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- W4200285087 abstract "The recapitulation of human developmental processes and pathological manifestations requires access to specific cell types and precursor stages during embryogenesis and disease. Here, we describe a scalable in vitro differentiation protocol to guide human pluripotent stem cells stepwise into pancreatic duct-like organoids. The protocol mimics pancreatic duct development and was successfully used to model the onset and progression of pancreatic ductal adenocarcinoma; the approach is suitable for multiple downstream applications. However, the protocol is cost- and time-intensive. For complete details on the use and execution of this protocol, please refer to Breunig et al. (2021)." @default.
- W4200285087 created "2021-12-31" @default.
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- W4200285087 date "2021-12-01" @default.
- W4200285087 modified "2023-09-30" @default.
- W4200285087 title "Differentiation of human pluripotent stem cells into pancreatic duct-like organoids" @default.
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- W4200285087 doi "https://doi.org/10.1016/j.xpro.2021.100913" @default.
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