cites W2040192152 @default.
- W4200242296 cites W2041428921 @default.
- W4200242296 cites W2045176560 @default.
- W4200242296 cites W2045199030 @default.
- W4200242296 cites W2046015771 @default.
- W4200242296 cites W2048736476 @default.
- W4200242296 cites W2054231167 @default.
- W4200242296 cites W2059163311 @default.
- W4200242296 cites W2060090654 @default.
- W4200242296 cites W2060471433 @default.
- W4200242296 cites W2075719804 @default.
- W4200242296 cites W2082649337 @default.
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- W4200242296 cites W2083991002 @default.
- W4200242296 cites W2090887134 @default.
- W4200242296 cites W2092871797 @default.
- W4200242296 cites W2105299711 @default.
- W4200242296 cites W2106370928 @default.
- W4200242296 cites W2133664160 @default.
- W4200242296 cites W2133981091 @default.
- W4200242296 cites W2141612242 @default.
- W4200242296 cites W2145937652 @default.
- W4200242296 cites W2152723687 @default.
- W4200242296 cites W2155736277 @default.
- W4200242296 cites W2162830045 @default.
- W4200242296 cites W2164116460 @default.
- W4200242296 cites W2164319357 @default.
- W4200242296 cites W2165371409 @default.
- W4200242296 cites W2166079767 @default.
- W4200242296 cites W2311061917 @default.
- W4200242296 cites W2392180684 @default.
- W4200242296 cites W2415373090 @default.
- W4200242296 cites W2523921501 @default.
- W4200242296 cites W2620669958 @default.
- W4200242296 cites W2738975979 @default.
- W4200242296 cites W2768585353 @default.
- W4200242296 cites W2770465687 @default.
- W4200242296 cites W2791862747 @default.
- W4200242296 cites W2800013010 @default.
- W4200242296 cites W2896042697 @default.
- W4200242296 cites W2902107237 @default.
- W4200242296 cites W2912016924 @default.
- W4200242296 cites W2933953398 @default.
- W4200242296 cites W2949101903 @default.
- W4200242296 cites W2949920813 @default.
- W4200242296 cites W2960288475 @default.
- W4200242296 cites W2964038013 @default.
- W4200242296 cites W2996813838 @default.
- W4200242296 cites W3006965103 @default.
- W4200242296 cites W3012178496 @default.
- W4200242296 cites W3024134379 @default.
- W4200242296 cites W3081089244 @default.
- W4200242296 cites W3091537125 @default.
- W4200242296 cites W4240048429 @default.
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- W4200242296 doi "https://doi.org/10.1016/j.ijmecsci.2021.107036" @default.
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