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- W4200320070 abstract "Functional genomic screening of genetic mutant libraries enables the characterization of gene function in diverse organisms. For the fungal pathogen Candida albicans, several genetic mutant libraries have been generated and screened for diverse phenotypes, including tolerance to environmental stressors and antifungal drugs, and pathogenic traits such as cellular morphogenesis, biofilm formation and host-pathogen interactions. Here, we compile and organize C. albicans functional genomic screening data from ∼400 screens, to generate a data library of genetic mutant strains analyzed under diverse conditions. For quantitative screening data, we normalized these results to enable quantitative and comparative analysis of different genes across different phenotypes. Together, this provides a unique C. albicans genetic database, summarizing abundant phenotypic data from functional genomic screens in this critical fungal pathogen." @default.
- W4200320070 created "2021-12-31" @default.
- W4200320070 creator A5015142982 @default.
- W4200320070 creator A5046465030 @default.
- W4200320070 creator A5085487243 @default.
- W4200320070 date "2021-11-01" @default.
- W4200320070 modified "2023-10-11" @default.
- W4200320070 title "A data library of <i>Candida albicans</i> functional genomic screens" @default.
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- W4200320070 doi "https://doi.org/10.1093/femsyr/foab060" @default.
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