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- W4200289898 abstract "Skin and Soft Tissue infections (SSTIs) have imposed substantial economic and clinical burdens on the world. The growing prevalence of SSTIs is due in large part to Methicillin-Resistant S. aureus (MRSA), known for its notorious multidrug resistance and virulence. The recent emergence of vancomycin-resistant isolates promoted the exploration for non-inferior and safe alternatives. In this work, an overview of MRSA-induced SSTIs will be provided, followed by a review of the mechanism of action, clinical efficacy, adverse effects of two potential candidates, namely ceftaroline and linezolid. Investigations on the exact mechanism of linezolid translation arrest, linezolid-associated neuropathy, and pharmacoeconomic comparison between linezolid and ceftaroline are expected in future studies." @default.
- W4200289898 created "2021-12-31" @default.
- W4200289898 creator A5043928035 @default.
- W4200289898 date "2021-10-29" @default.
- W4200289898 modified "2023-09-29" @default.
- W4200289898 title "On the Treatment of MRSA Skin and Soft Tissue Infection with Ceftaroline and Linezolid" @default.
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- W4200289898 doi "https://doi.org/10.1145/3500931.3500988" @default.
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