Matches in SemOpenAlex for { <https://semopenalex.org/work/W4200326539> ?p ?o ?g. }
- W4200326539 endingPage "7090" @default.
- W4200326539 startingPage "7079" @default.
- W4200326539 abstract "Lung cancer is characterized by high morbidity and mortality rates, and its occurrence is associated with many types of cell death. As a new form of regulated cell death, ferroptosis is an iron- dependent pattern of cell death and characterized by lethal accumulation of lipid-based reactive oxygen species (ROS), which is different from apoptosis, necrosis and autophagy at both the morphological and biochemical levels. It plays an important role in the development of lung cancer and induction of ferroptosis in lung cancer cells has become a new strategy for anti- lung cancer treatment. However, a few reviews summarized ferroptosis and its role in lung cancer has not been elucidated, and the precise mechanism of ferroptosis modeling lung cancer has not yet been revealed till date. Herein, we review the latest literature on the process of ferroptosis regarding lung cancer, including basic molecular or biology mechanistic studies both in vivo and in vitro, as well as human studies with a more translational or clinical approach. This review provides a practical, concise and updated outline on the mechanisms and therapeutic strategies in lung cancer with ferroptosis alterations. Looking ahead, further studies are required to uncover the possible modulatory relationship between ferroptosis and lung cancer." @default.
- W4200326539 created "2021-12-31" @default.
- W4200326539 creator A5000647412 @default.
- W4200326539 creator A5024887366 @default.
- W4200326539 creator A5025935512 @default.
- W4200326539 creator A5030683638 @default.
- W4200326539 date "2021-12-01" @default.
- W4200326539 modified "2023-10-07" @default.
- W4200326539 title "Ferroptosis and Its Potential Role in Lung Cancer: Updated Evidence from Pathogenesis to Therapy" @default.
- W4200326539 cites W1968642527 @default.
- W4200326539 cites W1972363323 @default.
- W4200326539 cites W1994476571 @default.
- W4200326539 cites W1997183854 @default.
- W4200326539 cites W2004684605 @default.
- W4200326539 cites W2010255330 @default.
- W4200326539 cites W2022571865 @default.
- W4200326539 cites W2034103505 @default.
- W4200326539 cites W2039688795 @default.
- W4200326539 cites W2066226784 @default.
- W4200326539 cites W2072862521 @default.
- W4200326539 cites W2085008931 @default.
- W4200326539 cites W2124103287 @default.
- W4200326539 cites W2132495634 @default.
- W4200326539 cites W2134529736 @default.
- W4200326539 cites W2135114425 @default.
- W4200326539 cites W2143034911 @default.
- W4200326539 cites W2147896673 @default.
- W4200326539 cites W2162420845 @default.
- W4200326539 cites W2189205651 @default.
- W4200326539 cites W2302101601 @default.
- W4200326539 cites W2327686392 @default.
- W4200326539 cites W2336303575 @default.
- W4200326539 cites W2508296626 @default.
- W4200326539 cites W2550324626 @default.
- W4200326539 cites W2619512829 @default.
- W4200326539 cites W2762656910 @default.
- W4200326539 cites W2786707817 @default.
- W4200326539 cites W2803347838 @default.
- W4200326539 cites W2803414994 @default.
- W4200326539 cites W2807141660 @default.
- W4200326539 cites W2884973466 @default.
- W4200326539 cites W2889646458 @default.
- W4200326539 cites W2896690111 @default.
- W4200326539 cites W2900771119 @default.
- W4200326539 cites W2909955689 @default.
- W4200326539 cites W2943793201 @default.
- W4200326539 cites W2948529153 @default.
- W4200326539 cites W2955179958 @default.
- W4200326539 cites W2967615620 @default.
- W4200326539 cites W2971048027 @default.
- W4200326539 cites W2979398595 @default.
- W4200326539 cites W2981179816 @default.
- W4200326539 cites W2993568883 @default.
- W4200326539 cites W2998103954 @default.
- W4200326539 cites W3000233190 @default.
- W4200326539 cites W3003960907 @default.
- W4200326539 cites W3021534378 @default.
- W4200326539 cites W3026346985 @default.
- W4200326539 cites W3034353096 @default.
- W4200326539 cites W3037778259 @default.
- W4200326539 cites W3044631785 @default.
- W4200326539 cites W3084631824 @default.
- W4200326539 cites W3088238664 @default.
- W4200326539 cites W3092278692 @default.
- W4200326539 cites W3123328978 @default.
- W4200326539 cites W3127839532 @default.
- W4200326539 cites W3129733332 @default.
- W4200326539 cites W3134840300 @default.
- W4200326539 cites W3135176588 @default.
- W4200326539 cites W3135679583 @default.
- W4200326539 cites W3146768338 @default.
- W4200326539 cites W3158198742 @default.
- W4200326539 cites W3159166410 @default.
- W4200326539 cites W3159595877 @default.
- W4200326539 cites W3160988284 @default.
- W4200326539 cites W3162231878 @default.
- W4200326539 cites W3165180186 @default.
- W4200326539 cites W3165375330 @default.
- W4200326539 cites W3169941200 @default.
- W4200326539 cites W3174608737 @default.
- W4200326539 cites W3175275490 @default.
- W4200326539 cites W3175901505 @default.
- W4200326539 cites W3177084210 @default.
- W4200326539 cites W3177943381 @default.
- W4200326539 cites W3178408874 @default.
- W4200326539 cites W3184119447 @default.
- W4200326539 cites W3184348546 @default.
- W4200326539 cites W3186079197 @default.
- W4200326539 cites W3186538660 @default.
- W4200326539 cites W3193866530 @default.
- W4200326539 cites W3195727767 @default.
- W4200326539 cites W3196485559 @default.
- W4200326539 cites W3197245165 @default.
- W4200326539 cites W3197629250 @default.
- W4200326539 cites W3197937462 @default.
- W4200326539 cites W3198102097 @default.
- W4200326539 cites W3198712632 @default.
- W4200326539 cites W3200359300 @default.