FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200309967> ?p ?o ?g. }

• W4200309967 abstract "Abstract Context Hyperglycemia is a common complication of Cushing syndrome (CS). Objective We aimed to determine the impact of curative procedure on hyperglycemia and its management in patients with CS. Methods This retrospective longitudinal cohort study took place 2000 to 2019 in a referral center among adults with endogenous CS and hyperglycemia. Main outcome measures included glycated hemoglobin A1c (HbA1c), intensity of hyperglycemia therapy, and improvement of hyperglycemia. Results In 174 patients with CS (pituitary in 106, ectopic in 25, adrenal in 43), baseline median HbA1c was 6.9% (range, 4.9-13.1), with 41 (24%) patients not on any therapy for hyperglycemia, 93 (52%) on oral medications, and 64 (37%) on insulin (median daily units of 58; range, 10-360). Following CS remission, at the end of follow-up (median 10.5 months), 37 (21%) patients demonstrated resolution of hyperglycemia, 82 (47%) demonstrated improvement, and 55 (32%) had no change or worsening in hyperglycemia. At the end of follow-up, HbA1c decreased by 0.84% (P &lt; .001) and daily insulin dose decreased by a mean of 30 units (P &lt; .001). Biochemical hypercortisolism severity score (severe vs moderate/mild: odds ratio [OR] of 2.4 [95% CI, 1.1-4.9]), and CS subtype (nonadrenal vs adrenal: OR of 2.9 [95% CI, 1.3-6.4]), but not type of hyperglycemia (diabetes vs prediabetes: OR of 2.1 [0.9-4.9]) were associated with hyperglycemia improvement at the end of follow-up. Conclusion Two-thirds of patients with CS and hyperglycemia demonstrate resolution or improvement of hyperglycemia after a curative procedure. Close monitoring during CS recovery is needed to ensure appropriate therapy modification." @default.
• W4200309967 created "2021-12-31" @default.
• W4200309967 creator A5001416815 @default.
• W4200309967 creator A5025934150 @default.
• W4200309967 creator A5034012396 @default.
• W4200309967 creator A5058425019 @default.
• W4200309967 creator A5058935003 @default.
• W4200309967 creator A5072823303 @default.
• W4200309967 creator A5079316241 @default.
• W4200309967 creator A5088450261 @default.
• W4200309967 date "2021-12-02" @default.
• W4200309967 modified "2023-10-17" @default.
• W4200309967 title "The Effect of Curative Treatment on Hyperglycemia in Patients With Cushing Syndrome" @default.
• W4200309967 cites W1680099832 @default.
• W4200309967 cites W1945278090 @default.
• W4200309967 cites W1988096315 @default.
• W4200309967 cites W1990995386 @default.
• W4200309967 cites W2018243782 @default.
• W4200309967 cites W2027091725 @default.
• W4200309967 cites W2047680032 @default.
• W4200309967 cites W2088060652 @default.
• W4200309967 cites W2092158665 @default.
• W4200309967 cites W2093593211 @default.
• W4200309967 cites W2100232797 @default.
• W4200309967 cites W2107774273 @default.
• W4200309967 cites W2114309033 @default.
• W4200309967 cites W2121518329 @default.
• W4200309967 cites W2129572079 @default.
• W4200309967 cites W2129909048 @default.
• W4200309967 cites W2171877884 @default.
• W4200309967 cites W2621858797 @default.
• W4200309967 cites W2809949754 @default.
• W4200309967 cites W2954206106 @default.
• W4200309967 cites W2995794033 @default.
• W4200309967 cites W3128971382 @default.
• W4200309967 cites W4210307510 @default.
• W4200309967 cites W4238714725 @default.
• W4200309967 doi "https://doi.org/10.1210/jendso/bvab169" @default.
• W4200309967 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34988348" @default.
• W4200309967 hasPublicationYear "2021" @default.
• W4200309967 type Work @default.
• W4200309967 citedByCount "4" @default.
• W4200309967 countsByYear W42003099672022 @default.
• W4200309967 countsByYear W42003099672023 @default.
• W4200309967 crossrefType "journal-article" @default.
• W4200309967 hasAuthorship W4200309967A5001416815 @default.
• W4200309967 hasAuthorship W4200309967A5025934150 @default.
• W4200309967 hasAuthorship W4200309967A5034012396 @default.
• W4200309967 hasAuthorship W4200309967A5058425019 @default.
• W4200309967 hasAuthorship W4200309967A5058935003 @default.
• W4200309967 hasAuthorship W4200309967A5072823303 @default.
• W4200309967 hasAuthorship W4200309967A5079316241 @default.
• W4200309967 hasAuthorship W4200309967A5088450261 @default.
• W4200309967 hasBestOaLocation W42003099671 @default.
• W4200309967 hasConcept C119060515 @default.
• W4200309967 hasConcept C126322002 @default.
• W4200309967 hasConcept C134018914 @default.
• W4200309967 hasConcept C151730666 @default.
• W4200309967 hasConcept C156957248 @default.
• W4200309967 hasConcept C167135981 @default.
• W4200309967 hasConcept C2777180221 @default.
• W4200309967 hasConcept C2777538456 @default.
• W4200309967 hasConcept C2779306644 @default.
• W4200309967 hasConcept C2779343474 @default.
• W4200309967 hasConcept C2779435821 @default.
• W4200309967 hasConcept C2779668308 @default.
• W4200309967 hasConcept C555293320 @default.
• W4200309967 hasConcept C71924100 @default.
• W4200309967 hasConcept C86803240 @default.
• W4200309967 hasConcept C90924648 @default.
• W4200309967 hasConceptScore W4200309967C119060515 @default.
• W4200309967 hasConceptScore W4200309967C126322002 @default.
• W4200309967 hasConceptScore W4200309967C134018914 @default.
• W4200309967 hasConceptScore W4200309967C151730666 @default.
• W4200309967 hasConceptScore W4200309967C156957248 @default.
• W4200309967 hasConceptScore W4200309967C167135981 @default.
• W4200309967 hasConceptScore W4200309967C2777180221 @default.
• W4200309967 hasConceptScore W4200309967C2777538456 @default.
• W4200309967 hasConceptScore W4200309967C2779306644 @default.
• W4200309967 hasConceptScore W4200309967C2779343474 @default.
• W4200309967 hasConceptScore W4200309967C2779435821 @default.
• W4200309967 hasConceptScore W4200309967C2779668308 @default.
• W4200309967 hasConceptScore W4200309967C555293320 @default.
• W4200309967 hasConceptScore W4200309967C71924100 @default.
• W4200309967 hasConceptScore W4200309967C86803240 @default.
• W4200309967 hasConceptScore W4200309967C90924648 @default.
• W4200309967 hasFunder F4320332161 @default.
• W4200309967 hasFunder F4320337357 @default.
• W4200309967 hasIssue "1" @default.
• W4200309967 hasLocation W42003099671 @default.
• W4200309967 hasLocation W42003099672 @default.
• W4200309967 hasLocation W42003099673 @default.
• W4200309967 hasOpenAccess W4200309967 @default.
• W4200309967 hasPrimaryLocation W42003099671 @default.
• W4200309967 hasRelatedWork W1581380882 @default.
• W4200309967 hasRelatedWork W2013175287 @default.
• W4200309967 hasRelatedWork W2116128857 @default.
• W4200309967 hasRelatedWork W2285022769 @default.
• W4200309967 hasRelatedWork W2414156024 @default.
• W4200309967 hasRelatedWork W2791774353 @default.

• next