Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200322457> ?p ?o ?g. }
Showing items 1 to 98 of
98
with 100 items per page.
- W4200322457 endingPage "49" @default.
- W4200322457 startingPage "49" @default.
- W4200322457 abstract "(1) Background: Biomarkers of efficacy for subcutaneous immunotherapy (SCIT) on allergic rhinitis have not been evaluated in details. The present study aims to assess the relevance of measuring of sIgE, sIgG4 and IgE/IgG4 ratio during SCIT in patients with allergic rhinitis; (2) Methods: 20 patients, 13 men and 7 women aged 19 to 58 years, with clinically manifested seasonal and perennial allergic rhinitis were studied. At the initiation and in the end of the three-year course of SCIT serum allergen-specific IgE and IgG4 were measured with ImmunoCAP system. The sIgE/sIgG4 ratio was calculated as a biomarker for immunologic effectiveness; (3) Results: There was a significant increase of sIgG4 antibodies (p < 0.05), while at the end of SCIT for the sIgE levels no significant changes were seen (p > 0.05). Moreover, 90% of patients showed a decrease of the IgE/IgG4 ratio; (4) Conclusions: In most of treated patients with AR, SCIT with Bulgarian allergen products leads to clear immunological changes. After a 3-year of SCIT there is a significant increase in allergen specific IgG4 levels and both decrease of sIgE and IgE/IgG4 ratio. sIgE, sIgG4 and IgE/IgG4 ratio can be used as a substantial biomarker for predicting immunological effectiveness of SCIT." @default.
- W4200322457 created "2021-12-31" @default.
- W4200322457 creator A5007163430 @default.
- W4200322457 creator A5016853784 @default.
- W4200322457 creator A5029800909 @default.
- W4200322457 creator A5038276045 @default.
- W4200322457 creator A5064595355 @default.
- W4200322457 creator A5078527021 @default.
- W4200322457 date "2021-12-07" @default.
- W4200322457 modified "2023-10-16" @default.
- W4200322457 title "Allergen-Specific IgE and IgG4 as Biomarkers for Immunologic Changes during Subcutaneous Allergen Immunotherapy" @default.
- W4200322457 cites W1490916211 @default.
- W4200322457 cites W1502002865 @default.
- W4200322457 cites W1577022278 @default.
- W4200322457 cites W1694898543 @default.
- W4200322457 cites W1789167748 @default.
- W4200322457 cites W1852192552 @default.
- W4200322457 cites W1973688027 @default.
- W4200322457 cites W2000815418 @default.
- W4200322457 cites W2014513314 @default.
- W4200322457 cites W2022618190 @default.
- W4200322457 cites W2050656150 @default.
- W4200322457 cites W2055184133 @default.
- W4200322457 cites W2086505793 @default.
- W4200322457 cites W2107074680 @default.
- W4200322457 cites W2132844265 @default.
- W4200322457 cites W2148903359 @default.
- W4200322457 cites W2585773786 @default.
- W4200322457 cites W2611671906 @default.
- W4200322457 cites W2612676663 @default.
- W4200322457 cites W2810415058 @default.
- W4200322457 doi "https://doi.org/10.3390/antib10040049" @default.
- W4200322457 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/34940001" @default.
- W4200322457 hasPublicationYear "2021" @default.
- W4200322457 type Work @default.
- W4200322457 citedByCount "5" @default.
- W4200322457 countsByYear W42003224572022 @default.
- W4200322457 countsByYear W42003224572023 @default.
- W4200322457 crossrefType "journal-article" @default.
- W4200322457 hasAuthorship W4200322457A5007163430 @default.
- W4200322457 hasAuthorship W4200322457A5016853784 @default.
- W4200322457 hasAuthorship W4200322457A5029800909 @default.
- W4200322457 hasAuthorship W4200322457A5038276045 @default.
- W4200322457 hasAuthorship W4200322457A5064595355 @default.
- W4200322457 hasAuthorship W4200322457A5078527021 @default.
- W4200322457 hasBestOaLocation W42003224571 @default.
- W4200322457 hasConcept C126322002 @default.
- W4200322457 hasConcept C141105273 @default.
- W4200322457 hasConcept C159654299 @default.
- W4200322457 hasConcept C170493617 @default.
- W4200322457 hasConcept C203014093 @default.
- W4200322457 hasConcept C207480886 @default.
- W4200322457 hasConcept C2777701055 @default.
- W4200322457 hasConcept C2779779143 @default.
- W4200322457 hasConcept C2780510475 @default.
- W4200322457 hasConcept C2781197716 @default.
- W4200322457 hasConcept C55493867 @default.
- W4200322457 hasConcept C71924100 @default.
- W4200322457 hasConcept C86803240 @default.
- W4200322457 hasConcept C8891405 @default.
- W4200322457 hasConceptScore W4200322457C126322002 @default.
- W4200322457 hasConceptScore W4200322457C141105273 @default.
- W4200322457 hasConceptScore W4200322457C159654299 @default.
- W4200322457 hasConceptScore W4200322457C170493617 @default.
- W4200322457 hasConceptScore W4200322457C203014093 @default.
- W4200322457 hasConceptScore W4200322457C207480886 @default.
- W4200322457 hasConceptScore W4200322457C2777701055 @default.
- W4200322457 hasConceptScore W4200322457C2779779143 @default.
- W4200322457 hasConceptScore W4200322457C2780510475 @default.
- W4200322457 hasConceptScore W4200322457C2781197716 @default.
- W4200322457 hasConceptScore W4200322457C55493867 @default.
- W4200322457 hasConceptScore W4200322457C71924100 @default.
- W4200322457 hasConceptScore W4200322457C86803240 @default.
- W4200322457 hasConceptScore W4200322457C8891405 @default.
- W4200322457 hasFunder F4320321843 @default.
- W4200322457 hasIssue "4" @default.
- W4200322457 hasLocation W42003224571 @default.
- W4200322457 hasLocation W42003224572 @default.
- W4200322457 hasLocation W42003224573 @default.
- W4200322457 hasLocation W42003224574 @default.
- W4200322457 hasOpenAccess W4200322457 @default.
- W4200322457 hasPrimaryLocation W42003224571 @default.
- W4200322457 hasRelatedWork W1561459166 @default.
- W4200322457 hasRelatedWork W1978441684 @default.
- W4200322457 hasRelatedWork W2006108005 @default.
- W4200322457 hasRelatedWork W2032428509 @default.
- W4200322457 hasRelatedWork W2065141443 @default.
- W4200322457 hasRelatedWork W2125584695 @default.
- W4200322457 hasRelatedWork W2383002280 @default.
- W4200322457 hasRelatedWork W2411933361 @default.
- W4200322457 hasRelatedWork W4245063876 @default.
- W4200322457 hasRelatedWork W4385706107 @default.
- W4200322457 hasVolume "10" @default.
- W4200322457 isParatext "false" @default.
- W4200322457 isRetracted "false" @default.
- W4200322457 workType "article" @default.