Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200269314> ?p ?o ?g. }
- W4200269314 endingPage "e0261208" @default.
- W4200269314 startingPage "e0261208" @default.
- W4200269314 abstract "Purpose Changes in cerebral cortical regions occur in HIV-infected patients, even in those with mild neurocognitive disorders. Working memory / attention is one of the most affected cognitive domain in these patients, worsening their quality of life. Our objective was to assess whether cortical thickness differs between HIV-infected patients with and without working memory deficit. Methods Forty-one adult HIV-infected patients with and without working memory deficit were imaged on a 1.5 T scanner. Working memory deficit was classified by composite Z scores for performance on the Digits and Letter-Number Sequencing subtests of the Wechsler Adult Intelligence Scale (third edition; WAIS-III). Cortical thickness was determined using FreeSurfer software. Differences in mean cortical thickness between groups, corrected for multiple comparisons using Monte-Carlo simulation, were examined using the query design estimate contrast tool of the FreeSurfer software. Results Greater cortical thickness in left pars opercularis of the inferior frontal gyrus, and rostral and caudal portions of the left middle frontal gyrus (cluster 1; p = .004), and left superior frontal gyrus (cluster 2; p = .004) was observed in HIV-infected patients with working memory deficit compared with those without such deficit. Negative correlations were found between WAIS-III–based Z scores and cortical thickness in the two clusters (cluster 1: ρ = –0.59; cluster 2: ρ = –0.47). Conclusion HIV-infected patients with working memory deficit have regions of greater thickness in the left frontal cortices compared with those without such deficit, which may reflect increased synaptic contacts and/or an inflammatory response related to the damage caused by HIV infection." @default.
- W4200269314 created "2021-12-31" @default.
- W4200269314 creator A5002246849 @default.
- W4200269314 creator A5003991448 @default.
- W4200269314 creator A5004745319 @default.
- W4200269314 creator A5006539466 @default.
- W4200269314 creator A5020581975 @default.
- W4200269314 creator A5026714604 @default.
- W4200269314 creator A5038152431 @default.
- W4200269314 creator A5046905510 @default.
- W4200269314 creator A5061222459 @default.
- W4200269314 creator A5070836177 @default.
- W4200269314 creator A5080275619 @default.
- W4200269314 date "2021-12-10" @default.
- W4200269314 modified "2023-09-25" @default.
- W4200269314 title "Preliminary comparative study of cortical thickness in HIV-infected patients with and without working memory deficit" @default.
- W4200269314 cites W1584481215 @default.
- W4200269314 cites W1591966483 @default.
- W4200269314 cites W1965771641 @default.
- W4200269314 cites W1970866005 @default.
- W4200269314 cites W1978613454 @default.
- W4200269314 cites W1982422745 @default.
- W4200269314 cites W1989087267 @default.
- W4200269314 cites W1996496705 @default.
- W4200269314 cites W2000366874 @default.
- W4200269314 cites W2001355988 @default.
- W4200269314 cites W2032144844 @default.
- W4200269314 cites W2035155363 @default.
- W4200269314 cites W2037303541 @default.
- W4200269314 cites W2039742816 @default.
- W4200269314 cites W2052247425 @default.
- W4200269314 cites W2053739443 @default.
- W4200269314 cites W2057261851 @default.
- W4200269314 cites W2066704111 @default.
- W4200269314 cites W2079058264 @default.
- W4200269314 cites W2085136414 @default.
- W4200269314 cites W2093554933 @default.
- W4200269314 cites W2096065792 @default.
- W4200269314 cites W2097671052 @default.
- W4200269314 cites W2098496942 @default.
- W4200269314 cites W2099556941 @default.
- W4200269314 cites W2101135654 @default.
- W4200269314 cites W2110208125 @default.
- W4200269314 cites W2111446187 @default.
- W4200269314 cites W2115118763 @default.
- W4200269314 cites W2122373522 @default.
- W4200269314 cites W2127548870 @default.
- W4200269314 cites W2129859683 @default.
- W4200269314 cites W2130599091 @default.
- W4200269314 cites W2136021734 @default.
- W4200269314 cites W2142202785 @default.
- W4200269314 cites W2142727674 @default.
- W4200269314 cites W2150440918 @default.
- W4200269314 cites W2151227755 @default.
- W4200269314 cites W2170457399 @default.
- W4200269314 cites W2174199416 @default.
- W4200269314 cites W2266384028 @default.
- W4200269314 cites W2329328415 @default.
- W4200269314 cites W2528822478 @default.
- W4200269314 cites W2538425715 @default.
- W4200269314 cites W2583330132 @default.
- W4200269314 cites W2735442096 @default.
- W4200269314 cites W2776130467 @default.
- W4200269314 cites W2793565742 @default.
- W4200269314 cites W2896204498 @default.
- W4200269314 cites W3036967234 @default.
- W4200269314 cites W4232473916 @default.
- W4200269314 doi "https://doi.org/10.1371/journal.pone.0261208" @default.
- W4200269314 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34890434" @default.
- W4200269314 hasPublicationYear "2021" @default.
- W4200269314 type Work @default.
- W4200269314 citedByCount "1" @default.
- W4200269314 countsByYear W42002693142022 @default.
- W4200269314 crossrefType "journal-article" @default.
- W4200269314 hasAuthorship W4200269314A5002246849 @default.
- W4200269314 hasAuthorship W4200269314A5003991448 @default.
- W4200269314 hasAuthorship W4200269314A5004745319 @default.
- W4200269314 hasAuthorship W4200269314A5006539466 @default.
- W4200269314 hasAuthorship W4200269314A5020581975 @default.
- W4200269314 hasAuthorship W4200269314A5026714604 @default.
- W4200269314 hasAuthorship W4200269314A5038152431 @default.
- W4200269314 hasAuthorship W4200269314A5046905510 @default.
- W4200269314 hasAuthorship W4200269314A5061222459 @default.
- W4200269314 hasAuthorship W4200269314A5070836177 @default.
- W4200269314 hasAuthorship W4200269314A5080275619 @default.
- W4200269314 hasBestOaLocation W42002693141 @default.
- W4200269314 hasConcept C15744967 @default.
- W4200269314 hasConcept C169760540 @default.
- W4200269314 hasConcept C169900460 @default.
- W4200269314 hasConcept C172467417 @default.
- W4200269314 hasConcept C21963081 @default.
- W4200269314 hasConcept C2775956885 @default.
- W4200269314 hasConcept C2779369059 @default.
- W4200269314 hasConcept C2779991468 @default.
- W4200269314 hasConcept C548259974 @default.
- W4200269314 hasConcept C71924100 @default.
- W4200269314 hasConcept C89798072 @default.
- W4200269314 hasConceptScore W4200269314C15744967 @default.