FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200272816> ?p ?o ?g. }

• W4200272816 endingPage "e0260730" @default.
• W4200272816 startingPage "e0260730" @default.
• W4200272816 abstract "This study aimed to clarify the etiologic factors predicting acute ocular progression in SJS/TEN, and identify patients who require immediate and intensive ophthalmological treatment. We previously conducted two Japanese Surveys of SJS/TEN (i.e., cases arising between 2005-2007 and between 2008-2010), and obtained the medical records, including detailed dermatological and ophthalmological findings, of 230 patients. Acute ocular severity was evaluated as none, mild, severe, and very severe. A multi-state model assuming the Markov process based on the Cox proportional hazards model was used to elucidate the specific factors affecting the acute ocular progression. Our findings revealed that of the total 230 patients, 23 (24%) of 97 cases that were mild at initial presentation worsened to severe/very severe. Acute ocular progression developed within 3 weeks from disease onset. Exposure to nonsteroidal anti-inflammatory drugs (NSAIDs) and younger patient age were found to be statistically significant for the progression of ocular severity from mild to severe/very severe [hazard ratio (HR) 3.83; 95% confidence interval (CI) 1.48 to 9.91] and none to severe/very severe [HR 0.98; 95% CI 0.97 to 0.99], respectively. The acute ocular severity score at worst-condition was found to be significantly correlated with ocular sequelae. Thus, our detailed findings on acute ocular progression revealed that in 24% of SJS/TEN cases with ocular involvement, ocular severity progresses even after initiating intensive treatment, and that in younger-age patients with a history of exposure to NSAIDs, very strict attention must be given to their ophthalmological appearances." @default.
• W4200272816 created "2021-12-31" @default.
• W4200272816 creator A5000736594 @default.
• W4200272816 creator A5016215778 @default.
• W4200272816 creator A5020320910 @default.
• W4200272816 creator A5029687156 @default.
• W4200272816 creator A5032420302 @default.
• W4200272816 creator A5041093478 @default.
• W4200272816 creator A5044882193 @default.
• W4200272816 creator A5045999870 @default.
• W4200272816 creator A5057956616 @default.
• W4200272816 creator A5064533789 @default.
• W4200272816 creator A5076485455 @default.
• W4200272816 creator A5080884788 @default.
• W4200272816 creator A9999999999 @default.
• W4200272816 date "2021-12-23" @default.
• W4200272816 modified "2023-10-13" @default.
• W4200272816 title "Multi-state model for predicting ocular progression in acute Stevens-Johnson syndrome/toxic epidermal necrolysis" @default.
• W4200272816 cites W1563152276 @default.
• W4200272816 cites W1871125706 @default.
• W4200272816 cites W1973545887 @default.
• W4200272816 cites W1978846604 @default.
• W4200272816 cites W1979259860 @default.
• W4200272816 cites W2024517968 @default.
• W4200272816 cites W2031301975 @default.
• W4200272816 cites W2045391651 @default.
• W4200272816 cites W2055107758 @default.
• W4200272816 cites W2057847137 @default.
• W4200272816 cites W2067665433 @default.
• W4200272816 cites W2072064959 @default.
• W4200272816 cites W2086171508 @default.
• W4200272816 cites W2088229392 @default.
• W4200272816 cites W2115832251 @default.
• W4200272816 cites W2130020008 @default.
• W4200272816 cites W2140726051 @default.
• W4200272816 cites W2150272490 @default.
• W4200272816 cites W2158770829 @default.
• W4200272816 cites W2172138398 @default.
• W4200272816 cites W2317624504 @default.
• W4200272816 cites W2419735139 @default.
• W4200272816 cites W2591878983 @default.
• W4200272816 cites W2764130179 @default.
• W4200272816 cites W2782356873 @default.
• W4200272816 cites W2884765514 @default.
• W4200272816 cites W4244548826 @default.
• W4200272816 doi "https://doi.org/10.1371/journal.pone.0260730" @default.
• W4200272816 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34941887" @default.
• W4200272816 hasPublicationYear "2021" @default.
• W4200272816 type Work @default.
• W4200272816 citedByCount "3" @default.
• W4200272816 countsByYear W42002728162022 @default.
• W4200272816 countsByYear W42002728162023 @default.
• W4200272816 crossrefType "journal-article" @default.
• W4200272816 hasAuthorship W4200272816A5000736594 @default.
• W4200272816 hasAuthorship W4200272816A5016215778 @default.
• W4200272816 hasAuthorship W4200272816A5020320910 @default.
• W4200272816 hasAuthorship W4200272816A5029687156 @default.
• W4200272816 hasAuthorship W4200272816A5032420302 @default.
• W4200272816 hasAuthorship W4200272816A5041093478 @default.
• W4200272816 hasAuthorship W4200272816A5044882193 @default.
• W4200272816 hasAuthorship W4200272816A5045999870 @default.
• W4200272816 hasAuthorship W4200272816A5057956616 @default.
• W4200272816 hasAuthorship W4200272816A5064533789 @default.
• W4200272816 hasAuthorship W4200272816A5076485455 @default.
• W4200272816 hasAuthorship W4200272816A5080884788 @default.
• W4200272816 hasAuthorship W4200272816A9999999999 @default.
• W4200272816 hasBestOaLocation W42002728161 @default.
• W4200272816 hasConcept C126322002 @default.
• W4200272816 hasConcept C16005928 @default.
• W4200272816 hasConcept C187212893 @default.
• W4200272816 hasConcept C195910791 @default.
• W4200272816 hasConcept C207103383 @default.
• W4200272816 hasConcept C2778484676 @default.
• W4200272816 hasConcept C2780664588 @default.
• W4200272816 hasConcept C44249647 @default.
• W4200272816 hasConcept C50382708 @default.
• W4200272816 hasConcept C71924100 @default.
• W4200272816 hasConceptScore W4200272816C126322002 @default.
• W4200272816 hasConceptScore W4200272816C16005928 @default.
• W4200272816 hasConceptScore W4200272816C187212893 @default.
• W4200272816 hasConceptScore W4200272816C195910791 @default.
• W4200272816 hasConceptScore W4200272816C207103383 @default.
• W4200272816 hasConceptScore W4200272816C2778484676 @default.
• W4200272816 hasConceptScore W4200272816C2780664588 @default.
• W4200272816 hasConceptScore W4200272816C44249647 @default.
• W4200272816 hasConceptScore W4200272816C50382708 @default.
• W4200272816 hasConceptScore W4200272816C71924100 @default.
• W4200272816 hasFunder F4320311405 @default.
• W4200272816 hasFunder F4320320912 @default.
• W4200272816 hasFunder F4320321945 @default.
• W4200272816 hasIssue "12" @default.
• W4200272816 hasLocation W42002728161 @default.
• W4200272816 hasLocation W42002728162 @default.
• W4200272816 hasLocation W42002728163 @default.
• W4200272816 hasLocation W42002728164 @default.
• W4200272816 hasOpenAccess W4200272816 @default.
• W4200272816 hasPrimaryLocation W42002728161 @default.
• W4200272816 hasRelatedWork W2036037138 @default.

• next