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- W4200289869 abstract "Ethnobotanical practices have a rich history and have increasingly been recognized for their contributions to traditional medical practice. The ethnobotanical use of the Calabar bean as a trial by ordeal eventually led to the discovery of physostigmine. Physostigmine is an organic carbamate with significant effects on human physiology. It has been used for treatment of myriad medical conditions and was at one point a frequent adjuvant for the reversal of obtundation. Its use in this context was associated with rare fatalities. The appropriate medical indications for the recommended use of this antidote were, and continue to be, heavily debated among medical toxicologists. This chapter discusses this controversial yet highly effective antidote including its discovery, its recommended indications, and contraindications in modern medicine." @default.
- W4200289869 created "2021-12-31" @default.
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- W4200289869 date "2022-01-01" @default.
- W4200289869 modified "2023-09-23" @default.
- W4200289869 title "Physostigmine" @default.
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- W4200289869 doi "https://doi.org/10.1016/b978-0-12-822218-8.00059-4" @default.
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