FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200315419> ?p ?o ?g. }

• W4200315419 abstract "Abstract Aims Although patients with ST segment elevation myocardial infarction (STEMI) and non-ST segment elevation myocardial infarction (NSTEMI) share similar risk factors and similar pathophysiology, their outcomes differ considerably. The Fourth Universal Definition of Myocardial Infarction (UDMI) defined acute myocardial infarction (AMI) by an acute myocardial injury together with clinical evidence of acute myocardial ischaemia. However, the prognostic role of each single diagnostic criteria has never been explored. To evaluate the prognostic role of the different diagnostic criteria of AMI according to the Fourth UDMI in patients with STEMI vs. NSTEMI. Methods and results We enrolled all consecutive patients with AMI undergoing coronary angiogram at our Centre. We used a combination of criteria, according to the current ESC guidelines, to meet the diagnosis, namely the detection of an increase and/or decrease of high-sensitivity cardiac troponin I, with at least one value above the 99th percentile of the upper reference limit and at least one of the following: symptoms of ischaemia; ECG changes (new ST-T changes or new left bundle branch block); development of pathological Q waves in the ECG; echocardiographic evidence of new loss of viable myocardium, or new regional wall motion abnormality. According to the ECG presentation at admission, patients with AMI were divided into STEMI and NSTEMI subgroups. All-cause mortality and a composite endpoint of all-cause mortality, re-hospitalization for heart failure, and myocardial re-infarction were collected. The predictive value of diagnostic criteria alone and their association was evaluated using Kaplan–Meier survival curves and subsequent Cox-regression analysis to find independent predictors of adverse events. 2345 patients were evaluated (41.6% STEMI and 58.4% NSTEMI). The two groups had similar baseline characteristics. The total number of events was 689 (292 in STEMI group and 397 in NSTEMI group). We found that clinical criteria alone showed a positive predictive value in NSTEMI (P &lt; 0.001). Moreover, electrocardiographic and echocardiographic criteria correlated with a worse prognosis in STEMI group (P &lt; 0.01). No other significant prognostic correlation was found. Multivariable Cox-regression model demonstrated that clinical criteria were the only independent predictors of better prognosis in patients with NSTEMI (HR = 0.48; 95% CI: 0.31–0.74; P &lt; 0.001). We did not find any predictor of outcome in patients with STEMI (HR = 0.6; 95% CI: 0.3–1.5, P = 0.3; HR = 1.1; 95% CI: 0.5–2.6, P = 0.7; HR = 0.6; 95% CI: 0.3–1.2, P = 0.2 for clinical and echocardiographic criteria alone and their combination, respectively). Conclusions Our data suggest that in NSTEMI the prognosis is considerably better if clinical criteria alone are present at admission. We hypothesize that the absence of electrocardiographic and echocardiographic alterations in NSTEMI could indirectly indicate smaller infarct sizes or other causes of acute myocardial injury." @default.
• W4200315419 created "2021-12-31" @default.
• W4200315419 creator A5010241678 @default.
• W4200315419 creator A5030742489 @default.
• W4200315419 creator A5033930135 @default.
• W4200315419 creator A5039188583 @default.
• W4200315419 creator A5041787832 @default.
• W4200315419 creator A5047544416 @default.
• W4200315419 creator A5049432842 @default.
• W4200315419 creator A5053033724 @default.
• W4200315419 creator A5063677699 @default.
• W4200315419 creator A5065469571 @default.
• W4200315419 creator A5067676269 @default.
• W4200315419 creator A5078420807 @default.
• W4200315419 creator A5079761805 @default.
• W4200315419 creator A5080923345 @default.
• W4200315419 creator A5084550471 @default.
• W4200315419 date "2021-12-01" @default.
• W4200315419 modified "2023-10-14" @default.
• W4200315419 title "251 Prognostic role of acute myocardial infarction diagnostic criteria in non-ST segment elevation myocardial infarction" @default.
• W4200315419 doi "https://doi.org/10.1093/eurheartj/suab140.043" @default.
• W4200315419 hasPublicationYear "2021" @default.
• W4200315419 type Work @default.
• W4200315419 citedByCount "0" @default.
• W4200315419 crossrefType "journal-article" @default.
• W4200315419 hasAuthorship W4200315419A5010241678 @default.
• W4200315419 hasAuthorship W4200315419A5030742489 @default.
• W4200315419 hasAuthorship W4200315419A5033930135 @default.
• W4200315419 hasAuthorship W4200315419A5039188583 @default.
• W4200315419 hasAuthorship W4200315419A5041787832 @default.
• W4200315419 hasAuthorship W4200315419A5047544416 @default.
• W4200315419 hasAuthorship W4200315419A5049432842 @default.
• W4200315419 hasAuthorship W4200315419A5053033724 @default.
• W4200315419 hasAuthorship W4200315419A5063677699 @default.
• W4200315419 hasAuthorship W4200315419A5065469571 @default.
• W4200315419 hasAuthorship W4200315419A5067676269 @default.
• W4200315419 hasAuthorship W4200315419A5078420807 @default.
• W4200315419 hasAuthorship W4200315419A5079761805 @default.
• W4200315419 hasAuthorship W4200315419A5080923345 @default.
• W4200315419 hasAuthorship W4200315419A5084550471 @default.
• W4200315419 hasBestOaLocation W42003154191 @default.
• W4200315419 hasConcept C126322002 @default.
• W4200315419 hasConcept C164705383 @default.
• W4200315419 hasConcept C2771771 @default.
• W4200315419 hasConcept C2777473070 @default.
• W4200315419 hasConcept C2777798775 @default.
• W4200315419 hasConcept C2778050738 @default.
• W4200315419 hasConcept C2778198053 @default.
• W4200315419 hasConcept C2780040984 @default.
• W4200315419 hasConcept C36036425 @default.
• W4200315419 hasConcept C500558357 @default.
• W4200315419 hasConcept C71924100 @default.
• W4200315419 hasConceptScore W4200315419C126322002 @default.
• W4200315419 hasConceptScore W4200315419C164705383 @default.
• W4200315419 hasConceptScore W4200315419C2771771 @default.
• W4200315419 hasConceptScore W4200315419C2777473070 @default.
• W4200315419 hasConceptScore W4200315419C2777798775 @default.
• W4200315419 hasConceptScore W4200315419C2778050738 @default.
• W4200315419 hasConceptScore W4200315419C2778198053 @default.
• W4200315419 hasConceptScore W4200315419C2780040984 @default.
• W4200315419 hasConceptScore W4200315419C36036425 @default.
• W4200315419 hasConceptScore W4200315419C500558357 @default.
• W4200315419 hasConceptScore W4200315419C71924100 @default.
• W4200315419 hasIssue "Supplement_G" @default.
• W4200315419 hasLocation W42003154191 @default.
• W4200315419 hasOpenAccess W4200315419 @default.
• W4200315419 hasPrimaryLocation W42003154191 @default.
• W4200315419 hasRelatedWork W197768352 @default.
• W4200315419 hasRelatedWork W1977792494 @default.
• W4200315419 hasRelatedWork W2028226140 @default.
• W4200315419 hasRelatedWork W2035030275 @default.
• W4200315419 hasRelatedWork W2050742307 @default.
• W4200315419 hasRelatedWork W2062502632 @default.
• W4200315419 hasRelatedWork W2093502227 @default.
• W4200315419 hasRelatedWork W2141353574 @default.
• W4200315419 hasRelatedWork W2155095884 @default.
• W4200315419 hasRelatedWork W4205975584 @default.
• W4200315419 hasVolume "23" @default.
• W4200315419 isParatext "false" @default.
• W4200315419 isRetracted "false" @default.
• W4200315419 workType "article" @default.