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- W4200247706 endingPage "15065" @default.
- W4200247706 startingPage "15052" @default.
- W4200247706 abstract "Black tea is one of the most popular beverages in the world, and numerous epidemiological studies have shown that drinking black tea is good for health. As a natural tea pigment formed during the fermentation of black tea, the content of theaflavins accounts for only 2-6% of the dry weight of black tea, but they have a great impact on the color and taste of black tea soup. Recently, a large number of studies have shown that theaflavins have a significant anticancer effect. In this Perspective, we first state the physical and chemical properties, separation and purification methods, and biological formation pathways of theaflavins and analyze their safety and oral bioavailability and the structure-activity relationship of their antioxidant and anticancer activities; then, we describe in detail their anticancer effect in vitro and in vivo and highlight their various molecular targets involved in cancer inhibition. The anticancer molecular targets of theaflavins are mainly cell-cycle regulatory proteins, apoptosis-related proteins, cell-migration-related proteins, and growth transcription factors. Finally, the possibility of developing new health-care food based on theaflavins is discussed. This Perspective is expected to provide a theoretical basis for the anticancer application of theaflavins in the future." @default.
- W4200247706 created "2021-12-31" @default.
- W4200247706 creator A5000562106 @default.
- W4200247706 creator A5035201433 @default.
- W4200247706 date "2021-12-08" @default.
- W4200247706 modified "2023-10-01" @default.
- W4200247706 title "Anticancer Effects and Molecular Target of Theaflavins from Black Tea Fermentation <i>in Vitro</i> and <i>in Vivo</i>" @default.
- W4200247706 cites W1183385771 @default.
- W4200247706 cites W15274736 @default.
- W4200247706 cites W1859306058 @default.
- W4200247706 cites W1868724776 @default.
- W4200247706 cites W1964691523 @default.
- W4200247706 cites W1965778553 @default.
- W4200247706 cites W1973430942 @default.
- W4200247706 cites W1987725373 @default.
- W4200247706 cites W1988174007 @default.
- W4200247706 cites W1990673132 @default.
- W4200247706 cites W1993347615 @default.
- W4200247706 cites W1994367078 @default.
- W4200247706 cites W1994886066 @default.
- W4200247706 cites W1995514723 @default.
- W4200247706 cites W1995847767 @default.
- W4200247706 cites W1997988956 @default.
- W4200247706 cites W2003579750 @default.
- W4200247706 cites W2005854408 @default.
- W4200247706 cites W2006612651 @default.
- W4200247706 cites W2006668405 @default.
- W4200247706 cites W2007468478 @default.
- W4200247706 cites W2008744726 @default.
- W4200247706 cites W2009749628 @default.
- W4200247706 cites W2011802324 @default.
- W4200247706 cites W2013060814 @default.
- W4200247706 cites W2013945303 @default.
- W4200247706 cites W2020916124 @default.
- W4200247706 cites W2022732654 @default.
- W4200247706 cites W2025727132 @default.
- W4200247706 cites W2026468168 @default.
- W4200247706 cites W2028527350 @default.
- W4200247706 cites W2030093136 @default.
- W4200247706 cites W2031713959 @default.
- W4200247706 cites W2031933070 @default.
- W4200247706 cites W2032136152 @default.
- W4200247706 cites W2037149829 @default.
- W4200247706 cites W2037735499 @default.
- W4200247706 cites W2042713890 @default.
- W4200247706 cites W2045752681 @default.
- W4200247706 cites W2048454527 @default.
- W4200247706 cites W2048937166 @default.
- W4200247706 cites W2050352050 @default.
- W4200247706 cites W2050695134 @default.
- W4200247706 cites W2050722080 @default.
- W4200247706 cites W2052683686 @default.
- W4200247706 cites W2061220034 @default.
- W4200247706 cites W2064115283 @default.
- W4200247706 cites W2065707909 @default.
- W4200247706 cites W2067823579 @default.
- W4200247706 cites W2078027217 @default.
- W4200247706 cites W2082370359 @default.
- W4200247706 cites W2085470409 @default.
- W4200247706 cites W2087358534 @default.
- W4200247706 cites W2088875824 @default.
- W4200247706 cites W2091750970 @default.
- W4200247706 cites W2094178208 @default.
- W4200247706 cites W2094280451 @default.
- W4200247706 cites W2094983273 @default.
- W4200247706 cites W2110292559 @default.
- W4200247706 cites W2116000012 @default.
- W4200247706 cites W2116147432 @default.
- W4200247706 cites W2124290816 @default.
- W4200247706 cites W2141884188 @default.
- W4200247706 cites W2144467901 @default.
- W4200247706 cites W2154177487 @default.
- W4200247706 cites W2160035633 @default.
- W4200247706 cites W2165229464 @default.
- W4200247706 cites W2166085918 @default.
- W4200247706 cites W2167593057 @default.
- W4200247706 cites W2167784424 @default.
- W4200247706 cites W2321082647 @default.
- W4200247706 cites W2513561128 @default.
- W4200247706 cites W2532914623 @default.
- W4200247706 cites W2556479552 @default.
- W4200247706 cites W2609343343 @default.
- W4200247706 cites W2621231337 @default.
- W4200247706 cites W2622666676 @default.
- W4200247706 cites W2730053957 @default.
- W4200247706 cites W2734270485 @default.
- W4200247706 cites W2799785234 @default.
- W4200247706 cites W2800376069 @default.
- W4200247706 cites W2889646458 @default.
- W4200247706 cites W2892790430 @default.
- W4200247706 cites W2898079638 @default.
- W4200247706 cites W2903367572 @default.
- W4200247706 cites W2951268602 @default.
- W4200247706 cites W2951435359 @default.
- W4200247706 cites W2983185796 @default.
- W4200247706 cites W3081740312 @default.
- W4200247706 cites W3092031307 @default.
- W4200247706 cites W3115362444 @default.