FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200281805> ?p ?o ?g. }

• W4200281805 endingPage "1451" @default.
• W4200281805 startingPage "1444" @default.
• W4200281805 abstract "The ability to functionalize gold nanoparticle surfaces with target ligands is integral to developing effective nanosystems for biomedical applications, ranging from point-of-care diagnostic devices to site-specific cancer therapies. By forming strong covalent bonds with gold, thiol functionalities can easily link molecules of interest to nanoparticle surfaces. Unfortunately, thiols are inherently prone to oxidative degradation in many biologically relevant conditions, which limits their broader use as surface ligands in commercial assays. Recently, N-heterocyclic carbene (NHC) ligands emerged as a promising alternative to thiols since initial reports demonstrated their remarkable stability against ligand displacement and stronger metal–ligand bonds. This work explores the long-term stability of NHC-functionalized gold nanoparticles suspended in five common biological media: phosphate-buffered saline, tris-glycine potassium buffer, tris-glycine potassium magnesium buffer, cell culture media, and human serum. The NHCs on gold nanoparticles were probed with surface-enhanced Raman spectroscopy (SERS) and X-ray photoelectron spectroscopy (XPS). SERS is useful for monitoring the degradation of surface-bound species because the resulting vibrational modes are highly sensitive to changes in ligand adsorption. Our measurements indicate that imidazole-based NHCs remain stable on gold nanoparticles over the 21 days of examination in all tested environments, with no observed change in the molecule’s SERS signature, XPS response, or UV–vis plasmon band." @default.
• W4200281805 created "2021-12-31" @default.
• W4200281805 creator A5007533515 @default.
• W4200281805 creator A5032112088 @default.
• W4200281805 creator A5039863397 @default.
• W4200281805 creator A5068060325 @default.
• W4200281805 creator A5069048531 @default.
• W4200281805 creator A5076841408 @default.
• W4200281805 creator A5077658490 @default.
• W4200281805 creator A5090630031 @default.
• W4200281805 date "2021-12-17" @default.
• W4200281805 modified "2023-10-17" @default.
• W4200281805 title "<i>N</i>-Heterocyclic Carbene Ligand Stability on Gold Nanoparticles in Biological Media" @default.
• W4200281805 cites W1967140324 @default.
• W4200281805 cites W1967253297 @default.
• W4200281805 cites W1969681915 @default.
• W4200281805 cites W1995608045 @default.
• W4200281805 cites W2000883834 @default.
• W4200281805 cites W2003555872 @default.
• W4200281805 cites W2011705292 @default.
• W4200281805 cites W2020451212 @default.
• W4200281805 cites W2027670638 @default.
• W4200281805 cites W2030634530 @default.
• W4200281805 cites W2034383665 @default.
• W4200281805 cites W2034883681 @default.
• W4200281805 cites W2039471593 @default.
• W4200281805 cites W2048828341 @default.
• W4200281805 cites W2052566608 @default.
• W4200281805 cites W2068236479 @default.
• W4200281805 cites W2077625608 @default.
• W4200281805 cites W2078820160 @default.
• W4200281805 cites W2092866119 @default.
• W4200281805 cites W2094938672 @default.
• W4200281805 cites W2162886716 @default.
• W4200281805 cites W2166806803 @default.
• W4200281805 cites W2238450501 @default.
• W4200281805 cites W2320112174 @default.
• W4200281805 cites W2414781026 @default.
• W4200281805 cites W2417953440 @default.
• W4200281805 cites W2472551131 @default.
• W4200281805 cites W2509333775 @default.
• W4200281805 cites W2523119479 @default.
• W4200281805 cites W2528043896 @default.
• W4200281805 cites W2555945825 @default.
• W4200281805 cites W2586185458 @default.
• W4200281805 cites W2591864733 @default.
• W4200281805 cites W2600647061 @default.
• W4200281805 cites W2605793152 @default.
• W4200281805 cites W2753501699 @default.
• W4200281805 cites W2772713983 @default.
• W4200281805 cites W2784537151 @default.
• W4200281805 cites W2791375536 @default.
• W4200281805 cites W2800777294 @default.
• W4200281805 cites W2805289333 @default.
• W4200281805 cites W2808221518 @default.
• W4200281805 cites W2850142515 @default.
• W4200281805 cites W2891887198 @default.
• W4200281805 cites W2896399839 @default.
• W4200281805 cites W2926036315 @default.
• W4200281805 cites W2943833909 @default.
• W4200281805 cites W2970930132 @default.
• W4200281805 cites W3008183976 @default.
• W4200281805 cites W3036637617 @default.
• W4200281805 cites W3036983622 @default.
• W4200281805 cites W3088863313 @default.
• W4200281805 cites W3093860619 @default.
• W4200281805 cites W3118841922 @default.
• W4200281805 cites W3130483342 @default.
• W4200281805 cites W3131436209 @default.
• W4200281805 cites W3139157332 @default.
• W4200281805 cites W3143347120 @default.
• W4200281805 cites W3158822905 @default.
• W4200281805 cites W3176631754 @default.
• W4200281805 doi "https://doi.org/10.1021/acsomega.1c06168" @default.
• W4200281805 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/35036806" @default.
• W4200281805 hasPublicationYear "2021" @default.
• W4200281805 type Work @default.
• W4200281805 citedByCount "9" @default.
• W4200281805 countsByYear W42002818052022 @default.
• W4200281805 countsByYear W42002818052023 @default.
• W4200281805 crossrefType "journal-article" @default.
• W4200281805 hasAuthorship W4200281805A5007533515 @default.
• W4200281805 hasAuthorship W4200281805A5032112088 @default.
• W4200281805 hasAuthorship W4200281805A5039863397 @default.
• W4200281805 hasAuthorship W4200281805A5068060325 @default.
• W4200281805 hasAuthorship W4200281805A5069048531 @default.
• W4200281805 hasAuthorship W4200281805A5076841408 @default.
• W4200281805 hasAuthorship W4200281805A5077658490 @default.
• W4200281805 hasAuthorship W4200281805A5090630031 @default.
• W4200281805 hasBestOaLocation W42002818051 @default.
• W4200281805 hasConcept C104819515 @default.
• W4200281805 hasConcept C116569031 @default.
• W4200281805 hasConcept C120665830 @default.
• W4200281805 hasConcept C121332964 @default.
• W4200281805 hasConcept C127413603 @default.
• W4200281805 hasConcept C155672457 @default.
• W4200281805 hasConcept C169573571 @default.
• W4200281805 hasConcept C170493617 @default.

• next