FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200319076> ?p ?o ?g. }

• W4200319076 abstract "Background Accurate estimation of survival and recurrence are important to inform decisions regarding therapy and surveillance. We sought to design and validate a dynamic prognostic model for patients undergoing resection for gastric adenocarcinoma. Methods Patients who underwent curative-intent surgery for gastric adenocarcinoma between 2000 and 2020 were identified using a multi-institutional database. Landmark analysis was used to create dynamic OS and DFS prediction models. Model performance was internally cross-validated via bootstrap resampling. Results Among 895 patients, 507 (57.2%) patients underwent partial gastrectomy (n = 507, 57.2%) while 380 (42.8%) had total gastrectomy. Median tumor size was 40 mm (IQR: 25–65), most tumors were located in the antrum (n = 344, 39.5%) and infiltrated the subserosa (T3 tumors: n = 283, 31.9%) or serosa (T4 tumors: n = 253, 28.5%); lymph node metastasis occurred in 528 (59.1%) patients. Median OS and DFS were 17.5 (IQR: 7.5–42.8) and 14.3 months (IQR: 6.5–39.9), respectively. The impact of age, sex, preoperative comorbidities, tumor size and location, extent of lymphadenectomy and total number of lymph nodes examined, Lauren class, T and N category, postoperative complications, and tumor recurrence varied over time (all p < 0.05). An online tool to predict dynamic OS and DFS based on patient survival relative to time survived was developed and made available for clinical use. Discrimination ability of OS and DFS was excellent (C-index: 0.84 and 0.86, respectively) and calibration plots revealed good prediction. Conclusions An online dynamic prognostic tool was developed and validated to predict OS and DFS following resection of gastric adenocarcinoma. Landmark analysis to predict long-term outcomes based on follow-up time may be helpful to surgeons and patients." @default.
• W4200319076 created "2021-12-31" @default.
• W4200319076 creator A5012796096 @default.
• W4200319076 creator A5016519845 @default.
• W4200319076 creator A5027872333 @default.
• W4200319076 creator A5052875930 @default.
• W4200319076 creator A5053538488 @default.
• W4200319076 creator A5059255330 @default.
• W4200319076 creator A5060542608 @default.
• W4200319076 creator A5065551581 @default.
• W4200319076 creator A5080464842 @default.
• W4200319076 creator A5081302342 @default.
• W4200319076 creator A5089834205 @default.
• W4200319076 creator A5091162926 @default.
• W4200319076 date "2021-12-01" @default.
• W4200319076 modified "2023-09-27" @default.
• W4200319076 title "Dynamic Prediction of Survival after Curative Resection of Gastric Adenocarcinoma: A landmarking-based analysis" @default.
• W4200319076 cites W1564885986 @default.
• W4200319076 cites W1859449693 @default.
• W4200319076 cites W1967835489 @default.
• W4200319076 cites W1979700661 @default.
• W4200319076 cites W1985213644 @default.
• W4200319076 cites W1989098330 @default.
• W4200319076 cites W2002748327 @default.
• W4200319076 cites W2003474640 @default.
• W4200319076 cites W2033381976 @default.
• W4200319076 cites W2039254513 @default.
• W4200319076 cites W2039887347 @default.
• W4200319076 cites W2046379339 @default.
• W4200319076 cites W2049036294 @default.
• W4200319076 cites W2051063891 @default.
• W4200319076 cites W2055827929 @default.
• W4200319076 cites W2076221207 @default.
• W4200319076 cites W2096998881 @default.
• W4200319076 cites W2108818539 @default.
• W4200319076 cites W2113947048 @default.
• W4200319076 cites W2133593152 @default.
• W4200319076 cites W2134187169 @default.
• W4200319076 cites W2137202681 @default.
• W4200319076 cites W2145997692 @default.
• W4200319076 cites W2146084269 @default.
• W4200319076 cites W2151396892 @default.
• W4200319076 cites W2152407292 @default.
• W4200319076 cites W2170490301 @default.
• W4200319076 cites W2294169416 @default.
• W4200319076 cites W2536596501 @default.
• W4200319076 cites W2581500274 @default.
• W4200319076 cites W2603335347 @default.
• W4200319076 cites W2754408511 @default.
• W4200319076 cites W2774752450 @default.
• W4200319076 cites W2800257421 @default.
• W4200319076 cites W2889646458 @default.
• W4200319076 cites W2938258277 @default.
• W4200319076 cites W2991337672 @default.
• W4200319076 cites W3006066818 @default.
• W4200319076 cites W3009117051 @default.
• W4200319076 cites W3031948177 @default.
• W4200319076 cites W3038001761 @default.
• W4200319076 cites W3041101734 @default.
• W4200319076 cites W3044697869 @default.
• W4200319076 cites W4210990885 @default.
• W4200319076 cites W4297832830 @default.
• W4200319076 cites W822878543 @default.
• W4200319076 doi "https://doi.org/10.1016/j.ejso.2021.11.127" @default.
• W4200319076 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34895773" @default.
• W4200319076 hasPublicationYear "2021" @default.
• W4200319076 type Work @default.
• W4200319076 citedByCount "0" @default.
• W4200319076 crossrefType "journal-article" @default.
• W4200319076 hasAuthorship W4200319076A5012796096 @default.
• W4200319076 hasAuthorship W4200319076A5016519845 @default.
• W4200319076 hasAuthorship W4200319076A5027872333 @default.
• W4200319076 hasAuthorship W4200319076A5052875930 @default.
• W4200319076 hasAuthorship W4200319076A5053538488 @default.
• W4200319076 hasAuthorship W4200319076A5059255330 @default.
• W4200319076 hasAuthorship W4200319076A5060542608 @default.
• W4200319076 hasAuthorship W4200319076A5065551581 @default.
• W4200319076 hasAuthorship W4200319076A5080464842 @default.
• W4200319076 hasAuthorship W4200319076A5081302342 @default.
• W4200319076 hasAuthorship W4200319076A5089834205 @default.
• W4200319076 hasAuthorship W4200319076A5091162926 @default.
• W4200319076 hasConcept C121608353 @default.
• W4200319076 hasConcept C126322002 @default.
• W4200319076 hasConcept C141071460 @default.
• W4200319076 hasConcept C143998085 @default.
• W4200319076 hasConcept C2780470880 @default.
• W4200319076 hasConcept C2780824555 @default.
• W4200319076 hasConcept C2780849966 @default.
• W4200319076 hasConcept C2781182431 @default.
• W4200319076 hasConcept C2993283237 @default.
• W4200319076 hasConcept C71924100 @default.
• W4200319076 hasConcept C90924648 @default.
• W4200319076 hasConceptScore W4200319076C121608353 @default.
• W4200319076 hasConceptScore W4200319076C126322002 @default.
• W4200319076 hasConceptScore W4200319076C141071460 @default.
• W4200319076 hasConceptScore W4200319076C143998085 @default.
• W4200319076 hasConceptScore W4200319076C2780470880 @default.
• W4200319076 hasConceptScore W4200319076C2780824555 @default.
• W4200319076 hasConceptScore W4200319076C2780849966 @default.
• W4200319076 hasConceptScore W4200319076C2781182431 @default.

• next