Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200248913> ?p ?o ?g. }
Showing items 1 to 68 of
68
with 100 items per page.
- W4200248913 endingPage "189" @default.
- W4200248913 startingPage "158" @default.
- W4200248913 abstract "Proteomics is a branch of molecular biology that deals with the identification and quantification of proteins in living objects, as well as the analysis of protein functions and their interactions.
 Proteomics is studied by proteins that are expressed in a given cell, tissue or organism over a period of time (under certain conditions).
 It is known that information about the primary structure of a protein (the sequence of amino acid residues in a protein) is contained in a structural gene in the form of a codon sequence (genetic code). On the other hand, less than 10% of genes are functionally active (expressed) in the somatic cells of our body. Moreover, a distinct tissue-specific expression of genes is observed. This, in turn, leads to the peculiarities of the qualitative composition of the synthesized proteins in various tissues. No less important is the fact that the total amount of proteins synthesized by our tissues is much greater than the total number of structural genes containing information about their original structure. This phenomenon is explained by the activity of such mechanisms as alternative splicing and a wide variety of post-translational peptide processing pathways (covalent modification of a polypeptide synthesized on the ribosome) in health and disease. Thus, even a brief review of the semantic content of the term proteomics indicates an extremely complex system of protein molecules in our body, which plays a fundamental role in maintaining homeostasis and is involved in the formation of adaptive responses in response to adverse changes in the internal and external environment." @default.
- W4200248913 created "2021-12-31" @default.
- W4200248913 creator A5003409746 @default.
- W4200248913 creator A5028997538 @default.
- W4200248913 creator A5056541165 @default.
- W4200248913 date "2021-12-14" @default.
- W4200248913 modified "2023-10-17" @default.
- W4200248913 title "Proteomics" @default.
- W4200248913 doi "https://doi.org/10.12775/jehs.2021.11.12.011" @default.
- W4200248913 hasPublicationYear "2021" @default.
- W4200248913 type Work @default.
- W4200248913 citedByCount "0" @default.
- W4200248913 crossrefType "journal-article" @default.
- W4200248913 hasAuthorship W4200248913A5003409746 @default.
- W4200248913 hasAuthorship W4200248913A5028997538 @default.
- W4200248913 hasAuthorship W4200248913A5056541165 @default.
- W4200248913 hasBestOaLocation W42002489131 @default.
- W4200248913 hasConcept C104317684 @default.
- W4200248913 hasConcept C105580179 @default.
- W4200248913 hasConcept C10853874 @default.
- W4200248913 hasConcept C137858568 @default.
- W4200248913 hasConcept C149364088 @default.
- W4200248913 hasConcept C194583182 @default.
- W4200248913 hasConcept C46111723 @default.
- W4200248913 hasConcept C54355233 @default.
- W4200248913 hasConcept C54458228 @default.
- W4200248913 hasConcept C55493867 @default.
- W4200248913 hasConcept C67705224 @default.
- W4200248913 hasConcept C70721500 @default.
- W4200248913 hasConcept C86803240 @default.
- W4200248913 hasConcept C88478588 @default.
- W4200248913 hasConcept C95444343 @default.
- W4200248913 hasConceptScore W4200248913C104317684 @default.
- W4200248913 hasConceptScore W4200248913C105580179 @default.
- W4200248913 hasConceptScore W4200248913C10853874 @default.
- W4200248913 hasConceptScore W4200248913C137858568 @default.
- W4200248913 hasConceptScore W4200248913C149364088 @default.
- W4200248913 hasConceptScore W4200248913C194583182 @default.
- W4200248913 hasConceptScore W4200248913C46111723 @default.
- W4200248913 hasConceptScore W4200248913C54355233 @default.
- W4200248913 hasConceptScore W4200248913C54458228 @default.
- W4200248913 hasConceptScore W4200248913C55493867 @default.
- W4200248913 hasConceptScore W4200248913C67705224 @default.
- W4200248913 hasConceptScore W4200248913C70721500 @default.
- W4200248913 hasConceptScore W4200248913C86803240 @default.
- W4200248913 hasConceptScore W4200248913C88478588 @default.
- W4200248913 hasConceptScore W4200248913C95444343 @default.
- W4200248913 hasIssue "12" @default.
- W4200248913 hasLocation W42002489131 @default.
- W4200248913 hasLocation W42002489132 @default.
- W4200248913 hasOpenAccess W4200248913 @default.
- W4200248913 hasPrimaryLocation W42002489131 @default.
- W4200248913 hasRelatedWork W1496254511 @default.
- W4200248913 hasRelatedWork W2074534662 @default.
- W4200248913 hasRelatedWork W2101199302 @default.
- W4200248913 hasRelatedWork W2167658041 @default.
- W4200248913 hasRelatedWork W2206864390 @default.
- W4200248913 hasRelatedWork W2318486985 @default.
- W4200248913 hasRelatedWork W2460850269 @default.
- W4200248913 hasRelatedWork W2519557303 @default.
- W4200248913 hasRelatedWork W2606640796 @default.
- W4200248913 hasRelatedWork W2996361559 @default.
- W4200248913 hasVolume "11" @default.
- W4200248913 isParatext "false" @default.
- W4200248913 isRetracted "false" @default.
- W4200248913 workType "article" @default.