FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200311178> ?p ?o ?g. }

• W4200311178 endingPage "111697" @default.
• W4200311178 startingPage "111697" @default.
• W4200311178 abstract "In this study, four hybrid organic-inorganic compounds (8-H2Q)2[PdCl4] (1), (H2ClQ)2[PdCl4] (2), (H2NQ)2[PdCl4] (3) and (H2MeQ)2[PdCl4]·2H2O (4) (where 8-H2Q = 8-hydroxyquinolinium, H2ClQ = 5-chloro-8-hydroxyquinolinium, H2NQ = 5-nitro-8-hydroxyquinolinium and H2MeQ = 2-methyl-8-hydroxyquinolinium) were synthesized through organic cation modulation. Single-crystal X-ray structure analysis of compounds 1 and 3 indicates that their structures are planar and consist of [PdCl4]2- anions and 8-H2Q or H2NQ cations, respectively. Both ionic components are held together through ionic interactions and hydrogen bonds forming infinite chains linked through π-π interactions to form 2D structures. Furthermore, NMR spectroscopy, UV-Vis spectroscopy, elemental analysis, and FT-IR spectroscopy were used to explore the synthesized compounds. The DNA interaction, antimicrobial activity, antiproliferative activity, and radical scavenging effect of the compounds were evaluated. The hybrid compounds and their free ligands can interact with the calf thymus DNA via an intercalation mode involving the insertion of the aromatic chromophore between the base pairs of DNA; compound 1 has the highest binding affinity. Moreover, they have high antimicrobial efficacy against the tested 14 strains of microorganisms with minimum inhibitory concentration values ranging from <1.95 to 250 μg/mL. The antiproliferative activity of the compounds was investigated against three different cancer cell lines, and their selectivity was verified on mesenchymal stem cells. Compounds 1 and 2 displayed selective and high cytotoxicity against human lung and breast cancer cells and showed moderate cytotoxicity against colon cancer cells. Accordingly, they might be auspicious candidates for future pharmacological investigations in lung and breast cancer research." @default.
• W4200311178 created "2021-12-31" @default.
• W4200311178 creator A5006671972 @default.
• W4200311178 creator A5010590002 @default.
• W4200311178 creator A5024591404 @default.
• W4200311178 creator A5024686169 @default.
• W4200311178 creator A5029681438 @default.
• W4200311178 creator A5036972259 @default.
• W4200311178 creator A5065497369 @default.
• W4200311178 creator A5068427405 @default.
• W4200311178 creator A5068552279 @default.
• W4200311178 creator A5070286149 @default.
• W4200311178 creator A5074839041 @default.
• W4200311178 creator A5077525188 @default.
• W4200311178 date "2022-03-01" @default.
• W4200311178 modified "2023-10-14" @default.
• W4200311178 title "Low-dimensional compounds containing bioactive ligands. Part XVII: Synthesis, structural, spectral and biological properties of hybrid organic-inorganic complexes based on [PdCl4]2− with derivatives of 8-hydroxyquinolinium" @default.
• W4200311178 cites W1232482272 @default.
• W4200311178 cites W1913800443 @default.
• W4200311178 cites W1969360633 @default.
• W4200311178 cites W1984811316 @default.
• W4200311178 cites W1990170643 @default.
• W4200311178 cites W1995456617 @default.
• W4200311178 cites W2006771386 @default.
• W4200311178 cites W2029993320 @default.
• W4200311178 cites W2035441315 @default.
• W4200311178 cites W2042155783 @default.
• W4200311178 cites W2047190819 @default.
• W4200311178 cites W2047212438 @default.
• W4200311178 cites W2053807549 @default.
• W4200311178 cites W2054262069 @default.
• W4200311178 cites W2062062385 @default.
• W4200311178 cites W2063039714 @default.
• W4200311178 cites W2069492141 @default.
• W4200311178 cites W2072734066 @default.
• W4200311178 cites W2075877427 @default.
• W4200311178 cites W2079187416 @default.
• W4200311178 cites W2082645643 @default.
• W4200311178 cites W2089728277 @default.
• W4200311178 cites W2134890652 @default.
• W4200311178 cites W2142812223 @default.
• W4200311178 cites W2145538332 @default.
• W4200311178 cites W2147173298 @default.
• W4200311178 cites W2151708434 @default.
• W4200311178 cites W2165528549 @default.
• W4200311178 cites W2226942738 @default.
• W4200311178 cites W2296423693 @default.
• W4200311178 cites W2296476982 @default.
• W4200311178 cites W2312602247 @default.
• W4200311178 cites W2469094124 @default.
• W4200311178 cites W2575501946 @default.
• W4200311178 cites W2580018907 @default.
• W4200311178 cites W2588912869 @default.
• W4200311178 cites W2738117048 @default.
• W4200311178 cites W2763028915 @default.
• W4200311178 cites W2799303226 @default.
• W4200311178 cites W2800727163 @default.
• W4200311178 cites W2806342682 @default.
• W4200311178 cites W2809417390 @default.
• W4200311178 cites W2889906548 @default.
• W4200311178 cites W2925284280 @default.
• W4200311178 cites W2927192995 @default.
• W4200311178 cites W2948728163 @default.
• W4200311178 cites W2951412678 @default.
• W4200311178 cites W2966173911 @default.
• W4200311178 cites W2972642158 @default.
• W4200311178 cites W2980951935 @default.
• W4200311178 cites W3014250071 @default.
• W4200311178 cites W3014302026 @default.
• W4200311178 cites W3014853594 @default.
• W4200311178 cites W3016953371 @default.
• W4200311178 cites W3034589130 @default.
• W4200311178 cites W3085827013 @default.
• W4200311178 cites W3115897573 @default.
• W4200311178 doi "https://doi.org/10.1016/j.jinorgbio.2021.111697" @default.
• W4200311178 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34999425" @default.
• W4200311178 hasPublicationYear "2022" @default.
• W4200311178 type Work @default.
• W4200311178 citedByCount "3" @default.
• W4200311178 countsByYear W42003111782022 @default.
• W4200311178 countsByYear W42003111782023 @default.
• W4200311178 crossrefType "journal-article" @default.
• W4200311178 hasAuthorship W4200311178A5006671972 @default.
• W4200311178 hasAuthorship W4200311178A5010590002 @default.
• W4200311178 hasAuthorship W4200311178A5024591404 @default.
• W4200311178 hasAuthorship W4200311178A5024686169 @default.
• W4200311178 hasAuthorship W4200311178A5029681438 @default.
• W4200311178 hasAuthorship W4200311178A5036972259 @default.
• W4200311178 hasAuthorship W4200311178A5065497369 @default.
• W4200311178 hasAuthorship W4200311178A5068427405 @default.
• W4200311178 hasAuthorship W4200311178A5068552279 @default.
• W4200311178 hasAuthorship W4200311178A5070286149 @default.
• W4200311178 hasAuthorship W4200311178A5074839041 @default.
• W4200311178 hasAuthorship W4200311178A5077525188 @default.
• W4200311178 hasConcept C103319777 @default.
• W4200311178 hasConcept C109316439 @default.
• W4200311178 hasConcept C118792377 @default.
• W4200311178 hasConcept C137824038 @default.

• next